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234,785 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Zon, G."

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Search Summary

This query matches 37 Structures.

Refinements

Structure Determination Methodology

experimental (37)

Scientific Name of Source Organism

	Homo sapiens (16)
	Escherichia phage Lambda (5)
	Neisseria meningitidis MC58 (5)
	Saccharomyces cerevisiae S288C (5)
	Nakaseomyces glabratus CBS 138 (3)
	Tequatrovirus T4 (2)
	Vibrio vulnificus MO6-24/O (2)
	Arabidopsis thaliana (1)
	Lachancea thermotolerans CBS 6340 (1)
	Nakaseomyces glabratus (1)

More...

Taxonomy

	Eukaryota (27)
	Bacteria (8)
	Duplodnaviria (7)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (32)
	ELECTRON MICROSCOPY (5)

Polymer Entity Type

Protein (37)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (2)
	2.0 - 2.5 (14)
	2.5 - 3.0 (8)
	3.0 - 3.5 (8)
	3.5 - 4.0 (2)
	4.0 - 4.5 (1)

Release Date

	2010 - 2014 (8)
	2015 - 2019 (3)
	2020 - 2024 (25)
	2025 - 2029 (1)

Enzyme Classification Name

	Hydrolases (7)
	Transferases (7)

Membrane Protein Annotation

	OPM (1)
	PDBTM (1)
	mpstruc (1)

Symmetry Type

	Asymmetric (24)
	Cyclic (12)
	Dihedral (2)

SCOP Classification

	Alpha and beta proteins (a+b) (5)
	Artifacts (1)
	Membrane and cell surface proteins and peptides (1)

AllSelected

1 to 25 of 37 Structures

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4AYD \| pdb_00004ayd	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 R106A mutant

Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)
Unique Ligands	EDO

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4AYE \| pdb_00004aye	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 E283AE304A mutant

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)
Unique Ligands	EDO

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4AYI \| pdb_00004ayi	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 Wild type

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.31 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) LIPOPROTEIN GNA1870 CCOMPND 7 (protein)
Unique Ligands	EDO

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4AYM \| pdb_00004aym	Download File View File

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 P106A mutant

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Neisseria meningitidis MC58
Macromolecule	COMPLEMENT FACTOR H (protein) FACTOR H BINDING PROTEIN (protein)

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4AYN \| pdb_00004ayn	Download File View File

Structure of the C-terminal barrel of Neisseria meningitidis FHbp Variant 2

(2012) PLoS Pathog 8: 2981

Released	2012-11-07
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Neisseria meningitidis MC58
Macromolecule	FACTOR H-BINDING PROTEIN (protein)
Unique Ligands	SO4

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4L3I \| pdb_00004l3i	Download File View File

Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)

Subramanian, R., Ti, S., Tan, L., Darst, S.A., Kapoor, T.M.

(2013) Cell 154: 377-390

Released	2013-07-17
Method	X-RAY DIFFRACTION 3.6005 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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4L6Y \| pdb_00004l6y	Download File View File

Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)

Subramanian, R., Ti, S., Tan, L., Darst, S.A., Kapoor, T.M.

(2013) Cell 154: 377-390

Released	2013-07-17
Method	X-RAY DIFFRACTION 3.3015 Å
Organisms	Homo sapiens
Macromolecule	Protein regulator of cytokinesis 1 (protein)

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4O91 \| pdb_00004o91	Download File View File

Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1

Gurbani, D., Hunter, J.C., Tan, L., Westover, K.D.

(2015) J Med Chem 58: 183-196

Released	2014-07-30
Method	X-RAY DIFFRACTION 2.393 Å
Organisms	Homo sapiens
Macromolecule	Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera (protein)
Unique Ligands	NG2

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4Z16 \| pdb_00004z16	Download File View File

Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)methyl)phenyl)acrylamide

McNally, R., Tan, L., Gray, N.S., Eck, M.J.

(2015) J Med Chem 58: 6589-6606

Released	2016-02-10
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Tyrosine-protein kinase JAK3 (protein)
Unique Ligands	4LH

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5E7R \| pdb_00005e7r	Download File View File

Crystal structure of TL10-81 bound to TAK1-TAB1

Gurbani, D., Hunter, J.C., Tan, L., Chen, Z., Westover, K.D.

(2017) Bioorg Med Chem 25: 838-846

Released	2016-09-21
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	TAK1 kinase - TAB1 chimera fusion protein (protein)
Unique Ligands	5KW

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6DAU \| pdb_00006dau	Download File View File

Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae

Filippova, E.V., Minasov, G., Beahan, A., Kulyavtsev, P., Tan, L., Tran, D., Kuhn, M.L., Anderson, W.F., Satchell, K.J.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)

To be published

Released	2018-07-04
Method	X-RAY DIFFRACTION 2.26 Å
Organisms	Vibrio cholerae O1 biovar El Tor
Macromolecule	Spermidine N1-acetyltransferase (protein)
Unique Ligands	GOL

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6LUQ \| pdb_00006luq	Download File View File

Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands

Fan, L., Tan, L., Chen, Z., Qi, J., Nie, F., Luo, Z., Cheng, J., Wang, S.

