Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1hkxa_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Bd1hkxb_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Cd1hkxc_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Dd1hkxd_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Ed1hkxe_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Fd1hkxf_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Gd1hkxg_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Hd1hkxh_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Id1hkxi_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Jd1hkxj_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Kd1hkxk_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Ld1hkxl_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Md1hkxm_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Nd1hkxn_ Alpha and beta proteins (a+b) Cystatin-like NTF2-like Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A MOUSE (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyAssociation domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A 8032145 4000593 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyNTF2-like 8044523 3000472 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
LSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
MSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)
NSCOP2B SuperfamilyNTF2-like 8044523 3000472 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADUF4440e1hkxA1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
BDUF4440e1hkxB1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
CDUF4440e1hkxC1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
DDUF4440e1hkxD1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
EDUF4440e1hkxE1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
FDUF4440e1hkxF1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
GDUF4440e1hkxG1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
HDUF4440e1hkxH1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
IDUF4440e1hkxI1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
JDUF4440e1hkxJ1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
KDUF4440e1hkxK1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
LDUF4440e1hkxL1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
MDUF4440e1hkxM1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)
NDUF4440e1hkxN1 A: a+b two layersX: Cystatin-likeH: NTF2-like (From Topology)T: NTF2-likeF: DUF4440ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF08332Calcium/calmodulin dependent protein kinase II association domain (CaMKII_AD)Calcium/calmodulin dependent protein kinase II association domainThis domain is found at the C-terminus of the Calcium/calmodulin dependent protein kinases II (CaMKII). These proteins also have a Ser/Thr protein kinase domain (Pfam:PF00069) at their N-terminus [1]. The function of the CaMKII association domain i ...This domain is found at the C-terminus of the Calcium/calmodulin dependent protein kinases II (CaMKII). These proteins also have a Ser/Thr protein kinase domain (Pfam:PF00069) at their N-terminus [1]. The function of the CaMKII association domain is the assembly of the single proteins into large (8 to 14 subunits) multimers [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR032710NTF2-like domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR017441Protein kinase, ATP binding siteBinding Site
A, B, C, D, E
IPR013543Calcium/calmodulin-dependent protein kinase II, association-domainDomain
A, B, C, D, E
IPR000719Protein kinase domainDomain
A, B, C, D, E
IPR011009Protein kinase-like domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR008271Serine/threonine-protein kinase, active siteActive Site