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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 2.7.7.7

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Search Summary

This query matches 2,472 Structures.

Refinements

Structure Determination Methodology

experimental (2,472)

Scientific Name of Source Organism

	Homo sapiens (1,116)
	synthetic construct (748)
	Human immunodeficiency virus type 1 BH10 (149)
	Human immunodeficiency virus 1 (128)
	Escherichia phage RB69 (121)
	Geobacillus stearothermophilus (102)
	Escherichia coli (93)
	Saccharolobus solfataricus P2 (92)
	Thermus aquaticus (86)
	Escherichia coli K-12 (76)

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Taxonomy

	Eukaryota (1,267)
	other sequences (754)
	Bacteria (453)
	Riboviria (355)
	Archaea (228)
	Duplodnaviria (186)
	Varidnaviria (55)
	unclassified sequences (34)
	Eukaryota (eukaryotes) (3)
	Adnaviria (1)

More...

Experimental Method

	X-RAY DIFFRACTION (2,200)
	ELECTRON MICROSCOPY (231)
	SOLUTION NMR (41)
	NEUTRON DIFFRACTION (1)

Polymer Entity Type

	Protein (2,472)
	DNA (1,848)
	NA-hybrid (61)
	RNA (40)

Refinement Resolution (Å)

	1.0 - 1.5 (33)
	1.5 - 2.0 (706)
	2.0 - 2.5 (748)
	2.5 - 3.0 (557)
	3.0 - 3.5 (243)
	3.5 - 4.0 (71)
	4.0 - 4.5 (28)
	> 4.5 (46)

Release Date

	1985 - 1989 (1)
	1990 - 1994 (9)
	1995 - 1999 (137)
	2000 - 2004 (105)
	2005 - 2009 (222)
	2010 - 2014 (695)
	2015 - 2019 (610)
	2020 - 2024 (671)
	2025 - 2029 (22)

Enzyme Classification Name

	Transferases (2,472)
	Hydrolases (632)
	Lyases (569)
	Isomerases (5)
	Ligases (1)

Symmetry Type

	Asymmetric (2,274)
	Cyclic (211)
	Dihedral (8)
	Icosahedral (1)

SCOP Classification

	Multi-domain proteins (alpha and beta) (467)
	Alpha and beta proteins (a/b) (440)
	All alpha proteins (237)
	Alpha and beta proteins (a+b) (373)
	Artifacts (118)
	All beta proteins (22)
	Small proteins (3)

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1 to 25 of 2,472 Structures

Page 1 of 99

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1A5T \| pdb_00001a5t	Download File View File

CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III

Guenther, B., Onrust, R., Sali, A., O'Donnell, M., Kuriyan, J.

(1997) Cell 91: 335-345

Released	1998-05-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Escherichia coli K-12
Macromolecule	DELTA PRIME (protein)
Unique Ligands	ZN

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1B8H \| pdb_00001b8h	Download File View File

SLIDING CLAMP, DNA POLYMERASE

Shamoo, Y., Steitz, T.A.

(1999) Cell 99: 155-166

Released	1999-02-09
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia phage RB69
Macromolecule	DNA POLYMERASE PROCESSIVITY COMPONENT (protein) DNA POLYMERASE fragment (protein)

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1BGX \| pdb_00001bgx	Download File View File

TAQ POLYMERASE IN COMPLEX WITH TP7, AN INHIBITORY FAB

Murali, R., Sharkey, D.J., Daiss, J.L., Krishna Murthy, H.M.

(1998) Proc Natl Acad Sci U S A 95: 12562-12567

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Mus musculus Thermus aquaticus
Macromolecule	TAQ DNA POLYMERASE (protein) TP7 MAB (protein)

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1BNO \| pdb_00001bno	Download File View File

NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, MINIMIZED AVERAGE STRUCTURE

Liu, D.-J., Prasad, R., Wilson, S.H., Derose, E.F., Mullen, G.P.

(1996) Biochemistry 35: 6188-6200

Released	1996-12-07
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)

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1BNP \| pdb_00001bnp	Download File View File

NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA, 55 STRUCTURES

Liu, D.-J., Prasad, R., Wilson, S.H., Derose, E.F., Mullen, G.P.

(1996) Biochemistry 35: 6188-6200

Released	1996-12-07
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)

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1BPB \| pdb_00001bpb	Download File View File

CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM

Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.

(1994) Science 264: 1930-1935

Released	1994-06-22
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)

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1BPD \| pdb_00001bpd	Download File View File

CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA: EVIDENCE FOR A COMMON POLYMERASE MECHANISM

Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.

(1994) Science 264: 1930-1935

Released	1994-06-22
Method	X-RAY DIFFRACTION 3.6 Å
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)
Unique Ligands	PO4

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1BPE \| pdb_00001bpe	Download File View File

CRYSTAL STRUCTURE OF RAT DNA POLYMERASE BETA; EVIDENCE FOR A COMMON POLYMERASE MECHANISM

Sawaya, M.R., Pelletier, H., Kumar, A., Wilson, S.H., Kraut, J.

