Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.1460 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
C3.40.50.1460 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
D3.30.70.1470 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Caspase-likeCATH (4.3.0)
B3.30.70.1470 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits Caspase-likeCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF00656Caspase domain (Peptidase_C14)Caspase domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C
Caspase-7
B, D
Caspase-7
E, F
Acetyl-YVAD-CHO---

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, C
PharosP55210
B, D
PharosP55210

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
E, F
ACE RESIDAA0041 , AA0042 , AA0043 , AA0044 , AA0045 , AA0046 , AA0049 , AA0050 , AA0051 , AA0052 , AA0053 , AA0054 , AA0354

PSI-MOD :  N-acetyl-L-alanine MOD:00050 , N-acetyl-L-aspartic acid MOD:00051 , N-acetyl-L-cysteine MOD:00052 , N-acetyl-S-archeol-cysteine MOD:00897 , N-acetyl-L-glutamic acid MOD:00053 , N-acetyl-L-glutamine MOD:00054 , N-acetylglycine MOD:00055 , N-acetyl-L-methionine MOD:00058 , N-acetyl-L-proline MOD:00059 , N-acetyl-L-serine MOD:00060 , N,O-diacetylated L-serine MOD:00648 , N-acetyl-L-threonine MOD:00061 , N-acetyl-L-tyrosine MOD:00062 , N-acetyl-L-valine MOD:00063 , N2-acetyl-L-arginine MOD:00359