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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "PF1706"

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Search Summary

This query matches 19 Structures.

Refinements

Structure Determination Methodology

experimental (19)

Scientific Name of Source Organism

	Pyrococcus furiosus DSM 3638 (16)
	Pyrococcus furiosus (3)

Taxonomy

Archaea (19)

Experimental Method

X-RAY DIFFRACTION (19)

Polymer Entity Type

Protein (19)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (11)
	2.0 - 2.5 (6)
	2.5 - 3.0 (1)

Release Date

	2015 - 2019 (16)
	2020 - 2024 (3)

Enzyme Classification Name

Lyases (19)

Symmetry Type

Cyclic (19)

SCOP Classification

	Alpha and beta proteins (a/b) (16)
	Artifacts (4)

AllSelected

1 to 19 of 19 Structures

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Explore in 3D

5DVZ \| pdb_00005dvz	Download File View File

Holo TrpB from Pyrococcus furiosus

Buller, A.R., Arnold, F.H.

(2015) Proc Natl Acad Sci U S A 112: 14599-14604

Released	2016-02-03
Method	X-RAY DIFFRACTION 1.69 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PO4

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5DW0 \| pdb_00005dw0	Download File View File

TrpB from Pyrococcus furiosus with L-serine bound as the external aldimine

Buller, A.R., Arnold, F.H.

(2015) Proc Natl Acad Sci U S A 112: 14599-14604

Released	2015-11-11
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PLS

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5DW3 \| pdb_00005dw3	Download File View File

Tryptophan Synthase beta-subunit from Pyrococcus furiosus with product L-tryptophan non-covalently bound in the active site

Buller, A.R., Arnold, F.H.

(2015) Proc Natl Acad Sci U S A 112: 14599-14604

Released	2015-11-11
Method	X-RAY DIFFRACTION 1.74 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PO4, TRP

Explore in 3D

5E0K \| pdb_00005e0k	Download File View File

X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A

Buller, A.R., Murciano-Calles, J., Arnold, F.H.

(2015) Proc Natl Acad Sci U S A 112: 14599-14604

Released	2015-11-11
Method	X-RAY DIFFRACTION 2.76 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase alpha chain (protein) Tryptophan synthase beta chain 1 (protein)
Unique Ligands	PO4

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5IXJ \| pdb_00005ixj	Download File View File

Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site

Buller, A.R., Herger, M., Arnold, F.H.

(2016) J Am Chem Soc 138: 8388-8391

Released	2016-08-17
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, THR

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5T6M \| pdb_00005t6m	Download File View File

Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound

Buller, A.R., van Roye, P., Arnold, F.H.

(2016) Biochemistry 55: 7043-7046

Released	2016-12-21
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Pyrococcus furiosus
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	78U, NA, PO4

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5VM5 \| pdb_00005vm5	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser bound

Buller, A.R., van Roye, P.

(2018) J Am Chem Soc 140: 7256-7266

Released	2017-05-24
Method	X-RAY DIFFRACTION 1.67 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	0JO, NA, PLS

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6AM7 \| pdb_00006am7	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9

Buller, A.R., van Roye, P.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.47 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PO4

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6AM8 \| pdb_00006am8	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 with Trp bound as E(Aex2)

Buller, A.R., van Roye, P.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PLT, TRP

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6AM9 \| pdb_00006am9	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser-bound in a predominantly closed state.

Buller, A.R., van Roye, P.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 2.09 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	0JO, NA, PLS

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6AMC \| pdb_00006amc	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11

Buller, A.R., Herger, M.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA

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6AMH \| pdb_00006amh	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Ser bound as E(Aex1)

Buller, A.R.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.63 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PLS

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6AMI \| pdb_00006ami	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Trp non-covalently bound

Buller, A.R.

(2018) J Am Chem Soc 140: 7256-7266

Released	2018-05-16
Method	X-RAY DIFFRACTION 1.97 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, TRP

Explore in 3D

6CUT \| pdb_00006cut	Download File View File

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine

Boville, C.E., Scheele, R.A., Buller, A.R., Arnold, F.H.

