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235,183 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 3.2.2.27

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Search Summary

This query matches 161 Structures.

Refinements

Structure Determination Methodology

experimental (161)

Scientific Name of Source Organism

	Mycobacterium tuberculosis H37Rv (32)
	Homo sapiens (25)
	Monkeypox virus (20)
	Mycolicibacterium smegmatis MC2 155 (15)
	Bacillus phage PBS2 (9)
	Vaccinia virus Copenhagen (9)
	Staphylococcus aureus (7)
	DNA molecule (6)
	Escherichia coli B (6)
	synthetic construct (6)

More...

Taxonomy

	Bacteria (80)
	Varidnaviria (41)
	Eukaryota (28)
	Duplodnaviria (25)
	other sequences (6)
	unclassified sequences (6)
	Archaea (3)
	Riboviria (2)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (138)
	ELECTRON MICROSCOPY (22)
	SOLUTION NMR (1)

Polymer Entity Type

	Protein (161)
	DNA (31)

Refinement Resolution (Å)

	0.5 - 1.0 (1)
	1.0 - 1.5 (24)
	1.5 - 2.0 (53)
	2.0 - 2.5 (37)
	2.5 - 3.0 (27)
	3.0 - 3.5 (15)
	3.5 - 4.0 (3)

Release Date

	1995 - 1999 (17)
	2000 - 2004 (13)
	2005 - 2009 (16)
	2010 - 2014 (18)
	2015 - 2019 (38)
	2020 - 2024 (52)
	2025 - 2029 (7)

Enzyme Classification Name

	Hydrolases (161)
	Transferases (23)

Symmetry Type

	Asymmetric (149)
	Cyclic (16)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (73)
	Artifacts (24)
	Alpha and beta proteins (a+b) (10)
	All alpha proteins (1)

AllSelected

1 to 25 of 161 Structures

Page 1 of 7

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1AKZ \| pdb_00001akz	Download File View File

HUMAN URACIL-DNA GLYCOSYLASE

Tainer, J.A., Mol, C.D.

(1998) EMBO J 17: 5214-5226

Released	1997-08-20
Method	X-RAY DIFFRACTION 1.57 Å
Organisms	Homo sapiens
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)

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1DPU \| pdb_00001dpu	Download File View File

SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN RPA32 COMPLEXED WITH UNG2(73-88)

Mer, G., Edwards, A.M., Chazin, W.J.

(2000) Cell 103: 449-456

Released	2000-11-10
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	REPLICATION PROTEIN A (RPA32) C-TERMINAL DOMAIN (protein) URACIL DNA GLYCOSYLASE (UNG2) (protein)

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1EMH \| pdb_00001emh	Download File View File

CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE BOUND TO UNCLEAVED SUBSTRATE-CONTAINING DNA

Parikh, S.S., Slupphaug, G., Krokan, H.E., Blackburn, G.M., Tainer, J.A.

(2000) Proc Natl Acad Sci U S A 97: 5083-5088

Released	2000-05-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) DNA (5'-D(APAPAPGPAPTPAPAPCPA)-3') (nucleic acid) DNA (5'-D(TPGPTP(P2U)PAPTPCPTP*T)-3') (nucleic acid)

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1EMJ \| pdb_00001emj	Download File View File

URACIL-DNA GLYCOSYLASE BOUND TO DNA CONTAINING A 4'-THIO-2'DEOXYURIDINE ANALOG PRODUCT

Parikh, S.S., Walcher, G., Jones, G.D., Slupphaug, G., Krokan, H.E., Blackburn, G.M., Tainer, J.A.

(2000) Proc Natl Acad Sci U S A 97: 5083-5088

Released	2000-05-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) DNA (5'-D(APAPAPGPAPTPAPAPCPA)-3') (nucleic acid) DNA (5'-D(TPGPTP(ASU)PAPTPCPTP*T)-3') (nucleic acid)
Unique Ligands	URA

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1EUG \| pdb_00001eug	Download File View File

CRYSTAL STRUCTURE OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE AND ITS COMPLEXES WITH URACIL AND GLYCEROL: STRUCTURE AND GLYCOSYLASE MECHANISM REVISITED

Xiao, G., Tordova, M., Jagadeesh, J., Drohat, A.C., Stivers, J.T., Gilliland, G.L.

(1999) Proteins 35: 13-24

Released	1999-10-12
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Escherichia coli B
Macromolecule	PROTEIN (GLYCOSYLASE) (protein)

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1EUI \| pdb_00001eui	Download File View File

ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN

Ravishankar, R., Sagar, M.B., Roy, S., Purnapatre, K., Handa, P., Varshney, U., Vijayan, M.

(1998) Nucleic Acids Res 26: 4880-4887

Released	1999-06-22
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Bacillus phage PBS2 Escherichia coli
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN (protein)

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1FLZ \| pdb_00001flz	Download File View File

URACIL DNA GLYCOSYLASE WITH UAAP

Werner, R.M., Jiang, Y.L., Gordley, R.G., Jagadeesh, G.J., Ladner, J.E., Xiao, G., Tordova, M., Gilliland, G.L., Stivers, J.T.

