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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 2.7.10.1

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Search Summary

This query matches 2,276 Structures.

Refinements

Structure Determination Methodology

experimental (2,276)

Scientific Name of Source Organism

	Homo sapiens (958)
	Escherichia coli (83)
	Mus musculus (75)
	Escherichia coli K-12 (73)
	Sporosarcina pasteurii (35)
	Rattus norvegicus (30)
	synthetic construct (30)
	Klebsiella aerogenes (26)
	Nitratidesulfovibrio vulgaris str. Hildenborough (21)
	Pseudomonas aeruginosa (19)

More...

Taxonomy

	Eukaryota (1,242)
	Bacteria (923)
	Archaea (50)
	Riboviria (32)
	other sequences (30)
	Duplodnaviria (23)
	Eukaryota (eukaryotes) (8)
	Varidnaviria (6)
	unclassified sequences (6)
	Adnaviria (4)

More...

Experimental Method

	X-RAY DIFFRACTION (2,243)
	ELECTRON MICROSCOPY (27)
	SOLUTION NMR (5)
	NEUTRON DIFFRACTION (4)

Polymer Entity Type

	Protein (2,265)
	DNA (41)
	RNA (11)

Refinement Resolution (Å)

	0.5 - 1.0 (6)
	1.0 - 1.5 (471)
	1.5 - 2.0 (814)
	2.0 - 2.5 (584)
	2.5 - 3.0 (280)
	3.0 - 3.5 (96)
	3.5 - 4.0 (12)
	4.0 - 4.5 (5)
	> 4.5 (3)

Release Date

	1990 - 1994 (3)
	1995 - 1999 (41)
	2000 - 2004 (123)
	2005 - 2009 (255)
	2010 - 2014 (430)
	2015 - 2019 (993)
	2020 - 2024 (409)
	2025 - 2029 (22)

Enzyme Classification Name

	Oxidoreductases (625)
	Hydrolases (722)
	Transferases (193)
	Lyases (115)
	Isomerases (36)
	Ligases (23)
	Translocases (3)

Membrane Protein Annotation

	PDBTM (48)
	mpstruc (39)
	MemProtMD (41)
	OPM (26)

Symmetry Type

	Asymmetric (1,577)
	Cyclic (628)
	Dihedral (115)
	Octahedral (14)
	Tetrahedral (13)
	Helical (1)

SCOP Classification

	All beta proteins (568)
	Alpha and beta proteins (a+b) (547)
	All alpha proteins (153)
	Alpha and beta proteins (a/b) (198)
	Artifacts (206)
	Multi-domain proteins (alpha and beta) (91)
	Small proteins (16)
	Membrane and cell surface proteins and peptides (14)
	Coiled coil proteins (3)
	Designed proteins (1)

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AllSelected

1 to 25 of 2,276 Structures

Page 1 of 92

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1A5N \| pdb_00001a5n	Download File View File

K217A VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL

Pearson, M.A., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(1998) Biochemistry 37: 6214-6220

Released	1998-05-27
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE (ALPHA SUBUNIT) (protein) UREASE (BETA SUBUNIT) (protein) UREASE (GAMMA SUBUNIT) (protein)
Unique Ligands	FMT, NI

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1A5O \| pdb_00001a5o	Download File View File

K217C VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL

Pearson, M.A., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(1998) Biochemistry 37: 6214-6220

Released	1998-05-27
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE (ALPHA SUBUNIT) (protein) UREASE (BETA SUBUNIT) (protein) UREASE (GAMMA SUBUNIT) (protein)
Unique Ligands	FMT, NI

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1B9M \| pdb_00001b9m	Download File View File

REGULATOR FROM ESCHERICHIA COLI

Hall, D.R., Gourley, D.G., Hunter, W.N.

(1999) EMBO J 18: 1435-1436

Released	2000-03-15
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Escherichia coli
Macromolecule	PROTEIN (MODE) (protein)
Unique Ligands	NI

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1B9N \| pdb_00001b9n	Download File View File

REGULATOR FROM ESCHERICHIA COLI

Hall, D.R., Gourley, D.G., Hunter, W.N.

(1999) EMBO J 18: 1435-1446

Released	2000-03-15
Method	X-RAY DIFFRACTION 2.09 Å
Organisms	Escherichia coli
Macromolecule	PROTEIN (MODE) (protein)
Unique Ligands	NI

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1BS6 \| pdb_00001bs6	Download File View File

PEPTIDE DEFORMYLASE AS NI2+ CONTAINING FORM IN COMPLEX WITH TRIPEPTIDE MET-ALA-SER

Becker, A., Schlichting, I., Kabsch, W., Groche, D., Schultz, S., Wagner, A.F.V.

