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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Sansom, M.S."

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Search Summary

This query matches 18 Structures.

Refinements

Structure Determination Methodology

experimental (18)

Scientific Name of Source Organism

	Homo sapiens (5)
	Escherichia coli (4)
	Microbacterium maritypicum (4)
	Arabidopsis thaliana (2)
	Escherichia coli K-12 (2)
	Mus musculus (1)
	Neisseria gonorrhoeae FA 1090 (1)
	Paramagnetospirillum magnetotacticum (1)

Taxonomy

	Bacteria (12)
	Eukaryota (8)

Experimental Method

	X-RAY DIFFRACTION (14)
	ELECTRON MICROSCOPY (2)
	SOLUTION NMR (2)

Polymer Entity Type

Protein (18)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (2)
	3.0 - 3.5 (4)
	3.5 - 4.0 (9)

Release Date

	2005 - 2009 (1)
	2010 - 2014 (9)
	2015 - 2019 (8)

Enzyme Classification Name

	Hydrolases (1)
	Translocases (1)

Membrane Protein Annotation

	PDBTM (16)
	MemProtMD (15)
	mpstruc (13)
	OPM (9)

Symmetry Type

	Cyclic (10)
	Asymmetric (8)

SCOP Classification

	All beta proteins (1)
	Artifacts (1)
	Membrane and cell surface proteins and peptides (1)

AllSelected

1 to 18 of 18 Structures

Page 1 of 1

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2LZR \| pdb_00002lzr	Download File View File

TatA T22P

Rodriguez, F.M., Berks, B.C., Schnell, J.R.

(2013) Proc Natl Acad Sci U S A 110: E1092-E1101

Released	2013-03-20
Method	SOLUTION NMR
Organisms	Escherichia coli K-12
Macromolecule	Sec-independent protein translocase protein TatA (protein)

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2LZS \| pdb_00002lzs	Download File View File

TatA oligomer

Rodriguez, F.M., Berks, B.C., Schnell, J.R.

(2013) Proc Natl Acad Sci U S A 110: E1092-E1101

Released	2013-03-20
Method	SOLUTION NMR
Organisms	Escherichia coli K-12
Macromolecule	Sec-independent protein translocase protein TatA (protein)

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3FVQ \| pdb_00003fvq	Download File View File

Crystal structure of the nucleotide binding domain FbpC complexed with ATP

Newstead, S., Bilton, P., Carpenter, E.P., Campopiano, D., Iwata, S.

(2009) Structure 17: 1213-1222

Released	2009-08-25
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Neisseria gonorrhoeae FA 1090
Macromolecule	Fe(3+) ions import ATP-binding protein fbpC (protein)
Unique Ligands	ATP, CA

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4ATV \| pdb_00004atv	Download File View File

STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH

Drew, D., Lee, C., Iwata, S., Cameron, A.D.

(2014) J Gen Physiol 144: 529-544

Released	2013-07-10
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Escherichia coli
Macromolecule	NA(+)/H(+) ANTIPORTER NHAA (protein)
Unique Ligands	LMU, SO4

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4AU5 \| pdb_00004au5	Download File View File

Structure of the NhaA dimer, crystallised at low pH

Drew, D., Lee, C., Iwata, S., Cameron, A.D.

(2014) J Gen Physiol 144: 529-544

Released	2013-07-10
Method	X-RAY DIFFRACTION 3.696 Å
Organisms	Escherichia coli
Macromolecule	NA(+)/H(+) ANTIPORTER NHAA (protein)
Unique Ligands	LMU, SO4

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4D1A \| pdb_00004d1a	Download File View File

STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN

Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.

(2014) EMBO J 33: 1831

Released	2014-07-02
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Microbacterium maritypicum
Macromolecule	HYDANTOIN TRANSPORT PROTEIN (protein)
Unique Ligands	I5H, NA

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4D1B \| pdb_00004d1b	Download File View File

STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN

Brueckner, F., Geng, T., Weyand, S., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.

(2014) EMBO J 33: 1831

Released	2014-07-02
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Microbacterium maritypicum
Macromolecule	HYDANTOIN TRANSPORT PROTEIN (protein)
Unique Ligands	5FH, NA

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4D1C \| pdb_00004d1c	Download File View File

STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH bromovinylhydantoin bound.

Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.

(2014) EMBO J 33: 1831

Released	2014-07-02
Method	X-RAY DIFFRACTION 3.7 Å
Organisms	Microbacterium maritypicum
Macromolecule	HYDANTOIN TRANSPORT PROTEIN (protein)
Unique Ligands	B5H, NA

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4D1D \| pdb_00004d1d	Download File View File

STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER with the inhibitor 5-(2-naphthylmethyl)-L-hydantoin.

Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.

(2014) EMBO J 33: 1831

Released	2014-07-02
Method	X-RAY DIFFRACTION 3.7 Å
Organisms	Microbacterium maritypicum
Macromolecule	HYDANTOIN TRANSPORT PROTEIN (protein)
Unique Ligands	5ND, 5NL, NA

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4LP8 \| pdb_00004lp8	Download File View File

A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1

Zubcevic, L., Bavro, V.N., Muniz, J.R.C., Schmidt, M.R., Wang, S., De Zorzi, R., Venien-Bryan, C., Sansom, M.S.P., Nichols, C.G., Tucker, S.J.

(2014) J Biological Chem 289: 143-151

Released	2013-11-20
Method	X-RAY DIFFRACTION 2.46 Å
Organisms	Paramagnetospirillum magnetotacticum
Macromolecule	Inward rectifier potassium channel Kirbac3.1 (protein)
Unique Ligands	CL, K, PEG

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4XDJ \| pdb_00004xdj	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)

Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.8 Å
Organisms	Homo sapiens
Macromolecule	POTASSIUM CHANNEL SUBFAMILY K MEMBER 10 (protein)
Unique Ligands	K, PC1, TRD

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4XDK \| pdb_00004xdk	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine

Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.6 Å
Organisms	Homo sapiens
Macromolecule	Potassium channel subfamily K member 10 (protein)
Unique Ligands	405, 408, K, PC1

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4XDL \| pdb_00004xdl	Download File View File

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with a brominated fluoxetine derivative.

Mackenzie, A., Pike, A.C.W., Dong, Y.Y., Mukhopadhyay, S., Ruda, G.F., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)

(2015) Science 347: 1256-1259

Released	2015-03-18
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens
Macromolecule	Potassium channel subfamily K member 10 (protein)
Unique Ligands	40D, CD, K, PC1

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5L7D \| pdb_00005l7d	Download File View File

Structure of human Smoothened in complex with cholesterol

Byrne, E.F.X., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.P., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.

(2016) Nature 535: 517-522

Released	2016-07-20
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	Smoothened homolog,Soluble cytochrome b562,Smoothened homolog (protein)
Unique Ligands	CLR, NA, NAG

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5L7I \| pdb_00005l7i	Download File View File

Structure of human Smoothened in complex with Vismodegib

Byrne, E.X.B., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.F., Sansom, M.S.P., Newstead, S., Rohatgi, R., Siebold, C.

(2016) Nature 535: 517-522

Released	2016-07-20
Method	X-RAY DIFFRACTION 3.3 Å
Organisms	Escherichia coli Homo sapiens
Macromolecule	Smoothened homolog,Soluble cytochrome b562,Smoothened homolog (protein)
Unique Ligands	MPG, NA, NAG, VIS