(2000) Biochemistry 39: 12585-12594

Released	2001-01-17
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli B
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)
Unique Ligands	URA

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1L9G \| pdb_00001l9g	Download File View File

CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA

Rajashankar, K.R., Dodatko, T., Thirumuruhan, R.A., Sandigursky, M., Bresnik, A., Chance, M.R., Franklin, W.A., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

To be published

Released	2003-05-27
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermotoga maritima
Macromolecule	Conserved hypothetical protein (protein)
Unique Ligands	SF4, SO4

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1LAU \| pdb_00001lau	Download File View File

URACIL-DNA GLYCOSYLASE

Pearl, L.H., Savva, R.

(1995) Nature 373: 487-493

Released	1996-06-10
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Human alphaherpesvirus 1
Macromolecule	PROTEIN (URACIL-DNA GLYCOSYLASE (E.C.3.2.2.-)) (protein) DNA (5'-D(TPTP*T)-3') (nucleic acid)

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1LQG \| pdb_00001lqg	Download File View File

ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN

Saikrishnan, K., Sagar, M.B., Ravishankar, R., Roy, S., Purnapatre, K., Handa, P., Varshney, U., Vijayan, M.

(2002) Acta Crystallogr D Biol Crystallogr 58: 1269-1276

Released	2002-11-10
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Bacillus phage PBS2 Escherichia coli
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) URACIL-DNA GLYCOSYLASE INHIBITOR (protein)

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1LQJ \| pdb_00001lqj	Download File View File

ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE

Saikrishnan, K., Sagar, M.B., Ravishankar, R., Roy, S., Purnapatre, K., Varshney, U., Vijayan, M.

(2002) Acta Crystallogr D Biol Crystallogr 58: 1269-1276

Released	2002-11-10
Method	X-RAY DIFFRACTION 3.35 Å
Organisms	Escherichia coli
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)

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1LQM \| pdb_00001lqm	Download File View File

ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN

Saikrishnan, K., Sagar, M.B., Ravishankar, R., Roy, S., Purnapatre, K., Varshney, U., Vijayan, M.

(2002) Acta Crystallogr D Biol Crystallogr 58: 1269-1276

Released	2002-11-10
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Bacillus phage PBS2 Escherichia coli
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) URACIL-DNA GLYCOSYLASE INHIBITOR (protein)

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1OKB \| pdb_00001okb	Download File View File

crystal structure of Uracil-DNA glycosylase from Atlantic cod (Gadus morhua)

Leiros, I., Moe, E., Lanes, O., Smalas, A.O., Willassen, N.P.

(2003) Acta Crystallogr D Biol Crystallogr 59: 1357

Released	2004-04-05
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Gadus morhua
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)
Unique Ligands	CL, GOL

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1Q3F \| pdb_00001q3f	Download File View File

Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-containing DNA

Bianchet, M.A., Seiple, L.A., Jiang, Y.L., Ichikawa, Y., Amzel, L.M., Stivers, J.T.

(2003) Biochemistry 42: 12455-12460

Released	2004-03-23
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Uracil-DNA glycosylase (protein) 5'-D(APAPAPGPAPTPAPAPCPA)-3' (nucleic acid) 5'-D(TPGPTP(NRI)PAPTPCPTP*T)-3' (nucleic acid)
Unique Ligands	PO4, URA

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1SSP \| pdb_00001ssp	Download File View File

WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA

Parikh, S.S., Mol, C.D., Slupphaug, G., Bharati, S., Krokan, H.E., Tainer, J.A.

(1998) EMBO J 17: 5214-5226

Released	1999-05-06
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) 5'-D(APAPAPGPAPTPAPAPCPAPG)-3' (nucleic acid) 5'-D(CPTPGPTP(D1P)PAPTPCPTP*T)-3' (nucleic acid)
Unique Ligands	URA

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1UDG \| pdb_00001udg	Download File View File

THE STRUCTURAL BASIS OF SPECIFIC BASE EXCISION REPAIR BY URACIL-DNA GLYCOSYLASE

Pearl, L.H., Savva, R.

(1995) Nature 373: 487-493

Released	1996-01-29
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Human alphaherpesvirus 1 strain 17
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)
Unique Ligands	SO4

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1UDH \| pdb_00001udh	Download File View File

THE STRUCTURAL BASIS OF SPECIFIC BASE EXCISION REPAIR BY URACIL-DNA GLYCOSYLASE

Pearl, L.H., Savva, R.

