4CQ9
Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) in complex with IDI-6253
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d4cq9b_ | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | FMN-linked oxidoreductases | FMN-linked oxidoreductases | automated matches | (Plasmodium falciparum ) [TaxId: 5833 ], | SCOPe (2.08) |
A | d4cq9a_ | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | FMN-linked oxidoreductases | FMN-linked oxidoreductases | automated matches | (Plasmodium falciparum ) [TaxId: 5833 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | DHO_dh | e4cq9B1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: DHO_dh | ECOD (1.6) |
A | DHO_dh | e4cq9A1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: DHO_dh | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.20.20.70 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | CATH (4.3.0) |
A | 3.20.20.70 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01180 | Dihydroorotate dehydrogenase (DHO_dh) | Dihydroorotate dehydrogenase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR013785 | Aldolase-type TIM barrel | Homologous Superfamily | |
IPR005719 | Dihydroorotate dehydrogenase, class 2 | Family | |
IPR005720 | Dihydroorotate dehydrogenase, catalytic | Domain | |
IPR001295 | Dihydroorotate dehydrogenase, conserved site | Conserved Site | |
IPR050074 | Dihydroorotate dehydrogenase | Family |