5BNC

Structure of heme binding protein MSMEG_6519 from Mycobacterium smegmatis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d5bncb_	All beta proteins	Split barrel-like	FMN-binding split barrel	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
A	d5bnca_	All beta proteins	Split barrel-like	FMN-binding split barrel	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2 Family	PNP-oxidase like	8088719	4002129	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	FMN-binding split barrel	8088720	3000856	SCOP2 (2022-06-29)
A	SCOP2B Superfamily	FMN-binding split barrel	8088720	3000856	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Pyrid_oxidase_2	e5bncB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: Pyrid_oxidase_2	ECOD (1.6)
B	DUF2470	e5bncB2	A: a+b two layers	X: a+b domain in heme oxygenase (From Topology)	H: a+b domain in heme oxygenase (From Topology)	T: a+b domain in heme oxygenase	F: DUF2470	ECOD (1.6)
A	Pyrid_oxidase_2	e5bncA2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: FMN-binding split barrel	F: Pyrid_oxidase_2	ECOD (1.6)
A	DUF2470	e5bncA1	A: a+b two layers	X: a+b domain in heme oxygenase (From Topology)	H: a+b domain in heme oxygenase (From Topology)	T: a+b domain in heme oxygenase	F: DUF2470	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.30.110.10	Mainly Beta	Roll	Pnp Oxidase	Chain A	CATH (4.3.0)
B	3.20.180.10	Alpha Beta	Alpha-Beta Barrel	Split barrel-like	PNP-oxidase-like	CATH (4.3.0)
A	2.30.110.10	Mainly Beta	Roll	Pnp Oxidase	Chain A	CATH (4.3.0)
A	3.20.180.10	Alpha Beta	Alpha-Beta Barrel	Split barrel-like	PNP-oxidase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF13883	Pyridoxamine 5'-phosphate oxidase (Pyrid_oxidase_2)	Pyridoxamine 5'-phosphate oxidase	-	Domain
A, B	PF10615	Domain of unknown function (DUF2470) (DUF2470)	Domain of unknown function (DUF2470)	This domain is found in a group of putative heme-iron utilisation proteins, such as HugZ. It can also be found in C-terminal of the glutamyl-tRNA reductase-binding (GluTRBP) protein from Arabidopsis [1]. GluTRBP is involved in the regulation of gluta ...	This domain is found in a group of putative heme-iron utilisation proteins, such as HugZ. It can also be found in C-terminal of the glutamyl-tRNA reductase-binding (GluTRBP) protein from Arabidopsis [1]. GluTRBP is involved in the regulation of glutamyl-tRNA reductase (GluTR) which is important for the synthesis and distribution of 5-aminolevulinate, a precursor in heme and chlorophyll biosynthesis [2]. GluTRBP is necessary for efficient photosynthetic electron transport in chloroplasts [3].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	heme binding protein MSMEG_6519	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR012349	FMN-binding split barrel	Homologous Superfamily
A, B	IPR037119	Haem oxygenase HugZ-like superfamily	Homologous Superfamily
A, B	IPR019595	Domain of unknown function DUF2470	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.