Beta-2-microglobulin

UniProtKB accession: P61769

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Polymer Entities matching query 1,254

Go to UniProtKB: P61769

UniProtKB description: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).

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