8YQW | pdb_00008yqw

ASFV RNA polymerase-M1249L complex3

PDB DOI: https://doi.org/10.2210/pdb8YQW/pdb
EM Map EMD-39508: EMDB EMDataResource

Classification: VIRAL PROTEIN
Organism(s): African swine fever virus
Mutation(s): No

Deposited: 2024-03-20 Released: 2024-11-06
Deposition Author(s): Feng, X.Y.
Funding Organization(s): Not funded

Experimental Data Snapshot

Method: ELECTRON MICROSCOPY
Resolution: 2.68 Å
Aggregation State: PARTICLE
Reconstruction Method: SINGLE PARTICLE

wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

ASFV RNA polymerase-M1249L complex3

Feng, X.Y.

To be published.

Macromolecule Content

Total Structure Weight: 590.66 kDa
Atom Count: 36,029
Modelled Residue Count: 4,507
Deposited Residue Count: 5,176
Unique protein chains: 9

Macromolecules

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Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
DNA-directed RNA polymerase subunit	A	1,450	African swine fever virus	Mutation(s): 0 EC: 2.7.7.6
UniProt
Find proteins for P42486 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore P42486 Go to UniProtKB: P42486
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P42486
Sequence Annotations Expand
Reference Sequence LOADING

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Entity ID: 2
Molecule	Chains	Sequence Length	Organism	Details	Image
C147L	B [auth E]	147	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for P42484 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore P42484 Go to UniProtKB: P42484
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P42484
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Entity ID: 3
Molecule	Chains	Sequence Length	Organism	Details	Image
DNA-directed RNA polymerase subunit beta	C [auth B]	1,242	African swine fever virus	Mutation(s): 0 EC: 2.7.7.6
UniProt
Find proteins for P42487 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore P42487 Go to UniProtKB: P42487
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P42487
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Reference Sequence LOADING

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Entity ID: 4
Molecule	Chains	Sequence Length	Organism	Details	Image
DNA-directed RNA polymerase RPB3-11 homolog	D [auth C]	359	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for Q65184 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore Q65184 Go to UniProtKB: Q65184
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q65184
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Entity ID: 5
Molecule	Chains	Sequence Length	Organism	Details	Image
DNA-directed RNA polymerase RPB5 homolog	E [auth D]	205	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for Q65181 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore Q65181 Go to UniProtKB: Q65181
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q65181
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Entity ID: 6
Molecule	Chains	Sequence Length	Organism	Details	Image
DNA-directed RNA polymerase RPB10 homolog	F [auth H]	80	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for P42488 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore P42488 Go to UniProtKB: P42488
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P42488
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Entity ID: 7
Molecule	Chains	Sequence Length	Organism	Details	Image
C122R	G	105	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for Q65157 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore Q65157 Go to UniProtKB: Q65157
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q65157
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Entity ID: 8
Molecule	Chains	Sequence Length	Organism	Details	Image
M1249L	H [auth J]	1,249	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for Q65152 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore Q65152 Go to UniProtKB: Q65152
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q65152
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Entity ID: 9
Molecule	Chains	Sequence Length	Organism	Details	Image
D339L	I [auth F]	339	African swine fever virus	Mutation(s): 0
UniProt
Find proteins for Q89907 (African swine fever virus (strain Badajoz 1971 Vero-adapted)) Explore Q89907 Go to UniProtKB: Q89907
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q89907
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Reference Sequence LOADING

Small Molecules

Ligands 2 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
ZN Query on ZN Download Ideal Coordinates CCD File SDF format, chain S [auth J] SDF format, chain K [auth A] SDF format, chain L [auth A] SDF format, chain M [auth A] SDF format, chain N [auth B] SDF format, chain O [auth H] SDF format, chain P [auth G] SDF format, chain Q [auth G] SDF format, chain R [auth J] MOL2 format, chain S [auth J] MOL2 format, chain K [auth A] MOL2 format, chain L [auth A] MOL2 format, chain M [auth A] MOL2 format, chain N [auth B] MOL2 format, chain O [auth H] MOL2 format, chain P [auth G] MOL2 format, chain Q [auth G] MOL2 format, chain R [auth J] mmCIF format, chain S [auth J] mmCIF format, chain K [auth A] mmCIF format, chain L [auth A] mmCIF format, chain M [auth A] mmCIF format, chain N [auth B] mmCIF format, chain O [auth H] mmCIF format, chain P [auth G] mmCIF format, chain Q [auth G] mmCIF format, chain R [auth J]	K [auth A] L [auth A] M [auth A] N [auth B] O [auth H] K [auth A], L [auth A], M [auth A], N [auth B], O [auth H], P [auth G], Q [auth G], R [auth J], S [auth J]	ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N		Interactions Focus chain K [auth A] Focus chain L [auth A] Focus chain M [auth A] Focus chain N [auth B] Focus chain O [auth H] Focus chain P [auth G] Focus chain Q [auth G] Focus chain R [auth J] Focus chain S [auth J] Interactions & Density Focus chain K [auth A] Focus chain L [auth A] Focus chain M [auth A] Focus chain N [auth B] Focus chain O [auth H] Focus chain P [auth G] Focus chain Q [auth G] Focus chain R [auth J] Focus chain S [auth J]
MG Query on MG Download Ideal Coordinates CCD File SDF format, chain J [auth A] MOL2 format, chain J [auth A] mmCIF format, chain J [auth A]	J [auth A]	MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N		Interactions Focus chain J [auth A] Interactions & Density Focus chain J [auth A]