2WA9

Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS - Trp peptide structure

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ClpS-like	8032304	3000936	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	ClpS	e2wa9A1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
B	ClpS	e2wa9B1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
G	ClpS	e2wa9G1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
C	ClpS	e2wa9C1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
D	ClpS	e2wa9D1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
E	ClpS	e2wa9E1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)
F	ClpS	e2wa9F1	A: a+b two layers	X: ClpS-like	H: ClpS-related (From Topology)	T: ClpS-related	F: ClpS	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
B	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
G	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
C	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
D	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
E	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
F	3.30.1390.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G	PF02617	ATP-dependent Clp protease adaptor protein ClpS (ClpS)	ATP-dependent Clp protease adaptor protein ClpS	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G	ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS	protein binding binding protein-folding chaperone binding molecular function inhibitor activity molecular function regulator activity	catabolic process metabolic process cellular process primary metabolic process protein catabolic process protein metabolic process macromolecule metabolic process macromolecule catabolic process proteolysis response to stimulus response to stress response to heat response to abiotic stimulus response to temperature stimulus	-
H, I, J, K, L H, I, J, K, L, M, N	TRP PEPTIDE	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G	IPR003769	Adaptor protein ClpS, core	Domain
A, B, C, D, E A, B, C, D, E, F, G	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G	IPR022935	ATP-dependent Clp protease adaptor protein ClpS	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.