3D View: 3N8W

Crystal Structure of R120Q/Native Cyclooxygenase-1 Heterodimer mutant in complex with Flurbiprofen

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Sequence of
32   ​P​​V​​N​​P​​C​​C​​Y​​Y​​P​​C​42   ​Q​​H​​Q​​G​​I​​C​​V​​R​​F​​G​52   ​L​​D​​R​​Y​​Q​​C​​D​​C​​T​​R​62   ​T​​G​​Y​​S​​G​​P​​N​​C​​T​​I​72   ​P​​E​​I​​W​​T​​W​​L​​R​​T​​T​82   ​L​​R​​P​​S​​P​​S​​F​​I​​H​​F​92   ​L​​L​​T​​H​​G​​R​​W​​L​​W​​D​102  ​F​​V​​N​​A​​T​​F​​I​​R​​D​​T​112  ​L​​M​​R​​L​​V​​L​​T​​V​​R​​S​122  ​N​​L​​I​​P​​S​​P​​P​​T​​Y​​N​132  ​I​​A​​H​​D​​Y​​I​​S​​W​​E​​S​142  ​F​​S​​N​​V​​S​​Y​​Y​​T​​R​​I​152  ​L​​P​​S​​V​​P​​R​​D​​C​​P​​T​162  ​P​​M​​G​​T​​K​​G​​K​​K​​Q​​L​172  ​P​​D​​A​​E​​F​​L​​S​​R​​R​​F​182  ​L​​L​​R​​R​​K​​F​​I​​P​​D​​P​192  ​Q​​G​​T​​N​​L​​M​​F​​A​​F​​F​202  ​A​​Q​​H​​F​​T​​H​​Q​​F​​F​​K​212  ​T​​S​​G​​K​​M​​G​​P​​G​​F​​T​222  ​K​​A​​L​​G​​H​​G​​V​​D​​L​​G​232  ​H​​I​​Y​​G​​D​​N​​L​​E​​R​​Q​242  ​Y​​Q​​L​​R​​L​​F​​K​​D​​G​​K​252  ​L​​K​​Y​​Q​​M​​L​​N​​G​​E​​V​262  ​Y​​P​​P​​S​​V​​E​​E​​A​​P​​V​272  ​L​​M​​H​​Y​​P​​R​​G​​I​​P​​P​282  ​Q​​S​​Q​​M​​A​​V​​G​​Q​​E​​V​292  ​F​​G​​L​​L​​P​​G​​L​​M​​L​​Y​302  ​A​​T​​I​​W​​L​​R​​E​​H​​N​​R​312  ​V​​C​​D​​L​​L​​K​​A​​E​​H​​P​322  ​T​​W​​G​​D​​E​​Q​​L​​F​​Q​​T​332  ​A​​R​​L​​I​​L​​I​​G​​E​​T​​I​342  ​K​​I​​V​​I​​E​​E​​Y​​V​​Q​​Q​352  ​L​​S​​G​​Y​​F​​L​​Q​​L​​K​​F​362  ​D​​P​​E​​L​​L​​F​​G​​A​​Q​​F​372  ​Q​​Y​​R​​N​​R​​I​​A​​M​​E​​F​382  ​N​​Q​​L​​Y​​H​​W​​H​​P​​L​​M​392  ​P​​D​​S​​F​​R​​V​​G​​P​​Q​​D​402  ​Y​​S​​Y​​E​​Q​​F​​L​​F​​N​​T​412  ​S​​M​​L​​V​​D​​Y​​G​​V​​E​​A​422  ​L​​V​​D​​A​​F​​S​​R​​Q​​P​​A​432  ​G​​R​​I​​G​​G​​G​​R​​N​​I​​D​442  ​H​​H​​I​​L​​H​​V​​A​​V​​D​​V​452  ​I​​K​​E​​S​​R​​V​​L​​R​​L​​Q​462  ​P​​F​​N​​E​​Y​​R​​K​​R​​F​​G​472  ​M​​K​​P​​Y​​T​​S​​F​​Q​​E​​L​482  ​T​​G​​E​​K​​E​​M​​A​​A​​E​​L​492  ​E​​E​​L​​Y​​G​​D​​I​​D​​A​​L​502  ​E​​F​​Y​​P​​G​​L​​L​​L​​E​​K​512  ​C​​H​​P​​N​​S​​I​​F​​G​​E​​S​522  ​M​​I​​E​​M​​G​​A​​P​​F​​S​​L​532  ​K​​G​​L​​L​​G​​N​​P​​I​​C​​S​542  ​P​​E​​Y​​W​​K​​A​​S​​T​​F​​G​552  ​G​​E​​V​​G​​F​​N​​L​​V​​K​​T​562  ​A​​T​​L​​K​​K​​L​​V​​C​​L​​N​572  ​T​​K​​T​​C​​P​​Y​​V​​S​​F​​H​582  ​V​​P​​D​
Type
Asm Id
Dynamic Bonds

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