(2018) Angew Chem Int Ed Engl 57: 14764-14768

Released	2018-09-26
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	FEJ, NA

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6CUV \| pdb_00006cuv	Download File View File

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6

Scheele, R.A., Buller, A.R., Boville, C.E., Arnold, F.H.

(2018) Angew Chem Int Ed Engl 57: 14764-14768

Released	2018-09-26
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PO4

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6CUZ \| pdb_00006cuz	Download File View File

Engineered TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3R)-ethylserine bound as the amino-acrylate

Scheele, R.A., Buller, A.R., Boville, C.E., Arnold, F.H.

(2018) Angew Chem Int Ed Engl 57: 14764-14768

Released	2018-09-26
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	FEV, NA, PO4

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7RNP \| pdb_00007rnp	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9_H275E with 4-Cl-Trp non-covalently bound

Higgins, P.M., Buller, A.R.

(2022) Nat Commun 13: 5242-5242

Released	2022-08-03
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Pyrococcus furiosus DSM 3638
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	6G5, NA

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7RNQ \| pdb_00007rnq	Download File View File

Holo structure of engineered TrpB, 2B9-H275E, from Pyrococcus furiosus in the extended-open conformation

Higgins, P.M., Buller, A.R.

(2022) Nat Commun 13: 5242-5242

Released	2022-08-03
Method	X-RAY DIFFRACTION 2.102 Å
Organisms	Pyrococcus furiosus
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, PO4

Explore in 3D

7ROF \| pdb_00007rof	Download File View File

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9-H275E with L-Trp non-covalently bound

Higgins, P.M., Buller, A.R.

(2022) Nat Commun 13: 5242-5242

Released	2022-08-03
Method	X-RAY DIFFRACTION 2.39 Å
Organisms	Pyrococcus furiosus
Macromolecule	Tryptophan synthase beta chain 1 (protein)
Unique Ligands	NA, TRP

1 to 19 of 19 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

5DVZ | pdb_00005dvz

Holo TrpB from Pyrococcus furiosus

5DW0 | pdb_00005dw0

TrpB from Pyrococcus furiosus with L-serine bound as the external aldimine

5DW3 | pdb_00005dw3

Tryptophan Synthase beta-subunit from Pyrococcus furiosus with product L-tryptophan non-covalently bound in the active site

5E0K | pdb_00005e0k

X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A

5IXJ | pdb_00005ixj

Tryptophan Synthase beta-subunit from Pyrococcus furiosus with L-threonine non-covalently bound in the active site

5T6M | pdb_00005t6m

Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound

5VM5 | pdb_00005vm5

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser bound

6AM7 | pdb_00006am7

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9

6AM8 | pdb_00006am8

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 with Trp bound as E(Aex2)

6AM9 | pdb_00006am9

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser-bound in a predominantly closed state.

6AMC | pdb_00006amc

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11

6AMH | pdb_00006amh

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Ser bound as E(Aex1)

6AMI | pdb_00006ami

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Trp non-covalently bound

6CUT | pdb_00006cut

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine

6CUV | pdb_00006cuv

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6

6CUZ | pdb_00006cuz

Engineered TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3R)-ethylserine bound as the amino-acrylate

7RNP | pdb_00007rnp

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9_H275E with 4-Cl-Trp non-covalently bound

7RNQ | pdb_00007rnq

Holo structure of engineered TrpB, 2B9-H275E, from Pyrococcus furiosus in the extended-open conformation

7ROF | pdb_00007rof

Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9-H275E with L-Trp non-covalently bound

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

5DVZ | pdb_00005dvz

5DW0 | pdb_00005dw0

5DW3 | pdb_00005dw3

5E0K | pdb_00005e0k

5IXJ | pdb_00005ixj

5T6M | pdb_00005t6m

5VM5 | pdb_00005vm5

6AM7 | pdb_00006am7

6AM8 | pdb_00006am8

6AM9 | pdb_00006am9

6AMC | pdb_00006amc

6AMH | pdb_00006amh

6AMI | pdb_00006ami

6CUT | pdb_00006cut

6CUV | pdb_00006cuv

6CUZ | pdb_00006cuz

7RNP | pdb_00007rnp

7RNQ | pdb_00007rnq

7ROF | pdb_00007rof