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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Ye, H."

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Search Summary

This query matches 75 Structures.

Refinements

Structure Determination Methodology

experimental (75)

Scientific Name of Source Organism

	Homo sapiens (25)
	Human immunodeficiency virus 1 (18)
	Human immunodeficiency virus type 1 BH10 (11)
	Gallus gallus (9)
	Rattus norvegicus (9)
	Sus scrofa (8)
	Mus musculus (3)
	Human coronavirus 229E (2)
	Plasmodium falciparum 3D7 (2)
	Severe acute respiratory syndrome coronavirus 2 (2)

More...

Taxonomy

	Eukaryota (47)
	Riboviria (29)
	Eukaryota (eukaryotes) (5)
	Archaea (1)
	Bacteria (1)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (70)
	SOLUTION NMR (4)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

	Protein (75)
	DNA (8)
	RNA (1)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (8)
	2.0 - 2.5 (27)
	2.5 - 3.0 (28)
	3.0 - 3.5 (6)

Release Date

	2000 - 2004 (18)
	2005 - 2009 (18)
	2010 - 2014 (7)
	2015 - 2019 (16)
	2020 - 2024 (16)

Enzyme Classification Name

	Transferases (39)
	Hydrolases (20)
	Oxidoreductases (4)
	Isomerases (3)
	Ligases (1)

Membrane Protein Annotation

	OPM (2)
	MemProtMD (1)
	PDBTM (1)

Symmetry Type

	Asymmetric (62)
	Cyclic (15)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a+b) (22)
	Alpha and beta proteins (a/b) (26)
	All beta proteins (17)
	Coiled coil proteins (7)
	Multi-domain proteins (alpha and beta) (16)
	Artifacts (17)
	All alpha proteins (15)
	Membrane and cell surface proteins and peptides (1)

AllSelected

1 to 25 of 75 Structures

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1CZY \| pdb_00001czy	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE TRAF DOMAIN OF HUMAN TRAF2 AND AN LMP1 BINDING PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Epstein-Barr virus (strain B95-8) Homo sapiens
Macromolecule	LATENT MEMBRANE PROTEIN 1 (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1CZZ \| pdb_00001czz	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 17-RESIDUE CD40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	CD 40 PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D00 \| pdb_00001d00	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 5-RESIDUE CD40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-29
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	B-CELL SURFACE ANTIGEN CD40 (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D01 \| pdb_00001d01	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A HUMAN CD30 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2003-12-02
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	CD30 PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2 (protein)

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1D0A \| pdb_00001d0a	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2) IN COMPLEX WITH A HUMAN OX40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	OX40L RECEPTOR PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D0J \| pdb_00001d0j	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A M4-1BB PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	4-1BB LIGAND RECEPTOR (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1F3V \| pdb_00001f3v	Download File View File

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2

Park, Y.C., Ye, H., Hsia, C., Segal, D., Rich, R., Liou, H.-C., Myszka, D., Wu, H.

(2000) Cell 101: 777-787

Released	2000-09-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN (protein) TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEIN (protein)

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1LB4 \| pdb_00001lb4	Download File View File

TRAF6 apo structure

Ye, H., Arron, J.R., Lamothe, B., Cirilli, M., Kobayashi, T., Shevde, N.K., Segal, D., Dzivenu, O., Vologodskaia, M., Yim, M., Du, K., Singh, S., Pike, J.W., Darnay, B.G., Choi, Y., Wu, H.

(2002) Nature 418: 443-447

Released	2002-07-31
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	TNF receptor-associated factor 6 (protein)

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1LB5 \| pdb_00001lb5	Download File View File

TRAF6-RANK Complex

Ye, H., Arron, J.R., Lamothe, B., Cirilli, M., Kobayashi, T., Shevde, N.K., Segal, D., Dzivenu, O., Vologodskaia, M., Yim, M., Du, K., Singh, S., Pike, J.W., Darnay, B.G., Choi, