7YXO
Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
C | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8094545 | 3001442 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8094545 | 3001442 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | Nuclear receptor ligand-binding domain | 8094545 | 3001442 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C | Hormone_recep | e7yxoC1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
A | Hormone_recep | e7yxoA1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
E | Hormone_recep | e7yxoE1 | A: alpha arrays | X: Nuclear receptor ligand-binding domain (From Topology) | H: Nuclear receptor ligand-binding domain (From Topology) | T: Nuclear receptor ligand-binding domain | F: Hormone_recep | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00104 | Ligand-binding domain of nuclear hormone receptor (Hormone_recep) | Ligand-binding domain of nuclear hormone receptor | This all helical domain is involved in binding the hormone in these receptors. | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001723 | Nuclear hormone receptor | Family | |
IPR000536 | Nuclear hormone receptor, ligand-binding domain | Domain | |
IPR035500 | Nuclear hormone receptor-like domain superfamily | Homologous Superfamily | |
IPR050200 | Nuclear hormone receptor family NR3 subfamily | Family | |
IPR001723 | Nuclear hormone receptor | Family | |
IPR000536 | Nuclear hormone receptor, ligand-binding domain | Domain | |
IPR035500 | Nuclear hormone receptor-like domain superfamily | Homologous Superfamily | |
IPR033544 | Nuclear receptor subfamily 0 group B member 1/2 | Family |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
Q15466 | :