(1994) Science 264: 1930-1935

Released	1994-07-31
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)
Unique Ligands	DTP

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1BPX \| pdb_00001bpx	Download File View File

DNA POLYMERASE BETA/DNA COMPLEX

Sawaya, M.R., Prasad, R., Wilson, S.H., Kraut, J., Pelletier, H.

(1997) Biochemistry 36: 11205-11215

Released	1997-06-16
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (DNA POLYMERASE BETA) (protein) DNA (5'-D(CPCPGPAPCPGPGPCPGPCPAPTPCPAPGPC)-3') (nucleic acid) DNA (5'-D(GPCPTPGPAPTPGPCPGPC)-3') (nucleic acid) DNA (5'-D(GPTPCPGP*G)-3') (nucleic acid)
Unique Ligands	NA

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1BPY \| pdb_00001bpy	Download File View File

HUMAN DNA POLYMERASE BETA COMPLEXED WITH GAPPED DNA AND DDCTP

Sawaya, M.R., Pelletier, H., Prasad, R., Wilson, S.H., Kraut, J.

(1997) Biochemistry 36: 11205-11215

Released	1997-06-16
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens synthetic construct
Macromolecule	PROTEIN (DNA POLYMERASE BETA) (protein) DNA (5'-D(CPCPGPAPCPGPGPCPGPCPAPTPCPAPGPC)-3') (nucleic acid) DNA (5'-D(GPCPTPGPAPTPGPCPGPDOC)-3') (nucleic acid) DNA (5'-D(GPTPCPGP*G)-3') (nucleic acid)
Unique Ligands	DCT, MG, NA

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1BPZ \| pdb_00001bpz	Download File View File

HUMAN DNA POLYMERASE BETA COMPLEXED WITH NICKED DNA

Sawaya, M.R., Prasad, R., Wilson, S.H., Kraut, J., Pelletier, H.

(1997) Biochemistry 36: 11205-11215

Released	1997-06-16
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (DNA POLYMERASE BETA) (protein) DNA (5'-D(CPCPGPAPCPCPAPCPGPCPAPTPCPAPGPC)-3') (nucleic acid) DNA (5'-D(GPCPTPGPAPTPGPCPGPTPG)-3') (nucleic acid) DNA (5'-D(GPTPCPGPG)-3') (nucleic acid)
Unique Ligands	NA

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1CLQ \| pdb_00001clq	Download File View File

CRYSTAL STRUCTURE OF A REPLICATION FORK DNA POLYMERASE EDITING COMPLEX AT 2.7 A RESOLUTION

Shamoo, Y., Steitz, T.A.

(1999) Cell 99: 155-166

Released	1999-10-28
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Escherichia phage RB69
Macromolecule	PROTEIN (DNA POLYMERASE) (protein) DNA (5'-D(APGPTPAPGPTPTPCPCPGPCPG)-3') (nucleic acid) DNA (5'-D(GPCPGPGPAPAPCPTPAPCP*T)-3') (nucleic acid)
Unique Ligands	CA, GDP

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1D1U \| pdb_00001d1u	Download File View File

USE OF AN N-TERMINAL FRAGMENT FROM MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE TO FACILITATE CRYSTALLIZATION AND ANALYSIS OF A PSEUDO-16-MER DNA MOLECULE CONTAINING G-A MISPAIRS

Cote, M.L., Yohannan, S., Georgiadis, M.M.

(2000) Acta Crystallogr D Biol Crystallogr 56: 1120-1131

Released	2000-04-02
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Moloney murine leukemia virus
Macromolecule	PROTEIN (REVERSE TRANSCRIPTASE) (protein) DNA (5'-D(APCPGPGPCPAPCPGPAPG)-3') (nucleic acid) DNA (5'-D(CPTPCPGPTPG)-3') (nucleic acid)

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1D5A \| pdb_00001d5a	Download File View File

CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM

Zhao, Y., Jeruzalmi, D., Leighton, L., Lasken, R., Kuriyan, J.

(1999) Structure 7: 1189-1199

Released	2000-03-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Desulfurococcus sp. Tok
Macromolecule	PROTEIN (DNA POLYMERASE) (protein)
Unique Ligands	MG, SO4

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1D8Y \| pdb_00001d8y	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA

Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.

(1999) Proc Natl Acad Sci U S A 96: 14240-14245

Released	1999-12-02
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE I (protein) D(T)19 OLIGOMER (nucleic acid)
Unique Ligands	SO4, ZN

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1D9D \| pdb_00001d9d	Download File View File

CRYSTALL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH SHORT DNA FRAGMENT CARRYING 2'-0-AMINOPROPYL-RNA MODIFICATIONS 5'-D(TCG)-AP(AUC)-3'

Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.

(1999) Proc Natl Acad Sci U S A 96: 14240-14245

Released	1999-12-02
Method	X-RAY DIFFRACTION 2.18 Å
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE I (protein) 5'-D(TPCPGP)-R(AP(U31)P*(C31))-3' (hybrid)
Unique Ligands	MG, SO4, ZN

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1D9F \| pdb_00001d9f	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA TETRAMER CARRYING 2'-O-(3-AMINOPROPYL)-RNA MODIFICATION 5'-D(TT)-AP(U)-D(T)-3'

Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.

