Annotations: 1F8X

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1f8xa_	Alpha and beta proteins (a/b)	Flavodoxin-like	N-(deoxy)ribosyltransferase-like	N-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase	(Lactobacillus leichmannii ) [TaxId: 28039 ],	SCOPe (2.08)
B	d1f8xb_	Alpha and beta proteins (a/b)	Flavodoxin-like	N-(deoxy)ribosyltransferase-like	N-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase	(Lactobacillus leichmannii ) [TaxId: 28039 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	N-(deoxy)ribosyltransferase-like	8044137	3001392	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	N-(deoxy)ribosyltransferase-like	8044137	3001392	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Nuc_deoxyrib_tr	e1f8xA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: N-deoxyribosyltransferase (From Topology)	T: N-deoxyribosyltransferase	F: Nuc_deoxyrib_tr	ECOD (1.6)
B	Nuc_deoxyrib_tr	e1f8xB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: N-deoxyribosyltransferase (From Topology)	T: N-deoxyribosyltransferase	F: Nuc_deoxyrib_tr	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.450	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
B	3.40.50.450	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF05014	Nucleoside 2-deoxyribosyltransferase (Nuc_deoxyrib_tr)	Nucleoside 2-deoxyribosyltransferase	Nucleoside 2-deoxyribosyltransferase EC:2.4.2.6 catalyses the cleavage of the glycosidic bonds of 2`-deoxyribonucleosides [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE	nucleoside deoxyribosyltransferase activity pentosyltransferase activity glycosyltransferase activity transferase activity catalytic activity	nucleoside phosphate metabolic process nucleotide biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleotide metabolic process nucleotide salvage nucleobase-containing compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleobase-containing small molecule metabolic process nucleoside phosphate biosynthetic process phosphate-containing compound metabolic process metabolic process nucleoside phosphate metabolic process nucleotide biosynthetic process primary metabolic process nucleobase-containing compound biosynthetic process nucleotide metabolic process nucleotide salvage nucleobase-containing compound metabolic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleobase-containing small molecule metabolic process nucleoside phosphate biosynthetic process phosphate-containing compound metabolic process metabolic process cellular process small molecule metabolic process cellular metabolic compound salvage phosphorus metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR007710	Nucleoside 2-deoxyribosyltransferase	Family

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	nucleoside deoxyribosyltransferase M-CSA #554	Nucleoside 2'-deoxyribosyltransferase catalyses cleavage of the 2'-deoxyribosyl-nucleoside glycosidic bond through the formation of a covalent deoxyribosyl-enzyme intermediate. The enzyme is found in various Lactobacilli species where it participates in nucleoside recycling. There is considerable interest for nucleoside 2'-deoxyribosyltransferase to be used as an industrial biocatalyst in creating natural and non-natural nucleosides.	Defined by 4 residues: TYR:A-7ASP:A-72ASP:A-92GLU:A-98 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 2.4.2.6 (PDB Primary Data) Search M-CSA Motif + EC 2.4.2.6

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