8CHE

TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide

External Resource: Annotation


SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
A [auth H],
C [auth A]		Heavy ChainIGHV3 -trem-like transcript 1 proteinSAbDab (2024-12-13)
B [auth L],
D [auth B]		Light ChainIGKV2 Kappatrem-like transcript 1 proteinSAbDab (2024-12-13)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth H],
C [auth A]		Fab heavy chain---
B [auth L],
D [auth B]		Fab light chain---
E [auth C],
F [auth D]		Trem-like transcript 1 protein-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
E [auth C],
F [auth D]		IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
E [auth C],
F [auth D]		IPR013783Immunoglobulin-like foldHomologous Superfamily
E [auth C],
F [auth D]		IPR050671CD300 family immune receptorsFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
E [auth C],
F [auth D]		Pharos:  Q86YW5