8UOJ | pdb_00008uoj

Crystal structure of human NUAK1-MARK3 kinase domain chimera bound with azepane (R)-#50 small molecule inhibitor

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​G​​A​​M​​G​​S​​D​​E​​Q​​P​​H​53   ​I​​G​​N​​Y​​R​​L​​L​​K​​T​​L​63   ​G​​K​​G​​N​​F​​A​​K​​V​​K​​R​73   ​A​​R​​H​​I​​L​​T​​G​​R​​E​​V​83   ​A​​I​​K​​I​​I​​D​​K​​T​​Q​​L​93   ​N​​P​​T​​S​​L​​Q​​K​​L​​F​​R​103  ​E​​V​​R​​I​​M​​K​​I​​L​​N​​H​113  ​P​​N​​I​​I​​K​​L​​F​​E​​V​​I​123  ​E​​T​​E​​K​​T​​L​​Y​​L​​I​​M​133  ​E​​Y​​A​​S​​K​​G​​E​​V​​Y​​D​143  ​Y​​L​​V​​E​​H​​G​​R​​M​​K​​E​153  ​K​​E​​A​​R​​S​​K​​F​​R​​Q​​I​163  ​V​​S​​A​​V​​Q​​Y​​C​​H​​Q​​K​173  ​R​​I​​V​​H​​R​​D​​L​​K​​A​​E​183  ​N​​L​​L​​L​​D​​A​​D​​M​​N​​I​193  ​K​​I​​A​​D​​F​​G​​F​​S​​N​​E​203  ​F​​T​​V​​G​​G​​K​​L​​D​​T​​F​213  ​CME​​G​​S​​P​​P​​Y​​A​​A​​P​​E​223  ​L​​F​​Q​​G​​K​​K​​Y​​D​​G​​P​233  ​E​​V​​D​​V​​W​​S​​L​​G​​V​​I​243  ​L​​Y​​T​​L​​V​​S​​G​​S​​L​​P​253  ​F​​D​​G​​Q​​N​​L​​K​​E​​L​​R​263  ​E​​R​​V​​L​​R​​G​​K​​Y​​R​​I​273  ​P​​F​​Y​​M​​S​​T​​D​​C​​E​​N​283  ​L​​L​​K​​R​​F​​L​​V​​L​​N​​P​293  ​I​​K​​R​​G​​T​​L​​E​​Q​​I​​M​303  ​K​​D​​R​​W​​I​​N​​A​​G​​H​​E​313  ​E​​D​​E​​L​​K​​P​​F​​V​​E​​P​323  ​E​​L​​D​​I​​S​​D​​Q​​K​​R​​I​333  ​D​​I​​M​​V​​G​​M​​G​​Y​​S​​Q​343  ​E​​E​​I​​Q​​E​​S​​L​​S​​K​​M​353  ​K​​Y​​D​​E​​I​​T​​A​​T​​Y​​L​363  ​L​​L​​G​​R​​K​​S​​S​​E​
Type
Asm Id
Dynamic Bonds

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