(1999) Proc Natl Acad Sci U S A 96: 14240-14245

Released	1999-12-02
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE I (protein) DNA/RNA (5'-D(TPTP)-R((U31)P)-D(T)-3') (hybrid)
Unique Ligands	SO4, ZN

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1DK2 \| pdb_00001dk2	Download File View File

REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA

Maciejewski, M.W., Prasad, R., Liu, D.-J., Wilson, S.H., Mullen, G.P.

(2000) J Mol Biology 296: 229-253

Released	2000-02-14
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)

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1DK3 \| pdb_00001dk3	Download File View File

REFINED SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF DNA POLYMERASE BETA

Maciejewski, M.W., Prasad, R., Liu, D.-J., Wilson, S.H., Mullen, G.P.

(2000) J Mol Biology 296: 229-253

Released	2000-02-14
Method	SOLUTION NMR
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein)

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1DML \| pdb_00001dml	Download File View File

CRYSTAL STRUCTURE OF HERPES SIMPLEX UL42 BOUND TO THE C-TERMINUS OF HSV POL

Zuccola, H.J., Filman, D.J., Coen, D.M., Hogle, J.M.

(2000) Mol Cell 5: 267-278

Released	2000-03-15
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Human alphaherpesvirus 1
Macromolecule	DNA POLYMERASE (protein) DNA POLYMERASE PROCESSIVITY FACTOR (protein)

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1DPI \| pdb_00001dpi	Download File View File

STRUCTURE OF LARGE FRAGMENT OF ESCHERICHIA COLI DNA POLYMERASE I COMPLEXED WITH D/TMP

Beese, L., Ollis, D., Steitz, T.

(1985) Nature 313: 762-766

Released	1987-10-16
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE I KLENOW FRAGMENT (protein)
Unique Ligands	ZN

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1DU2 \| pdb_00001du2	Download File View File

SOLUTION STRUCTURE OF THE THETA SUBUNIT OF DNA POLYMERASE III

Keniry, M.A., Berthon, H.A., Yang, J.-Y., Miles, C.S., Dixon, N.E.

(2000) Protein Sci 9: 721-723

Released	2000-05-31
Method	SOLUTION NMR
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE III (protein)

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1EM8 \| pdb_00001em8	Download File View File

Crystal structure of chi and psi subunit heterodimer from DNA POL III

Gulbis, J.M., Finkelstein, J., O'Donnell, M., Kuriyan, J.

(2004) Eur J Biochem 271: 439-449

Released	2003-08-26
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	DNA POLYMERASE III CHI SUBUNIT (protein) DNA POLYMERASE III PSI SUBUNIT (protein)

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1H15 \| pdb_00001h15	Download File View File

X-ray crystal structure of HLA-DRA10101/DRB50101 complexed with a peptide from Epstein Barr Virus DNA polymerase

Lang, H., Jacobsen, H., Ikemizu, S., Andersson, C., Harlos, K., Madsen, L., Hjorth, P., Sondergaard, L., Svejgaard, A., Wucherpfennig, K., Stuart, D.I., Bell, J.I., Jones, E.Y., Fugger, L.

(2002) Nat Immunol 3: 940

Released	2002-10-03
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Homo sapiens human gammaherpesvirus 4
Macromolecule	DNA POLYMERASE (protein) HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN (protein) HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAIN (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

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1HUO \| pdb_00001huo	Download File View File

CRYSTAL STRUCTURE OF DNA POLYMERASE BETA COMPLEXED WITH DNA AND CR-TMPPCP

Arndt, J.W., Gong, W., Zhong, X., Showalter, A.K., Liu, J., Lin, Z., Paxson, C., Tsai, M.-D., Chan, M.K.

(2001) Biochemistry 40: 5368-5375

Released	2001-04-23
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Rattus norvegicus
Macromolecule	DNA POLYMERASE BETA (protein) 5'-D(APAPTPAPGPGPCPGPTPCPG)-3' (nucleic acid) 5'-D(PCPGPAPCPGPCPC)-3' (nucleic acid)
Unique Ligands	CR, TTE

1 to 25 of 2,472 Structures

Page 1 of 99

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1A5T | pdb_00001a5t

1B8H | pdb_00001b8h

1BGX | pdb_00001bgx

1BNO | pdb_00001bno

1BNP | pdb_00001bnp

1BPB | pdb_00001bpb

1BPD | pdb_00001bpd

1BPE | pdb_00001bpe

1BPX | pdb_00001bpx

1BPY | pdb_00001bpy

1BPZ | pdb_00001bpz

1CLQ | pdb_00001clq

1D1U | pdb_00001d1u

1D5A | pdb_00001d5a

1D8Y | pdb_00001d8y

1D9D | pdb_00001d9d

1D9F | pdb_00001d9f

1DK2 | pdb_00001dk2

1DK3 | pdb_00001dk3

1DML | pdb_00001dml

1DPI | pdb_00001dpi

1DU2 | pdb_00001du2

1EM8 | pdb_00001em8

1H15 | pdb_00001h15

1HUO | pdb_00001huo