Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Bd1jkjb1 Alpha and beta proteins (a/b) Flavodoxin-like Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains Succinyl-CoA synthetase, beta-chain, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1jkjb2 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase, beta-chain, N-terminal domain Succinyl-CoA synthetase, beta-chain, N-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth E]d1jkje1 Alpha and beta proteins (a/b) Flavodoxin-like Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains Succinyl-CoA synthetase, beta-chain, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
D [auth E]d1jkje2 Alpha and beta proteins (a+b) ATP-grasp Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase, beta-chain, N-terminal domain Succinyl-CoA synthetase, beta-chain, N-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1jkja1 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains CoA-binding domain Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1jkja2 Alpha and beta proteins (a/b) Flavodoxin-like Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains Succinyl-CoA synthetase, alpha-chain, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d1jkjd1 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains CoA-binding domain Succinyl-CoA synthetase, alpha-chain, N-terminal (CoA-binding) domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
C [auth D]d1jkjd2 Alpha and beta proteins (a/b) Flavodoxin-like Succinyl-CoA synthetase domains Succinyl-CoA synthetase domains Succinyl-CoA synthetase, alpha-chain, C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilySuccinyl-CoA synthetase domain-like 8017596 3000003 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8002631 3000094 SCOP2B (2022-06-29)
D [auth E]SCOP2B SuperfamilyGlutathione synthetase ATP-binding domain-like 8002631 3000094 SCOP2B (2022-06-29)
D [auth E]SCOP2B SuperfamilySuccinyl-CoA synthetase domain-like 8017596 3000003 SCOP2B (2022-06-29)
ASCOP2B SuperfamilySuccinyl-CoA synthetase domain-like 8001535 3000003 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyCoA-binding Rossmann-fold domain 8017583 3000049 SCOP2B (2022-06-29)
C [auth D]SCOP2B SuperfamilySuccinyl-CoA synthetase domain-like 8001535 3000003 SCOP2B (2022-06-29)
C [auth D]SCOP2B SuperfamilyCoA-binding Rossmann-fold domain 8017583 3000049 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BATP-grasp_2e1jkjB1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-grasp_2ECOD (1.6)
BCitrate_binde1jkjB2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Citrate_bindECOD (1.6)
D [auth E]ATP-grasp_2e1jkjE1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: ATP-grasp_2ECOD (1.6)
D [auth E]Citrate_binde1jkjE2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Citrate_bindECOD (1.6)
ACoA_bindinge1jkjA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: CoA_bindingECOD (1.6)
ASucc_CoA_lige1jkjA2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Succ_CoA_ligECOD (1.6)
C [auth D]CoA_bindinge1jkjD1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: CoA_bindingECOD (1.6)
C [auth D]Succ_CoA_lige1jkjD2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Succinyl-CoA synthetase domains (From Topology)T: Succinyl-CoA synthetase domainsF: Succ_CoA_ligECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
B,
D [auth E]
PF08442ATP-grasp domain (ATP-grasp_2)ATP-grasp domain- Domain
B,
D [auth E]
PF00549CoA-ligase (Ligase_CoA)CoA-ligaseThis family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilise ATP others use GTP.Domain
A,
C [auth D]
PF00549CoA-ligase (Ligase_CoA)CoA-ligaseThis family includes the CoA ligases Succinyl-CoA synthetase alpha and beta chains, malate CoA ligase and ATP-citrate lyase. Some members of the family utilise ATP others use GTP.Domain
A,
C [auth D]
PF02629CoA binding domain (CoA_binding)CoA binding domainThis domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
B,
D [auth E]
succinyl-CoA synthetase beta subunit
A,
C [auth D]
succinyl-CoA synthetase alpha subunit