Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042531 3000526 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB TolC docking domain (DN and DC subdomains) 8042533 3000526 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042523 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042528 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042529 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042534 3000769 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB pore domain PN1, PN2, PC1 and PC2 subdomains 8042525 3000503 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyMultidrug efflux transporter AcrB transmembrane domain 8042535 3000769 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AACR_tran_4the4ziwA5 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
AACR_tran_1ste4ziwA3 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
AACR_tran_5the4ziwA6 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
AACR_tran_3rde4ziwA4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
AACR_tran_6the4ziwA7 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
AACR_tran_2nde4ziwA1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
AACR_tran_6th_1e4ziwA2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
BACR_tran_4the4ziwB5 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
BACR_tran_1ste4ziwB2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
BACR_tran_5the4ziwB8 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
BACR_tran_3rde4ziwB1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
BACR_tran_6the4ziwB6 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
BACR_tran_2nde4ziwB3 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
BACR_tran_6th_1e4ziwB4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
CACR_tran_4the4ziwC5 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
CACR_tran_1ste4ziwC6 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
CACR_tran_5the4ziwC2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
CACR_tran_3rde4ziwC1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
CACR_tran_6the4ziwC8 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
CACR_tran_2nde4ziwC4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
CACR_tran_6th_1e4ziwC3 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
DACR_tran_4the4ziwD6 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
DACR_tran_1ste4ziwD1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
DACR_tran_5the4ziwD7 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
DACR_tran_3rde4ziwD8 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
DACR_tran_6the4ziwD4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
DACR_tran_2nde4ziwD5 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
DACR_tran_6th_1e4ziwD2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
EACR_tran_4the4ziwE7 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
EACR_tran_1ste4ziwE6 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
EACR_tran_5the4ziwE3 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
EACR_tran_3rde4ziwE4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
EACR_tran_6the4ziwE1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
EACR_tran_2nde4ziwE2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
EACR_tran_6th_1e4ziwE8 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)
FACR_tran_4the4ziwF8 A: alpha bundlesX: Multidrug efflux transporter AcrB transmembrane domain (From Topology)H: Multidrug efflux transporter AcrB transmembrane domain (From Topology)T: Multidrug efflux transporter AcrB transmembrane domainF: ACR_tran_4thECOD (1.6)
FACR_tran_1ste4ziwF2 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_1stECOD (1.6)
FACR_tran_5the4ziwF4 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_5thECOD (1.6)
FACR_tran_3rde4ziwF7 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_3rdECOD (1.6)
FACR_tran_6the4ziwF5 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB pore domainF: ACR_tran_6thECOD (1.6)
FACR_tran_2nde4ziwF1 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_2ndECOD (1.6)
FACR_tran_6th_1e4ziwF3 A: a+b two layersX: Alpha-beta plaitsH: Ferredoxin domains in multidrug efflux transporterT: Multidrug efflux transporter AcrB TolC docking domainF: ACR_tran_6th_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
A3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
A3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
A3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
A3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
B1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
B3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
B3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
B3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
B3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
C1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
C3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
C3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
C3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
C3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
D1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
D3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
D3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
D3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
D3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
E1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
E3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
E3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
E3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
E3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
F1.20.1640.10 Mainly Alpha Up-down Bundle Multidrug efflux transporter AcrB transmembrane fold Multidrug efflux transporter AcrB transmembrane domainCATH (4.3.0)
F3.30.70.1430 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)
F3.30.70.1320 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domain likeCATH (4.3.0)
F3.30.2090.10 Alpha Beta 2-Layer Sandwich Multidrug efflux transporter AcrB TolC docking domain DN and DC subdomainsCATH (4.3.0)
F3.30.70.1440 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Multidrug efflux transporter AcrB pore domainCATH (4.3.0)

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
A, B, C, D, E
ARO:3000216acrBProtein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
A, B, C, D, E
ARO:0010004resistance-nodulation-cell division (RND) antibiotic efflux pumpfluoroquinolone antibiotic, cephalosporin, glycylcycline, penam, tetracycline antibiotic, rifamycin antibiotic, phenicol antibiotic, disinfecting agents and antisepticsantibiotic effluxCARD (3.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Multidrug efflux pump subunit AcrB

InterPro: Protein Family Classification InterPro Database Homepage

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
MemProtMDAnnotated as membrane protein by MemProtMD