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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Lu, H."

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Search Summary

This query matches 136 Structures.

Refinements

Structure Determination Methodology

experimental (136)

Scientific Name of Source Organism

	Homo sapiens (72)
	Human immunodeficiency virus 1 (11)
	Plasmodium falciparum Palo Alto/Uganda (7)
	Staphylococcus aureus (6)
	Severe acute respiratory syndrome coronavirus 2 (5)
	Zea mays (5)
	Yersinia pestis CO92 (4)
	Deinococcus geothermalis DSM 11300 (3)
	HIV-1 06TG.HT008 (3)
	Mus musculus (3)

More...

Taxonomy

	Eukaryota (98)
	Riboviria (24)
	Bacteria (23)
	other sequences (3)
	Duplodnaviria (2)

Experimental Method

	X-RAY DIFFRACTION (118)
	ELECTRON MICROSCOPY (15)
	SOLUTION NMR (3)

Polymer Entity Type

	Protein (136)
	DNA (3)
	RNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (9)
	1.5 - 2.0 (40)
	2.0 - 2.5 (47)
	2.5 - 3.0 (12)
	3.0 - 3.5 (11)
	3.5 - 4.0 (10)
	4.0 - 4.5 (1)
	> 4.5 (3)

Release Date

	1990 - 1994 (1)
	2000 - 2004 (4)
	2005 - 2009 (5)
	2010 - 2014 (22)
	2015 - 2019 (37)
	2020 - 2024 (66)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (47)
	Oxidoreductases (20)
	Hydrolases (28)
	Lyases (3)

Membrane Protein Annotation

	PDBTM (5)
	MemProtMD (4)
	mpstruc (1)

Symmetry Type

	Asymmetric (97)
	Cyclic (32)
	Dihedral (8)

SCOP Classification

	Alpha and beta proteins (a/b) (19)
	Alpha and beta proteins (a+b) (22)
	All alpha proteins (8)
	Artifacts (7)
	All beta proteins (3)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 136 Structures

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1MN6 \| pdb_00001mn6	Download File View File

Thioesterase Domain from Picromycin Polyketide Synthase, pH 7.6

Tsai, S.-C., Lu, H., Cane, D.E., Khosla, C., Stroud, R.M.

(2002) Biochemistry 41: 12598-12606

Released	2003-02-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Streptomyces venezuelae
Macromolecule	polyketide synthase IV (protein)

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1MNA \| pdb_00001mna	Download File View File

Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.0

Tsai, S.-C., Lu, H., Cane, D.E., Khosla, C., Stroud, R.M.

(2002) Biochemistry 41: 12598-12606

Released	2003-02-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Streptomyces venezuelae
Macromolecule	polyketide synthase IV (protein)

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1MNQ \| pdb_00001mnq	Download File View File

Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.4

Tsai, S.-C., Lu, H., Cane, D.E., Khosla, C., Stroud, R.M.

(2002) Biochemistry 41: 12598-12606

Released	2003-02-04
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Streptomyces venezuelae
Macromolecule	polyketide synthase IV (protein)

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1MO2 \| pdb_00001mo2	Download File View File

Thioesterase Domain from 6-Deoxyerythronolide Synthase (DEBS TE), pH 8.5

Tsai, S.-C., Lu, H., Cane, D.E., Khosla, C., Stroud, R.M.

(2002) Biochemistry 41: 12598-12606

Released	2003-02-04
Method	X-RAY DIFFRACTION 3 Å
Organisms	Saccharopolyspora erythraea
Macromolecule	Erythronolide synthase, modules 5 and 6 (protein)

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1RHG \| pdb_00001rhg	Download File View File

THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS

Hill, C.P., Osslund, T.D., Eisenberg, D.

(1993) Proc Natl Acad Sci U S A 90: 5167-5171

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	GRANULOCYTE COLONY-STIMULATING FACTOR (protein)

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2EUF \| pdb_00002euf	Download File View File

X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991

Schulze-Gahmen, U., Lu, H.

