RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "Subramanyam, C."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 20 Structures.

Refinements

Structure Determination Methodology

experimental (20)

Scientific Name of Source Organism

	Homo sapiens (14)
	Ovis aries (5)
	Rattus norvegicus (5)
	synthetic construct (2)
	Gallus gallus (1)
	Staphylococcus aureus (1)

Taxonomy

	Eukaryota (19)
	Eukaryota (eukaryotes) (2)
	other sequences (2)
	Bacteria (1)

Experimental Method

X-RAY DIFFRACTION (20)

Polymer Entity Type

Protein (20)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (3)
	2.0 - 2.5 (11)
	2.5 - 3.0 (1)
	3.0 - 3.5 (2)
	3.5 - 4.0 (2)

Release Date

	2005 - 2009 (2)
	2010 - 2014 (3)
	2015 - 2019 (8)
	2020 - 2024 (7)

Enzyme Classification Name

	Transferases (12)
	Oxidoreductases (2)
	Hydrolases (1)

Symmetry Type

	Asymmetric (19)
	Cyclic (1)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (13)
	Alpha and beta proteins (a/b) (4)
	All alpha proteins (3)
	Artifacts (1)

AllSelected

1 to 20 of 20 Structures

Page 1 of 1

Sort by

Explore in 3D

1YOU \| pdb_00001you	Download File View File

Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor

Pandit, J.

(2005) Bioorg Med Chem Lett 15: 1807-1810

Released	2005-03-15
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Collagenase 3 (protein)
Unique Ligands	CA, PFD, SO4, ZN

Explore in 3D

2W9T \| pdb_00002w9t	Download File View File

Staphylococcus aureus S1:DHFR

Soutter, H.H., Miller, J.R.

(2009) Proteins 76: 706

Released	2009-03-24
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Staphylococcus aureus
Macromolecule	DIHYDROFOLATE REDUCTASE TYPE 1 (protein)

Explore in 3D

3MV5 \| pdb_00003mv5	Download File View File

Crystal structure of Akt-1-inhibitor complexes

Pandit, J.

(2010) J Med Chem 53: 4615-4622

Released	2010-06-02
Method	X-RAY DIFFRACTION 2.47 Å
Organisms	Homo sapiens
Macromolecule	GSK3-beta peptide (protein) v-akt murine thymoma viral oncogene homolog 1 (AKT1) (protein)
Unique Ligands	MN, XFE

Explore in 3D

3MVH \| pdb_00003mvh	Download File View File

Crystal structure of Akt-1-inhibitor complexes

Pandit, J.

(2010) J Med Chem 53: 4615-4622

Released	2010-06-02
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	GSK3-beta peptide (protein) v-akt murine thymoma viral oncogene homolog 1 (AKT1) (protein)
Unique Ligands	MN, WFE

Explore in 3D

3MVJ \| pdb_00003mvj	Download File View File

Human cyclic AMP-dependent protein kinase PKA inhibitor complex

Pandit, J., Vajdos, F.

(2010) J Med Chem 53: 4615-4622

Released	2010-06-02
Method	X-RAY DIFFRACTION 2.49 Å
Organisms	Homo sapiens
Macromolecule	cAMP-dependent protein kinase catalytic subunit alpha (protein) cAMP-dependent protein kinase inhibitor alpha (protein)
Unique Ligands	XFE

Explore in 3D

4X1I \| pdb_00004x1i	Download File View File

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

Parris, K.D.

(2014) J Med Chem 57: 10527-10543

Released	2015-03-25
Method	X-RAY DIFFRACTION 3.11 Å
Organisms	Ovis aries Rattus norvegicus
Macromolecule	Stathmin-4 (protein) Tubulin alpha chain (protein) Tubulin beta chain (protein)
Unique Ligands	3WD, GDP, GTP, LOC, MG

Explore in 3D

4X1K \| pdb_00004x1k	Download File View File

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

Parris, K.D.

(2014) J Med Chem 57: 10527-10543

Released	2015-03-25
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Ovis aries Rattus norvegicus
Macromolecule	Stathmin-4 (protein) Tubulin alpha chain (protein) Tubulin beta chain (protein)
Unique Ligands	3WZ, GDP, GTP, LOC, MG

Explore in 3D

4X1Y \| pdb_00004x1y	Download File View File

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

Parris, K.D.

(2014) J Med Chem 57: 10527-10543

Released	2015-03-25
Method	X-RAY DIFFRACTION 3.19 Å
Organisms	Ovis aries Rattus norvegicus
Macromolecule	Stathmin-4 (protein) Tubulin alpha chain (protein) Tubulin beta chain (protein)
Unique Ligands	3WV, GDP, GTP, LOC, MG

Explore in 3D

4X20 \| pdb_00004x20	Download File View File

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

Parris, K.D.

(2014) J Med Chem 57: 10527-10543

Released	2015-03-25
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Ovis aries Rattus norvegicus
Macromolecule	Stathmin-4 (protein) Tubulin alpha chain (protein) Tubulin beta chain (protein)
Unique Ligands	3WY, GDP, GTP, LOC, MG

Explore in 3D

5KX5 \| pdb_00005kx5	Download File View File

Crystal structure of tubulin-stathmin-TTL-Compound 11 complex

Parris, K.

(2016) ACS Med Chem Lett 7: 999-1004

Released	2016-12-28
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Gallus gallus Ovis aries Rattus norvegicus
Macromolecule	Stathmin-4 (protein) TTL protein (protein) Tubulin alpha chain (protein) Tubulin beta chain (protein)
Unique Ligands	6YK, ADP, CA, GDP, GTP, MG

Explore in 3D

5W4W \| pdb_00005w4w	Download File View File

Identification and Profiling of a Selective and Brain Penetrant Radioligand for In Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

Liu, S.