(1995) Nature 373: 487-493

Released	1996-03-08
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Human alphaherpesvirus 1 strain 17
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)
Unique Ligands	SO4, URA

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1UDI \| pdb_00001udi	Download File View File

NUCLEOTIDE MIMICRY IN THE CRYSTAL STRUCTURE OF THE URACIL-DNA GLYCOSYLASE-URACIL GLYCOSYLASE INHIBITOR PROTEIN COMPLEX

Pearl, L.H., Savva, R.

(1995) Nat Struct Biol 2: 752-757

Released	1996-03-08
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Human alphaherpesvirus 1 strain 17 Takahashivirus PBS1
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN (protein)

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1UGH \| pdb_00001ugh	Download File View File

CRYSTAL STRUCTURE OF HUMAN URACIL-DNA GLYCOSYLASE IN COMPLEX WITH A PROTEIN INHIBITOR: PROTEIN MIMICRY OF DNA

Mol, C.D., Arvai, A.S., Sanderson, R.J., Slupphaug, G., Kavli, B., Krokan, H.E., Mosbaugh, D.W., Tainer, J.A.

(1995) Cell 82: 701-708

Released	1999-02-16
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Bacillus phage PBS2 Homo sapiens
Macromolecule	PROTEIN (URACIL-DNA GLYCOSYLASE INHIBITOR) (protein) PROTEIN (URACIL-DNA GLYCOSYLASE) (protein)

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1UI0 \| pdb_00001ui0	Download File View File

Crystal Structure Of Uracil-DNA Glycosylase From Thermus Thermophilus HB8

Hoseki, J., Okamoto, A., Masui, R., Shibata, T., Inoue, Y., Yokoyama, S., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2003) J Mol Biology 333: 515-526

Released	2003-10-14
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Thermus thermophilus
Macromolecule	Uracil-DNA Glycosylase (protein)
Unique Ligands	SF4, SO4, URA

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1UI1 \| pdb_00001ui1	Download File View File

Crystal Structure Of Uracil-DNA Glycosylase From Thermus Thermophilus HB8

Hoseki, J., Okamoto, A., Masui, R., Shibata, T., Inoue, Y., Yokoyama, S., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2003) J Mol Biology 333: 515-526

Released	2003-10-14
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Thermus thermophilus
Macromolecule	Uracil-DNA Glycosylase (protein)
Unique Ligands	SF4

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1UUG \| pdb_00001uug	Download File View File

ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE:INHIBITOR COMPLEX WITH WILD-TYPE UDG AND WILD-TYPE UGI

Mol, C.D., Arvai, A.S., Putnam, C.D., Tainer, J.A.

(1999) J Mol Biology 287: 331-346

Released	1999-03-25
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Bacillus phage PBS2 Escherichia coli K-12
Macromolecule	URACIL-DNA GLYCOSYLASE (protein) URACIL-DNA GLYCOSYLASE INHIBITOR (protein)

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1VK2 \| pdb_00001vk2	Download File View File

Crystal structure of Uracil-DNA glycosylase (TM0511) from Thermotoga maritima at 1.90 A resolution

Joint Center for Structural Genomics (JCSG)

To be published

Released	2004-05-04
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Thermotoga maritima
Macromolecule	Uracil-DNA glycosylase TM0511 (protein)
Unique Ligands	SF4, UNL

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1YUO \| pdb_00001yuo	Download File View File

Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA N-glycosylase (UNG)from atlantic cod (Gadus morhua)

Moe, E., Leiros, I., Riise, E.K., Olufsen, M., Lanes, O., Smalas, A.O., Willassen, N.P.

(2004) J Mol Biology 343: 1221-1230

Released	2005-03-01
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	Uracil-DNA glycosylase (protein)

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2BOO \| pdb_00002boo	Download File View File

The crystal structure of Uracil-DNA N-Glycosylase (UNG) from Deinococcus radiodurans.

Leiros, I., Moe, E., Smalas, A.O., McSweeney, S.

(2005) Acta Crystallogr D Biol Crystallogr 61: 1049

Released	2005-07-27
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539
Macromolecule	URACIL-DNA GLYCOSYLASE (protein)
Unique Ligands	NO3

1 to 25 of 161 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1AKZ | pdb_00001akz

1DPU | pdb_00001dpu

1EMH | pdb_00001emh

1EMJ | pdb_00001emj

1EUG | pdb_00001eug

1EUI | pdb_00001eui

1FLZ | pdb_00001flz

1L9G | pdb_00001l9g

1LAU | pdb_00001lau

1LQG | pdb_00001lqg

1LQJ | pdb_00001lqj

1LQM | pdb_00001lqm

1OKB | pdb_00001okb

1Q3F | pdb_00001q3f

1SSP | pdb_00001ssp

1UDG | pdb_00001udg

1UDH | pdb_00001udh

1UDI | pdb_00001udi

1UGH | pdb_00001ugh

1UI0 | pdb_00001ui0

1UI1 | pdb_00001ui1

1UUG | pdb_00001uug

1VK2 | pdb_00001vk2

1YUO | pdb_00001yuo

2BOO | pdb_00002boo