(1998) Nat Struct Biol 5: 1053-1058

Released	1999-08-27
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	PROTEIN (MET-ALA-SER) (protein) PROTEIN (PEPTIDE DEFORMYLASE) (protein)
Unique Ligands	NI, SO4

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1BS7 \| pdb_00001bs7	Download File View File

PEPTIDE DEFORMYLASE AS NI2+ CONTAINING FORM

Becker, A., Schlichting, I., Kabsch, W., Groche, D., Schultz, S., Wagner, A.F.V.

(1998) J Biological Chem 273: 11413-11416

Released	1999-08-27
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Escherichia coli
Macromolecule	PROTEIN (PEPTIDE DEFORMYLASE) (protein)
Unique Ligands	NI, SO4

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1BXI \| pdb_00001bxi	Download File View File

CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9

Kuhlmann, U.C., Kleanthous, C., James, R., Moore, G.R., Hemmings, A.M.

(1998) Thesis

Released	1999-10-04
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Escherichia coli
Macromolecule	PROTEIN (COLICIN E9 IMMUNITY PROTEIN) (protein) PROTEIN (COLICIN E9) (protein)
Unique Ligands	NI, PO4

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1CC1 \| pdb_00001cc1	Download File View File

CRYSTAL STRUCTURE OF A REDUCED, ACTIVE FORM OF THE NI-FE-SE HYDROGENASE FROM DESULFOMICROBIUM BACULATUM

Garcin, E., Vernede, X., Hatchikian, E.C., Volbeda, A., Frey, M., Fontecilla-Camps, J.C.

(1999) Structure 7: 557-566

Released	1999-06-01
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Desulfomicrobium baculatum
Macromolecule	HYDROGENASE (LARGE SUBUNIT) (protein) HYDROGENASE (SMALL SUBUNIT) (protein)
Unique Ligands	FCO, FE2, H2S, NI, SF4

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1DDN \| pdb_00001ddn	Download File View File

DIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX

White, A., Ding, X., Vanderspek, J.C., Murphy, J.R., Ringe, D.

(1998) Nature 394: 502-506

Released	1998-10-14
Method	X-RAY DIFFRACTION 3 Å
Organisms	Corynebacterium diphtheriae
Macromolecule	DIPHTHERIA TOX REPRESSOR (protein) 33 BASE DNA CONTAINING TOXIN OPERATOR (nucleic acid)
Unique Ligands	NI

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1E0O \| pdb_00001e0o	Download File View File

CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX

Pellegrini, L., Burke, D.F., von Delft, F., Mulloy, B., Blundell, T.L.

(2000) Nature 407: 1029

Released	2000-10-23
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	FIBROBLAST GROWTH FACTOR 1 (protein) FIBROBLAST GROWTH FACTOR RECEPTOR 2 (protein)
Unique Ligands	NI, SO4
Unique branched monosaccharides	IDS, SGN

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1E20 \| pdb_00001e20	Download File View File

The FMN binding protein AtHal3

Albert, A., Martinez-Ripoll, M., Espinosa-Ruiz, A., Yenush, L., Culianez-Macia, F.A., Serrano, R.

(2000) Structure 8: 961

Released	2000-09-11
Method	X-RAY DIFFRACTION 2.02 Å
Organisms	Arabidopsis thaliana
Macromolecule	HALOTOLERANCE PROTEIN HAL3 (protein)
Unique Ligands	BME, FMN, NI

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1E42 \| pdb_00001e42	Download File View File

Beta2-adaptin appendage domain, from clathrin adaptor AP2

Owen, D.J., Evans, P.R., McMahon, H.T.

(2000) EMBO J 19: 4216

Released	2000-08-21
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	AP-2 COMPLEX SUBUNIT BETA (protein)
Unique Ligands	CL, DTD, GOL, MG, NI

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1E4W \| pdb_00001e4w	Download File View File

crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment

Hahn, M., Winkler, D., Misselwitz, R., Wessner, H., Welfle, K., Zahn, G., Schneider-Mergener, J., Hoehne, W.

(2001) J Mol Biology 314: 293

Released	2001-07-12
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Mus musculus synthetic construct
Macromolecule	CYCLIC PEPTIDE (protein) TAB2 (protein)
Unique Ligands	CL, NI

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1E9Y \| pdb_00001e9y	Download File View File

Crystal structure of Helicobacter pylori urease in complex with acetohydroxamic acid

Ha, N.-C., Oh, S.-T., Oh, B.-H.

(2001) Nat Struct Biol 8: 480

Released	2001-11-01
Method	X-RAY DIFFRACTION 3 Å
Organisms	Helicobacter pylori
Macromolecule	UREASE SUBUNIT ALPHA (protein) UREASE SUBUNIT BETA (protein)
Unique Ligands	HAE, NI

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1E9Z \| pdb_00001e9z	Download File View File

Crystal structure of Helicobacter pylori urease

Ha, N.-C., Oh, S.-T., Oh, B.-H.