(2006) J Med Chem 49: 3826-3831

Released	2006-07-04
Method	X-RAY DIFFRACTION 3 Å
Organisms	Herpesvirus saimiri (strain 11) Homo sapiens
Macromolecule	Cell division protein kinase 6 (protein) viral Cyclin (protein)
Unique Ligands	ACT, CA, DMS, LQQ

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2F2C \| pdb_00002f2c	Download File View File

X-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanol

Schulze-Gahmen, U., Lu, H.

(2006) J Med Chem 49: 3826-3831

Released	2006-06-13
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Herpesvirus saimiri (strain 11) Homo sapiens
Macromolecule	Cell division protein kinase 6 (protein) Cyclin homolog (protein)
Unique Ligands	AP9, DMS, SO4

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2HY8 \| pdb_00002hy8	Download File View File

PAK1 complex with ST2001

Schulze-Gahmen, U., Lu, H.

To be published

Released	2006-11-07
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase PAK 1 (protein)
Unique Ligands	1ST

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2JJY \| pdb_00002jjy	Download File View File

Crystal structure of Francisella tularensis enoyl reductase (ftFabI) with bound NAD

Luckner, S.R., Lu, H., Truglio, J.J., Tonge, P.J., Kisker, C.

(2009) ACS Chem Biol 4: 221

Released	2009-02-24
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Francisella tularensis
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE (protein)
Unique Ligands	NAD

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2JNR \| pdb_00002jnr	Download File View File

Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide

Munch, J., Standker, L., Adermann, K., Schulz, A., Pohlmann, S., Chaipan, C., Biet, T., Peters, T., Meyer, B., Wilhelm, D., Lu, H., Jing, W., Jiang, S., Forssmann, W., Kirchhoff, F.

(2007) Cell 129: 263-275

Released	2007-05-08
Method	SOLUTION NMR
Organisms	synthetic construct
Macromolecule	ENV polyprotein (protein) VIR165 (protein)

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2L6S \| pdb_00002l6s	Download File View File

Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide

Forssmann, W., The, Y., Stoll, M., Adermann, K., Albrecht, U., Barlos, K., Busmann, A., Canales-Mayordomo, A., Gimenez-Gallego, G., Hirsch, J., Jimenez-Barbero, J., Meyer-Olson, D., Muench, J., Perez-Castells, J., Standker, L., Kirchhoff, F., Schmidt, R.E.

(2010) Sci Transl Med 2: 63re3-63re3

Released	2011-01-19
Method	SOLUTION NMR
Macromolecule	VIR-576 (protein)

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2L6T \| pdb_00002l6t	Download File View File

Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide

Forssmann, W., The, Y., Stoll, M., Adermann, K., Albrecht, U., Barlos, K., Busmann, A., Can les-Mayordomo, A., Gimenez-Gallego, G., Hirsch, J., Jimenez-Barbero, J., Meyer-Olson, D., Muench, J., Perez-Castells, J., Staendker, L., Kirchhoff, F., Schmidt, R.E.

(2010) Sci Transl Med 2: 63re3-63re3

Released	2011-01-19
Method	SOLUTION NMR
Macromolecule	VIR-576 (protein)

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3ZU2 \| pdb_00003zu2	Download File View File

Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH (SIRAS)

Hirschbeck, M.W., Kuper, J., Kisker, C.

(2012) Structure 20: 89

Released	2012-01-18
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Yersinia pestis CO92
Macromolecule	PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011 (protein)
Unique Ligands	NA, NAI

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3ZU3 \| pdb_00003zu3	Download File View File

Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH (MR, cleaved Histag)

Hirschbeck, M.W., Kuper, J., Kisker, C.

(2012) Structure 20: 89

Released	2012-01-18
Method	X-RAY DIFFRACTION 1.802 Å
Organisms	Yersinia pestis CO92
Macromolecule	PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011 (protein)
Unique Ligands	GOL, NA, NAI

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3ZU4 \| pdb_00003zu4	Download File View File

Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH and the 2-pyridone inhibitor PT172

Hirschbeck, M.W., Kuper, J., Tonge, P.J., Kisker, C.

(2012) Structure 20: 89

Released	2012-01-18
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Yersinia pestis CO92
Macromolecule	PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011 (protein)
Unique Ligands	NA, NAI, ZU4

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3ZU5 \| pdb_00003zu5	Download File View File

Structure of the enoyl-ACP reductase FabV from Yersinia pestis with the cofactor NADH and the 2-pyridone inhibitor PT173

Hirschbeck, M.W., Kuper, J., Tonge, P.J., Kisker, C.

