QUERY: Enzyme Classification Number = 2.4.2.10
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Search Summary This query matches 92 Structures.
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1 to 25 of 92 Structures
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1LH0 | pdb_00001lh0

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Crystal Structure of Salmonella typhimurium OMP Synthase in Complex with MGPRPP and Orotate

Fedorov, A.A., Panneerselvam, K., Shi, W., Grubmeyer, C., Almo, S.C.

(2012) Biochemistry 51: 4397-4405

Released2002-05-08
Method
X-RAY DIFFRACTION 2 Å
Organisms
Macromolecule
OMP synthase (protein)
Unique LigandsMG, ORO, PRP
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1OPR | pdb_00001opr

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THE CRYSTAL STRUCTURE OF THE OROTATE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH OROTATE AND ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE

Scapin, G., Sacchettini, J.C.

(1995) Biochemistry 34: 10744-10754

Released1996-01-06
Method
X-RAY DIFFRACTION 2.3 Å
Organisms
Macromolecule
Unique LigandsMG, ORO, PRP
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1ORO | pdb_00001oro

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A FLEXIBLE LOOP AT THE DIMER INTERFACE IS A PART OF THE ACTIVE SITE OF THE ADJACENT MONOMER OF ESCHERICHIA COLI OROTATE PHOSPHORIBOSYLTRANSFERASE

Henriksen, A., Aghajari, N., Jensen, K.F., Gajhede, M.

(1996) Biochemistry 35: 3803-3809

Released1996-04-03
Method
X-RAY DIFFRACTION 2.4 Å
Organisms
Macromolecule
Unique LigandsSO4
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1STO | pdb_00001sto

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CRYSTAL STRUCTURE OF OROTATE PHOSPHORIBOSYLTRANSFERASE

Scapin, G., Grubmeyer, C., Sacchettini, J.C.

(1994) Biochemistry 33: 1287-1294

Released1994-05-31
Method
X-RAY DIFFRACTION 2.6 Å
Organisms
Macromolecule
Unique LigandsOMP
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2AEE | pdb_00002aee

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Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes

Chang, C., Li, H., Collart, F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)

To be published

Released2005-09-06
Method
X-RAY DIFFRACTION 1.95 Å
Organisms
Macromolecule
Unique LigandsCL, GOL, SO4
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2EAW | pdb_00002eaw

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Human UMP Synthase (C-terminal Domain- Orotidine 5'-Monophosphate Decarboxylase)

Liu, Y., Tang, H.L., Pai, E.F.

To be published

Released2007-02-13
Method
X-RAY DIFFRACTION 2.88 Å
Organisms
Macromolecule
Unique LigandsSO4
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2JGY | pdb_00002jgy

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The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)

Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released2007-03-06
Method
X-RAY DIFFRACTION 1.95 Å
Organisms
Macromolecule
UMP SYNTHASE (protein)
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2P1F | pdb_00002p1f

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Human UMP Synthase (C-terminal Domain-Orotidine 5'-Monophosphate Decarboxylase)

Liu, Y., Tang, H.L., Pai, E.F.

To be published

Released2007-04-03
Method
X-RAY DIFFRACTION 1.76 Å
Organisms
Macromolecule
Unique LigandsGOL, NA, SO4
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2P1Z | pdb_00002p1z

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Crystal structure of phosphoribosyltransferase from Corynebacterium diphtheriae

Chang, C., Li, H., Clancy, S., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)

To be published

Released2007-04-03
Method
X-RAY DIFFRACTION 2.44 Å
Organisms
Macromolecule
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2PRY | pdb_00002pry

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Apo form of S. cerevisiae orotate phosphoribosyltransferase

Gonzalez-Segura, L., Hurley, T.D., McClard, R.W.

(2007) Biochemistry 46: 14075-14086

Released2008-01-15
Method
X-RAY DIFFRACTION 2.35 Å
Organisms
Macromolecule
Unique LigandsMG
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2PRZ | pdb_00002prz

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S. cerevisiae orotate phosphoribosyltransferase complexed with OMP

Gonzalez-Segura, L., Hurley, T.D., McClard, R.W.

(2007) Biochemistry 46: 14075-14086

Released2008-01-15
Method
X-RAY DIFFRACTION 1.895 Å
Organisms
Macromolecule
Unique LigandsCL, OMP
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2PS1 | pdb_00002ps1

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S. cerevisiae orotate phosphoribosyltransferase complexed with orotic acid and PRPP

Gonzalez-Segura, L., Hurley, T.D., McClard, R.W.

(2007) Biochemistry 46: 14075-14086

Released2008-01-15
Method
X-RAY DIFFRACTION 1.75 Å
Organisms
Macromolecule
Unique LigandsMG, ORO, PRP
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2QCC | pdb_00002qcc

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsGOL, SO4
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2QCD | pdb_00002qcd

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 2.03 Å
Organisms
Macromolecule
Unique LigandsU5P
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2QCE | pdb_00002qce

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to sulfate, glycerol, and chloride

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.43 Å
Organisms
Macromolecule
Unique LigandsCL, GOL, SO4
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2QCF | pdb_00002qcf

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.22 Å
Organisms
Macromolecule
Unique Ligands5FU, GOL
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2QCG | pdb_00002qcg

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-bromo-UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.75 Å
Organisms
Macromolecule
Unique Ligands5BU
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2QCH | pdb_00002qch

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.95 Å
Organisms
Macromolecule
Unique Ligands5IU, IOD, UMP
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2QCL | pdb_00002qcl

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsGOL, OMP
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2QCM | pdb_00002qcm

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-06
Method
X-RAY DIFFRACTION 1.67 Å
Organisms
Macromolecule
Unique LigandsJW5
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2QCN | pdb_00002qcn

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Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP

Wittmann, J., Rudolph, M.

(2008) Structure 16: 82-92

Released2007-11-13
Method
X-RAY DIFFRACTION 1.85 Å
Organisms
Macromolecule
Unique LigandsGOL, SO4, U5P
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2V30 | pdb_00002v30

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Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.

Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released2007-07-24
Method
X-RAY DIFFRACTION 2 Å
Organisms
Macromolecule
Unique LigandsU5P
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2WNS | pdb_00002wns

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Human Orotate phosphoribosyltransferase (OPRTase) domain of Uridine 5' -monophosphate synthase (UMPS) in complex with its substrate orotidine 5'-monophosphate (OMP)

Moche, M., Roos, A., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotyenova, T., Kotzch, A., Nielsen, T.K., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Schutz, P., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., VanDenBerg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P.

To be published

Released2009-08-11
Method
X-RAY DIFFRACTION 1.9 Å
Organisms
Macromolecule
Unique LigandsCL, OMP
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2YZK | pdb_00002yzk

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Crystal structure of orotate phosphoribosyltransferase from Aeropyrum pernix

Kanagawa, M., Baba, S., Kuramitsu, S., Yokoyama, S., Kawai, G., Sampei, G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

To be published

Released2007-11-06
Method
X-RAY DIFFRACTION 1.8 Å
Organisms
Macromolecule
Unique LigandsPO4
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3BGG | pdb_00003bgg

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Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP

Liu, Y., Tang, H.L., Wang, X.Y., Kotra, L.P., Pai, E.F.

To be published

Released2007-12-11
Method
X-RAY DIFFRACTION 1.93 Å
Organisms
Macromolecule
Unique LigandsBMP
1 to 25 of 92 Structures
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