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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Gene Name = "Coro1"

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Search Summary

This query matches 104 Structures.

Refinements

Structure Determination Methodology

experimental (104)

Scientific Name of Source Organism

Homo sapiens (104)

Taxonomy

Eukaryota (104)

Experimental Method

X-RAY DIFFRACTION (104)

Polymer Entity Type

Protein (104)

Refinement Resolution (Å)

	1.0 - 1.5 (8)
	1.5 - 2.0 (47)
	2.0 - 2.5 (43)
	2.5 - 3.0 (6)

Release Date

	2005 - 2009 (11)
	2010 - 2014 (43)
	2015 - 2019 (23)
	2020 - 2024 (27)

Enzyme Classification Name

Transferases (104)

Symmetry Type

Asymmetric (104)

SCOP Classification

Alpha and beta proteins (a+b) (92)

AllSelected

1 to 25 of 104 Structures

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1ZLT \| pdb_00001zlt	Download File View File

Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog

Lee, C.C., Ng, K., Wan, Y., Gray, N., Spraggon, G.

To be published

Released	2006-06-27
Method	X-RAY DIFFRACTION 1.74 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	HYM, SO4

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1ZYS \| pdb_00001zys	Download File View File

Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor

Stavenger, R.A., Zhao, B., Zhou, B.-B.S., Brown, M.J., Lee, D., Holt, D.A.

To be published

Released	2006-06-13
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein) pentapeptide fragment (protein)
Unique Ligands	199, SO4

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2AYP \| pdb_00002ayp	Download File View File

Crystal Structure of CHK1 with an Indol Inhibitor

Lin, N.-H., Xia, P., Kovar, P., Chen, Z., Zhang, H., Rosenberg, S.H., Sham, H.L.

(2006) Bioorg Med Chem Lett 16: 421-426

Released	2006-09-12
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	43A

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2HOG \| pdb_00002hog	Download File View File

crystal structure of Chek1 in complex with inhibitor 20

Yan, Y., Ikuta, M.

(2006) Bioorg Med Chem Lett 16: 6049-6053

Released	2007-04-24
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	710

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2HXL \| pdb_00002hxl	Download File View File

crystal structure of Chek1 in complex with inhibitor 1

Yan, Y.

(2006) Bioorg Med Chem Lett 16: 5907-5912

Released	2007-06-19
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	422

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2HXQ \| pdb_00002hxq	Download File View File

crystal structure of Chek1 in complex with inhibitor 2

Yan, Y.

(2006) Bioorg Med Chem Lett 16: 5907-5912

Released	2007-06-19
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	373

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2HY0 \| pdb_00002hy0	Download File View File

crystal structure of chek1 in complex with inhibitor 22

Yan, Y.

(2006) Bioorg Med Chem Lett 16: 5907-5912

Released	2007-06-19
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	306

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2YWP \| pdb_00002ywp	Download File View File

Crystal Structure of CHK1 with a Urea Inhibitor

Park, C.

(2006) Bioorg Med Chem Lett 16: 2293-2298

Released	2007-05-08
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	A42

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3F9N \| pdb_00003f9n	Download File View File

Crystal structure of chk1 kinase in complex with inhibitor 38

Yan, Y., Munshi, S., Ikuta, M.

(2009) Bioorg Med Chem Lett 19: 1240-1244

Released	2009-01-20
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	38M, SO4

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3JVR \| pdb_00003jvr	Download File View File

Characterization of the Chk1 allosteric inhibitor binding site

Chen, P.

(2009) Biochemistry 48: 9823-9830

Released	2009-10-06
Method	X-RAY DIFFRACTION 1.76 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	AGX

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3JVS \| pdb_00003jvs	Download File View File

Characterization of the Chk1 allosteric inhibitor binding site

Chen, P.

