Annotations: 6CZ6

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UNK_F_TYPE	e6cz6A2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: UNK_F_TYPE	ECOD (1.6)
A	UNK_F_TYPE	e6cz6A1	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: UNK_F_TYPE	ECOD (1.6)
B	UNK_F_TYPE	e6cz6B2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: UNK_F_TYPE	ECOD (1.6)
B	UNK_F_TYPE	e6cz6B1	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: UNK_F_TYPE	ECOD (1.6)
C	UNK_F_TYPE	e6cz6C2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: UNK_F_TYPE	ECOD (1.6)
C	UNK_F_TYPE	e6cz6C1	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: UNK_F_TYPE	ECOD (1.6)
D	UNK_F_TYPE	e6cz6D2	A: a+b three layers	X: Profilin-like	H: sensor domains (From Topology)	T: sensor domains	F: UNK_F_TYPE	ECOD (1.6)
D	UNK_F_TYPE	e6cz6D1	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: UNK_F_TYPE	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF06114	IrrE N-terminal-like domain (Peptidase_M78)	IrrE N-terminal-like domain	-	Family
A, B, C, D	PF09856	Short-chain fatty acyl coenzyme A regulator, C-terminal (ScfRs)	Short-chain fatty acyl coenzyme A regulators	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	HTH-type transcriptional regulator PrpR	DNA binding binding organic cyclic compound binding nucleic acid binding transcription regulator activity DNA-binding transcription factor activity	regulation of cellular process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation primary metabolic process regulation of cellular process RNA metabolic process regulation of primary metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of biosynthetic process regulation of biological process biological regulation primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of gene expression biosynthetic process metabolic process cellular process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription macromolecule metabolic process regulation of metabolic process response to host defenses biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to defenses of other organism response to external stimulus response to biotic stimulus biological process involved in interaction with host biological process involved in symbiotic interaction response to host immune response response to host response to external biotic stimulus response to decreased oxygen levels response to hypoxia response to stress response to oxygen levels response to abiotic stimulus fatty acid metabolic process oxoacid metabolic process short-chain fatty acid metabolic process carboxylic acid metabolic process organic acid metabolic process small molecule metabolic process propionate metabolic process, methylcitrate cycle monocarboxylic acid metabolic process propionate metabolic process lipid metabolic process organic hydroxy compound metabolic process sterol metabolic process steroid metabolic process cholesterol metabolic process alcohol metabolic process secondary alcohol metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR001387	Cro/C1-type helix-turn-helix domain	Domain
A, B, C, D	IPR050807	Bacterial transcriptional regulator/dioxygenase	Family
A, B, C, D	IPR018653	Short-chain fatty acyl coenzyme A regulators, C-terminal	Domain
A, B, C, D	IPR010982	Lambda repressor-like, DNA-binding domain superfamily	Homologous Superfamily
A, B, C, D	IPR026281	HTH-type transcriptional regulator RamB	Family
A, B, C, D	IPR010359	IrrE N-terminal-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.