(2017) ACS Chem Neurosci 8: 1995-2004

Released	2017-06-28
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens
Macromolecule	Casein kinase I isoform delta (protein)
Unique Ligands	9WG, SO4

Explore in 3D

5Z1D \| pdb_00005z1d	Download File View File

MAP2K7 C276S mutant-inhibitor

Kinoshita, T., London, N.

(2019) Cell Chem Biol 26: 98-108.e5

Released	2019-01-02
Method	X-RAY DIFFRACTION 2.28 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 7 (protein)
Unique Ligands	95U, EPE

Explore in 3D

5Z1E \| pdb_00005z1e	Download File View File

MAP2K7 C218S mutant-inhibitor

Kinoshita, T., London, N.

(2019) Cell Chem Biol 26: 98-108.e5

Released	2019-01-02
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 7 (protein)
Unique Ligands	95U

Explore in 3D

6WF3 \| pdb_00006wf3	Download File View File

Crystal structure of human Naa50 in complex with a cofactor derived inhibitor (compound 1)

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 2.291 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	ACE-MET-LEU-GLY-PRO-NH2 (protein) N-alpha-acetyltransferase 50 (protein)
Unique Ligands	COA

Explore in 3D

6WF5 \| pdb_00006wf5	Download File View File

Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2)

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 2.04 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	ACE-MET-LEU-GLY-PRO-NH2 (protein) N-alpha-acetyltransferase 50 (protein)
Unique Ligands	U44

Explore in 3D

6WFG \| pdb_00006wfg	Download File View File

Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 2.16 Å
Organisms	Homo sapiens
Macromolecule	N-alpha-acetyltransferase 50 (protein)
Unique Ligands	COA, U3V

Explore in 3D

6WFK \| pdb_00006wfk	Download File View File

Crystal structure of human Naa50 in complex with CoA and an inhibitor (compound 4a) identified using DNA encoded library technology

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Homo sapiens
Macromolecule	N-alpha-acetyltransferase 50 (protein)
Unique Ligands	COA, U2J

Explore in 3D

6WFN \| pdb_00006wfn	Download File View File

Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4a) identified using DNA encoded library technology

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.07 Å
Organisms	Homo sapiens
Macromolecule	N-alpha-acetyltransferase 50 (protein)
Unique Ligands	ACO, U2J

Explore in 3D

6WFO \| pdb_00006wfo	Download File View File

Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4b) identified using DNA encoded library technology

Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E.

(2020) ACS Med Chem Lett 11: 1175-1184

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	N-alpha-acetyltransferase 50 (protein)
Unique Ligands	ACO, U3Y

Explore in 3D

7O4D \| pdb_00007o4d	Download File View File

QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline

Gould, N.L., Scherer, G.R., Carvalh, S., Shurrush, K., Edry, E., Elkobi, A., David, O., Dym, O., Albeck, S., Peleg, Y., Germain, N., Babaev, I., Sharir, H., Lefker, B., Subramanyam, C., Barr, H., Rosenblum, K.

(2023) J Clin Invest 133:

Released	2022-08-17
Method	X-RAY DIFFRACTION 2.249 Å
Organisms	Homo sapiens
Macromolecule	Ribosyldihydronicotinamide dehydrogenase [quinone] (protein)
Unique Ligands	FAD, SO4, V1Z, ZN

1 to 20 of 20 Structures

Page 1 of 1

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1YOU | pdb_00001you

Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor

2W9T | pdb_00002w9t

Staphylococcus aureus S1:DHFR

3MV5 | pdb_00003mv5

Crystal structure of Akt-1-inhibitor complexes

3MVH | pdb_00003mvh

Crystal structure of Akt-1-inhibitor complexes

3MVJ | pdb_00003mvj

Human cyclic AMP-dependent protein kinase PKA inhibitor complex

4X1I | pdb_00004x1i

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

4X1K | pdb_00004x1k

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

4X1Y | pdb_00004x1y

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

4X20 | pdb_00004x20

Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications

5KX5 | pdb_00005kx5

Crystal structure of tubulin-stathmin-TTL-Compound 11 complex

5W4W | pdb_00005w4w

Identification and Profiling of a Selective and Brain Penetrant Radioligand for In Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) Inhibitors

5Z1D | pdb_00005z1d

MAP2K7 C276S mutant-inhibitor

5Z1E | pdb_00005z1e

MAP2K7 C218S mutant-inhibitor

6WF3 | pdb_00006wf3

Crystal structure of human Naa50 in complex with a cofactor derived inhibitor (compound 1)

6WF5 | pdb_00006wf5

Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2)

6WFG | pdb_00006wfg

Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology

6WFK | pdb_00006wfk

Crystal structure of human Naa50 in complex with CoA and an inhibitor (compound 4a) identified using DNA encoded library technology

6WFN | pdb_00006wfn

Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4a) identified using DNA encoded library technology

6WFO | pdb_00006wfo

Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4b) identified using DNA encoded library technology

7O4D | pdb_00007o4d

QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1YOU | pdb_00001you

2W9T | pdb_00002w9t

3MV5 | pdb_00003mv5

3MVH | pdb_00003mvh

3MVJ | pdb_00003mvj

4X1I | pdb_00004x1i

4X1K | pdb_00004x1k

4X1Y | pdb_00004x1y

4X20 | pdb_00004x20

5KX5 | pdb_00005kx5

5W4W | pdb_00005w4w

5Z1D | pdb_00005z1d

5Z1E | pdb_00005z1e

6WF3 | pdb_00006wf3

6WF5 | pdb_00006wf5

6WFG | pdb_00006wfg

6WFK | pdb_00006wfk

6WFN | pdb_00006wfn

6WFO | pdb_00006wfo

7O4D | pdb_00007o4d