2NSF | pdb_00002nsf

Crystal structure of the mycothiol-dependent maleylpyruvate isomerase

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2nsfa1	All alpha proteins	DinB/YfiT-like putative metalloenzymes	DinB/YfiT-like putative metalloenzymes	Maleylpyruvate isomerase-like	Micothiol-dependent maleylpyruvate isomerase	(Corynebacterium glutamicum ) [TaxId: 1718 ],	SCOPe (2.08)
A	d2nsfa2	Alpha and beta proteins (a+b)	SCP-like	SCP-like	Micothiol-dependent maleylpyruvate isomerase C-terminal domain-like	Micothiol-dependent maleylpyruvate isomerase	(Corynebacterium glutamicum ) [TaxId: 1718 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Maleylpyruvate isomerase-like	8022470	4001390	SCOP2 (2022-06-29)
A	SCOP2 Family	Micothiol-dependent maleylpyruvate isomerase C-terminal domain-like	8022471	4002268	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	DinB/YfiT-like putative metalloenzymes	8034850	3001308	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	SCP2-like	8034851	3000148	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MDMPI_N	e2nsfA1	A: alpha bundles	X: YfiT-like putative metal-dependent hydrolases (From Topology)	H: YfiT-like putative metal-dependent hydrolases (From Topology)	T: YfiT-like putative metal-dependent hydrolases	F: MDMPI_N	ECOD (1.6)
A	PRK09583	e2nsfA2	A: a+b two layers	X: Sterol carrier protein-like	H: Sterol carrier protein, SCP-related (From Topology)	T: Sterol carrier protein, SCP-related	F: PRK09583	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.120.450	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	dinb family like domain	CATH (4.3.0)
A	3.30.1050.20	Alpha Beta	2-Layer Sandwich	Nonspecific Lipid-transfer Protein	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07398	MDMPI C-terminal domain (MDMPI_C)	MDMPI C-terminal domain	This domain is found at the C-terminus of the mycothiol maleylpyruvate isomerase enzyme (MDMPI). The structure of this protein has been solved [1]. This domain appears weakly similar to Pfam:PF08608.	Domain
A	PF11716	Mycothiol maleylpyruvate isomerase N-terminal domain (MDMPI_N)	Mycothiol maleylpyruvate isomerase N-terminal domain		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Hypothetical protein Cgl3021	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036527	SCP2 sterol-binding domain superfamily	Homologous Superfamily
A	IPR017517	Maleylpyruvate isomerase, mycothiol-dependent enzyme	Family
A	IPR010872	MDMPI C-terminal	Domain
A	IPR024344	Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain	Domain
A	IPR034660	DinB/YfiT-like putative metalloenzymes	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.