(2009) Biochemistry 48: 9823-9830

Released	2009-10-06
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	AGY

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3OT3 \| pdb_00003ot3	Download File View File

X-ray crystal structure of compound 22k bound to human Chk1 kinase domain

Fischmann, T.O.

(2011) Bioorg Med Chem Lett 21: 471-474

Released	2010-11-10
Method	X-RAY DIFFRACTION 1.44 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	22K

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3OT8 \| pdb_00003ot8	Download File View File

X-ray crystal structure of compound 17r bound to human Chk1 kinase domain

Fischmann, T.O.

(2011) Bioorg Med Chem Lett 21: 467-470

Released	2010-11-10
Method	X-RAY DIFFRACTION 1.6455 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	GOL, MI5

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3PA3 \| pdb_00003pa3	Download File View File

X-ray crystal structure of compound 70 bound to human CHK1 kinase domain

Fischmann, T.O.

(2010) Bioorg Med Chem Lett 20: 7216-7221

Released	2010-12-08
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	C70

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3PA4 \| pdb_00003pa4	Download File View File

X-ray crystal structure of compound 2a bound to human CHK1 kinase domain

Fischmann, T.O.

(2010) Bioorg Med Chem Lett 20: 7216-7221

Released	2010-12-08
Method	X-RAY DIFFRACTION 1.59 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	C72, GOL

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3PA5 \| pdb_00003pa5	Download File View File

X-ray crystal structure of compound 1 bound to human CHK1 kinase domain

Fischmann, T.O.

(2010) Bioorg Med Chem Lett 20: 7216-7221

Released	2010-12-08
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	C73, GOL

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3TKH \| pdb_00003tkh	Download File View File

Crystal structure of Chk1 in complex with inhibitor S01

Yan, Y., Ikuta, M.

(2012) Bioorg Med Chem Lett 22: 2609-2612

Released	2012-04-11
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	07S, SO4

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3TKI \| pdb_00003tki	Download File View File

Crystal structure of Chk1 in complex with inhibitor S25

Yan, Y., Ikuta, M.

(2012) Bioorg Med Chem Lett 22: 2609-2612

Released	2012-04-11
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	S25, SO4

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3U9N \| pdb_00003u9n	Download File View File

X-ray crystal structure of compound 1 bound to human CHK1 kinase domain

Fischmann, T.O.

(2012) ACS Med Chem Lett

Released	2012-01-25
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	09H

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4FSM \| pdb_00004fsm	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	GOL, HK1, IPA, SO4

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4FSN \| pdb_00004fsn	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	A58, IPA, SO4

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4FSQ \| pdb_00004fsq	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	HK3, SO4

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4FSR \| pdb_00004fsr	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	HKC, SO4

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4FST \| pdb_00004fst	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	GOL, HK4, IPA, SO4

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4FSU \| pdb_00004fsu	Download File View File

Crystal Structure of the CHK1

Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.

To be published

Released	2012-08-22
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein kinase Chk1 (protein)
Unique Ligands	GOL, HK5, IPA, SO4

1 to 25 of 104 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1ZLT | pdb_00001zlt

1ZYS | pdb_00001zys

2AYP | pdb_00002ayp

2HOG | pdb_00002hog

2HXL | pdb_00002hxl

2HXQ | pdb_00002hxq

2HY0 | pdb_00002hy0

2YWP | pdb_00002ywp

3F9N | pdb_00003f9n

3JVR | pdb_00003jvr

3JVS | pdb_00003jvs

3OT3 | pdb_00003ot3

3OT8 | pdb_00003ot8

3PA3 | pdb_00003pa3

3PA4 | pdb_00003pa4

3PA5 | pdb_00003pa5

3TKH | pdb_00003tkh

3TKI | pdb_00003tki

3U9N | pdb_00003u9n

4FSM | pdb_00004fsm

4FSN | pdb_00004fsn

4FSQ | pdb_00004fsq

4FSR | pdb_00004fsr

4FST | pdb_00004fst

4FSU | pdb_00004fsu