(2020) Nat Commun 11: 1074-1074

Released	2020-03-04
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Homo sapiens Tequatrovirus T4
Macromolecule	chimera of D(2) dopamine receptor and Endolysin (protein)
Unique Ligands	GMJ, OLA

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6YG3 \| pdb_00006yg3	Download File View File

Crystal structure of MKK7 (MAP2K7) covalently bound with CPT1-70-1

Chaikuad, A., Tan, L., Wang, J., Liang, Y., Gray, N.S., Knapp, S., Structural Genomics Consortium (SGC)

(2020) Cell Chem Biol 27: 1285-1295.e4

Released	2020-08-12
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 7 (protein)
Unique Ligands	6HF, EDO

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6YG6 \| pdb_00006yg6	Download File View File

Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor TL10-105

Chaikuad, A., Tan, L., Wang, J., Liang, Y., Gray, N.S., Knapp, S., Structural Genomics Consortium (SGC)

(2020) Cell Chem Biol 27: 1285-1295.e4

Released	2020-08-12
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 7 (protein)
Unique Ligands	EDO, OQ8

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6YG7 \| pdb_00006yg7	Download File View File

Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor SB1-G-23

Chaikuad, A., Tan, L., Wang, J., Liang, Y., Gray, N.S., Knapp, S., Structural Genomics Consortium (SGC)

(2020) Cell Chem Biol 27: 1285-1295.e4

Released	2020-08-12
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 7 (protein)
Unique Ligands	EDO, OQ2

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7DEI \| pdb_00007dei	Download File View File

Structure of human ORP3 ORD domain in complex with PI(4)P

Tong, J., Tan, L., Im, Y.J.

(2021) PLoS One 16: e0248781-e0248781

Released	2021-03-24
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Oxysterol-binding protein-related protein 3 (protein)
Unique Ligands	PIF

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7DEJ \| pdb_00007dej	Download File View File

Structure of human ORP3 ORD in apo-form

Tong, J., Tan, L., Im, Y.J.

(2021) PLoS One 16: e0248781-e0248781

Released	2021-03-24
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	Oxysterol-binding protein-related protein 3 (protein)

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7F6J \| pdb_00007f6j	Download File View File

Crystal structure of the PDZD8 coiled-coil domain - Rab7 complex

Khan, H., Chen, L., Tan, L., Im, Y.J.

(2021) Sci Rep 11: 18859-18859

Released	2022-02-23
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	PDZ domain-containing protein 8 (protein) Ras-related protein Rab-7a (protein)
Unique Ligands	GTP, MG

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7VPR \| pdb_00007vpr	Download File View File

Crystal structure of the ligand-binding domain of C. glabrata Upc2 in complex with ergosterol

Tan, L., Im, Y.J.

(2022) Nat Chem Biol 18: 1253-1262

Released	2022-09-07
Method	X-RAY DIFFRACTION 2.59 Å
Organisms	Nakaseomyces glabratus CBS 138
Macromolecule	Sterol uptake control protein 2 (Upc2) (protein)
Unique Ligands	ERG

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7VPS \| pdb_00007vps	Download File View File

Crystal structure of the ARM domain of C. glabrata importin alpha

Tan, L., Im, Y.J.

(2022) Nat Chem Biol 18: 1253-1262

Released	2022-09-07
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Nakaseomyces glabratus CBS 138
Macromolecule	Importin subunit alpha (protein)

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7VPT \| pdb_00007vpt	Download File View File

Structure of the C. glabrata importin alpha ARM domain - Upc2 NLS fusion

Tan, L., Im, Y.J.

(2022) Nat Chem Biol 18: 1253-1262

Released	2022-09-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Nakaseomyces glabratus CBS 138
Macromolecule	C. glabrata importin alpha ARM domain - Upc2 NLS fusion (protein)

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7VPU \| pdb_00007vpu	Download File View File

Crystal structure of the ligand-binding domain of L. thermotolerans Upc2 in complex with ergosterol

Tan, L., Im, Y.J.

(2022) Nat Chem Biol 18: 1253-1262

Released	2022-08-24
Method	X-RAY DIFFRACTION 2.59 Å
Organisms	Lachancea thermotolerans CBS 6340
Macromolecule	Sterol uptake control protein 2 (Upc2) (protein)
Unique Ligands	ERG

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7WVT \| pdb_00007wvt	Download File View File

Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol

Chen, L., Tan, L., Im, Y.J.

(2022) Acta Crystallogr D Struct Biol 78: 853-864

Released	2022-07-13
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Phosphatidylinositol transfer protein CSR1 (protein)
Unique Ligands	B7N

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7WWD \| pdb_00007wwd	Download File View File

Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with squalene

Chen, L., Tan, L., Im, Y.J.

(2022) Acta Crystallogr D Struct Biol 78: 853-864

Released	2022-07-13
Method	X-RAY DIFFRACTION 2.39 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Phosphatidylinositol transfer protein CSR1 (protein)
Unique Ligands	SQL

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7WWE \| pdb_00007wwe	Download File View File

Crystal structure of Saccharomyces cerevisiae Sfh2 in an apo form

Chen, L., Tan, L., Im, Y.J.

(2022) Acta Crystallogr D Struct Biol 78: 853-864

Released	2022-07-13
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Saccharomyces cerevisiae S288C
Macromolecule	Phosphatidylinositol transfer protein CSR1 (protein)

1 to 25 of 37 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

4AYD | pdb_00004ayd

4AYE | pdb_00004aye

4AYI | pdb_00004ayi

4AYM | pdb_00004aym

4AYN | pdb_00004ayn

4L3I | pdb_00004l3i

4L6Y | pdb_00004l6y

4O91 | pdb_00004o91

4Z16 | pdb_00004z16

5E7R | pdb_00005e7r

6DAU | pdb_00006dau

6LUQ | pdb_00006luq

6YG3 | pdb_00006yg3

6YG6 | pdb_00006yg6

6YG7 | pdb_00006yg7

7DEI | pdb_00007dei

7DEJ | pdb_00007dej

7F6J | pdb_00007f6j

7VPR | pdb_00007vpr

7VPS | pdb_00007vps

7VPT | pdb_00007vpt

7VPU | pdb_00007vpu

7WVT | pdb_00007wvt

7WWD | pdb_00007wwd

7WWE | pdb_00007wwe