4J6I | pdb_00004j6i

Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform

CHAIN

A

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform - Homo sapiens

Explore Sequence Annotations in 3D

CHAIN A

UNIPROT P48736

SECONDARY STRUCTURE

UNMODELED

PLANE OUTLIERS

EDS ATOMS

OCC WT AVG B

AVERAGE OCCUPANCY

ATOMIC CLASHES

ANGLE OUTLIERS

RSRZ

RSR

RSCC

CIS-PEPTIDE

BINDING SITE 1JV

BURIED RESIDUES

ARTIFACT

HYDROPATHY

DISORDER

DISORDERED BINDING

PFAM

CATH

SCOP

ECOD

MOLECULE PROCESSING

GENOME VARIANT

MODIFIED RESIDUE

MUTAGENESIS

CONFLICT

DOMAIN

REGION

LOADING 23%

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.