(2012) Structure 20: 89

Released	2012-01-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Yersinia pestis CO92
Macromolecule	PUTATIVE REDUCTASE YPO4104/Y4119/YP_4011 (protein)
Unique Ligands	AEW, NA, NAI

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4ALI \| pdb_00004ali	Download File View File

Crystal structure of S. aureus FabI in complex with NADP and triclosan (P1)

Schiebel, J., Chang, A., Tonge, P.J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)
Unique Ligands	GLU, NAP, TCL

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4ALJ \| pdb_00004alj	Download File View File

Crystal structure of S. aureus FabI in complex with NADP and 5-chloro- 2-phenoxyphenol

Schiebel, J., Chang, A., Tonge, P.J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)
Unique Ligands	CH8, GLU, NAP

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4ALK \| pdb_00004alk	Download File View File

Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol

Schiebel, J., Chang, A., Tonge, P.J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)
Unique Ligands	E9P, GLU, NAP

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4ALL \| pdb_00004all	Download File View File

Crystal structure of S. aureus FabI in complex with NADP and triclosan (P212121)

Schiebel, J., Chang, A., Tonge, P.J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)
Unique Ligands	NAP, TCL

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4ALM \| pdb_00004alm	Download File View File

Crystal structure of S. aureus FabI (P43212)

Schiebel, J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)
Unique Ligands	SO4

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4ALN \| pdb_00004aln	Download File View File

Crystal structure of S. aureus FabI (P32)

Schiebel, J., Kisker, C.

(2012) Structure 20: 802

Released	2012-05-09
Method	X-RAY DIFFRACTION 3.05 Å
Organisms	Staphylococcus aureus
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH] (protein)

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4EWJ \| pdb_00004ewj	Download File View File

structure of the enloase from Streptococcus suis serotype 2

Lu, Q., Lu, H., Qi, J., Lu, G., Gao, G.F.

(2012) Protein Cell 3: 769-780

Released	2012-10-24
Method	X-RAY DIFFRACTION 2.403 Å
Organisms	Streptococcus suis
Macromolecule	Enolase 2 (protein)

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4GU1 \| pdb_00004gu1	Download File View File

Crystal structure of LSD2

Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.

(2013) Mol Cell 49: 558-570

Released	2013-01-16
Method	X-RAY DIFFRACTION 2.939 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific histone demethylase 1B (protein)
Unique Ligands	CL, FAD, NA, ZN

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4GUR \| pdb_00004gur	Download File View File

Crystal structure of LSD2-NPAC with H3 in space group P21

Chen, F., Dong, Z., Fang, J., Yang, Y., Li, Z., Xu, Y., Yang, H., Wang, P., Fang, R., Shi, Y., Xu, Y.

(2013) Mol Cell 49: 558-570

Released	2013-01-16
Method	X-RAY DIFFRACTION 2.506 Å
Organisms	Homo sapiens
Macromolecule	Histone H3.3 (protein) Lysine-specific histone demethylase 1B (protein) Putative oxidoreductase GLYR1 (protein)
Unique Ligands	FAD, GOL, ZN

1 to 25 of 136 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1MN6 | pdb_00001mn6

1MNA | pdb_00001mna

1MNQ | pdb_00001mnq

1MO2 | pdb_00001mo2

1RHG | pdb_00001rhg

2EUF | pdb_00002euf

2F2C | pdb_00002f2c

2HY8 | pdb_00002hy8

2JJY | pdb_00002jjy

2JNR | pdb_00002jnr

2L6S | pdb_00002l6s

2L6T | pdb_00002l6t

3ZU2 | pdb_00003zu2

3ZU3 | pdb_00003zu3

3ZU4 | pdb_00003zu4

3ZU5 | pdb_00003zu5

4ALI | pdb_00004ali

4ALJ | pdb_00004alj

4ALK | pdb_00004alk

4ALL | pdb_00004all

4ALM | pdb_00004alm

4ALN | pdb_00004aln

4EWJ | pdb_00004ewj

4GU1 | pdb_00004gu1

4GUR | pdb_00004gur