Annotations: 6PC0

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PRK10854	e6pc0A3	A: alpha complex topology	X: PDEase-like	H: HD-domain/PDEase-like (From Topology)	T: HD-domain/PDEase-like	F: PRK10854	ECOD (1.6)
A	Ppx-GppA_N	e6pc0A2	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Ppx-GppA_N	ECOD (1.6)
A	Ppx-GppA_C	e6pc0A1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Ppx-GppA_C	ECOD (1.6)
B	PRK10854	e6pc0B3	A: alpha complex topology	X: PDEase-like	H: HD-domain/PDEase-like (From Topology)	T: HD-domain/PDEase-like	F: PRK10854	ECOD (1.6)
B	Ppx-GppA_N	e6pc0B2	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Ppx-GppA_N	ECOD (1.6)
B	Ppx-GppA_C	e6pc0B1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Ppx-GppA_C	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B	PF02541	Ppx/GppA phosphatase family (Ppx-GppA)	Ppx/GppA phosphatase family	-	Family
A, B	PF21447	Ppx/GppA phosphatase, domain III (Ppx-GppA_III)	Ppx/GppA phosphatase, domain III	Ppx/GppA phosphatases belong to ASKHA (acetate and sugar kinases, Hsp70, actin) which has an N-terminal (Pfam:PF02541) nucleotide-binding domain (domains I/II), domain III which corresponds to the catalytic phosphohydrolase domain with the common hel ...	Ppx/GppA phosphatases belong to ASKHA (acetate and sugar kinases, Hsp70, actin) which has an N-terminal (Pfam:PF02541) nucleotide-binding domain (domains I/II), domain III which corresponds to the catalytic phosphohydrolase domain with the common helical fold and domain IV [1-3]. This entry represents domain III.	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Guanosine pentaphosphate phosphohydrolase	pyrophosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	-

Chains	Accession	Name	Type
A, B	IPR050273	GppA/Ppx guanosine pentaphosphate hydrolase	Family
A, B	IPR048950	Ppx/GppA phosphatase, C-terminal	Domain
A, B	IPR030673	Pyrophosphatase, GppA/Ppx-type	Family
A, B	IPR043129	ATPase, nucleotide binding domain	Homologous Superfamily
A, B	IPR003695	Ppx/GppA phosphatase, N-terminal	Domain