(2001) Nat Struct Biol 8: 480

Released	2001-11-01
Method	X-RAY DIFFRACTION 3 Å
Organisms	Helicobacter pylori
Macromolecule	UREASE SUBUNIT ALPHA (protein) UREASE SUBUNIT BETA (protein)
Unique Ligands	NI

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1EF8 \| pdb_00001ef8	Download File View File

CRYSTAL STRUCTURE OF METHYLMALONYL COA DECARBOXYLASE

Benning, M.M., Haller, T., Gerlt, J.A., Holden, H.M.

(2000) Biochemistry 39: 4630-4639

Released	2000-05-24
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Escherichia coli
Macromolecule	METHYLMALONYL COA DECARBOXYLASE (protein)
Unique Ligands	NI

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1EJE \| pdb_00001eje	Download File View File

CRYSTAL STRUCTURE OF AN FMN-BINDING PROTEIN

Christendat, D., Saridakis, V., Bochkarev, A., Arrowsmith, C., Edwards, A.M., Northeast Structural Genomics Consortium (NESG)

(2000) Nat Struct Biol 7: 903-909

Released	2000-10-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	FMN-BINDING PROTEIN (protein)
Unique Ligands	FMN, NI, SO4

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1EJR \| pdb_00001ejr	Download File View File

CRYSTAL STRUCTURE OF THE D221A VARIANT OF KLEBSIELLA AEROGENES UREASE

Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(2000) Biochemistry 39: 8575-8584

Released	2000-09-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJS \| pdb_00001ejs	Download File View File

Crystal Structure of the H219N Variant of Klebsiella Aerogenes Urease

Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(2000) Biochemistry 39: 8575-8584

Released	2000-09-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJT \| pdb_00001ejt	Download File View File

CRYSTAL STRUCTURE OF THE H219Q VARIANT OF KLEBSIELLA AEROGENES UREASE

Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(2000) Biochemistry 39: 8575-8584

Released	2000-09-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJU \| pdb_00001eju	Download File View File

CRYSTAL STRUCTURE OF THE H320N VARIANT OF KLEBSIELLA AEROGENES UREASE

Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(2000) Biochemistry 39: 8575-8584

Released	2000-09-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJV \| pdb_00001ejv	Download File View File

CRYSTAL STRUCTURE OF THE H320Q VARIANT OF KLEBSIELLA AEROGENES UREASE

Pearson, M.A., Park, I.S., Schaller, R.A., Michel, L.O., Karplus, P.A., Hausinger, R.P.

(2000) Biochemistry 39: 8575-8584

Released	2000-09-08
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJW \| pdb_00001ejw	Download File View File

CRYSTAL STRUCTURE OF WILD-TYPE KLEBSIELLA AEROGENES UREASE AT 298K

Pearson, M.A., Karplus, P.A.

To be published

Released	2003-11-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EJX \| pdb_00001ejx	Download File View File

CRYSTAL STRUCTURE OF WILD-TYPE KLEBSIELLA AEROGENES UREASE AT 100K

Pearson, M.A., Karplus, P.A.

To be published

Released	2003-07-08
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Klebsiella aerogenes
Macromolecule	UREASE ALPHA SUBUNIT (protein) UREASE BETA SUBUNIT (protein) UREASE GAMMA SUBUNIT (protein)
Unique Ligands	NI

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1EK0 \| pdb_00001ek0	Download File View File

GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION

Esters, H., Scheidig, A.J.

(2000) J Mol Biology 298: 111-121

Released	2000-04-17
Method	X-RAY DIFFRACTION 1.48 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	PROTEIN (GTP-BINDING PROTEIN YPT51) (protein)
Unique Ligands	GDP, GNP, MG, NI

1 to 25 of 2,276 Structures

Page 1 of 92

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1A5N | pdb_00001a5n

1A5O | pdb_00001a5o

1B9M | pdb_00001b9m

1B9N | pdb_00001b9n

1BS6 | pdb_00001bs6

1BS7 | pdb_00001bs7

1BXI | pdb_00001bxi

1CC1 | pdb_00001cc1

1DDN | pdb_00001ddn

1E0O | pdb_00001e0o

1E20 | pdb_00001e20

1E42 | pdb_00001e42

1E4W | pdb_00001e4w

1E9Y | pdb_00001e9y

1E9Z | pdb_00001e9z

1EF8 | pdb_00001ef8

1EJE | pdb_00001eje

1EJR | pdb_00001ejr

1EJS | pdb_00001ejs

1EJT | pdb_00001ejt

1EJU | pdb_00001eju

1EJV | pdb_00001ejv

1EJW | pdb_00001ejw

1EJX | pdb_00001ejx

1EK0 | pdb_00001ek0