Download MendeleyMonitoring influence of pH on the molecular and crystal structure of hen egg-white tetragonal lysozyme
Lagziel-Simis, S., Wine, Y., Cohen-Hadar, N., Freeman, A., Frolow, F.To be published.
2HUB
Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5
- PDB DOI: https://doi.org/10.2210/pdb2HUB/pdb
- Classification: HYDROLASE
- Organism(s): Gallus gallus
- Mutation(s): No
- Deposited: 2006-07-26 Released: 2007-07-24
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.20 Å
- R-Value Free: 0.173
- R-Value Work: 0.137
- R-Value Observed: 0.138
Starting Model: other
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wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Lysozyme C | 129 | Gallus gallus | Mutation(s): 0 EC: 3.2.1.17 |  | |
UniProt | |||||
Find proteins for P00698 (Gallus gallus) Explore P00698 Go to UniProtKB: P00698 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00698 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 6 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EPE Query on EPE | D [auth A] | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID C8 H18 N2 O4 S JKMHFZQWWAIEOD-UHFFFAOYSA-N |  | ||
| TAR Query on TAR | F [auth A] | D(-)-TARTARIC ACID C4 H6 O6 FEWJPZIEWOKRBE-LWMBPPNESA-N |  | ||
| PPI Query on PPI | E [auth A] | PROPANOIC ACID C3 H6 O2 XBDQKXXYIPTUBI-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | C [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| FMT Query on FMT | G [auth A] | FORMIC ACID C H2 O2 BDAGIHXWWSANSR-UHFFFAOYSA-N |  | ||
| NA Query on NA | B [auth A] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.20 Å
- R-Value Free: 0.173
- R-Value Work: 0.137
- R-Value Observed: 0.138
- Space Group: P 43 21 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 76.861 | α = 90 |
| b = 76.861 | β = 90 |
| c = 35.867 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2007-07-24 Deposition Author(s): Frolow, F., Lagziel-Simis, S., Cohen-Hadar, N., Wine, Y., Freeman, A.
Revision History (Full details and data files)
- Version 1.0: 2007-07-24
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2017-10-18
Changes: Advisory, Refinement description - Version 1.4: 2024-04-03
Changes: Advisory, Data collection, Database references, Derived calculations, Refinement description - Version 1.5: 2024-11-20
Changes: Structure summary
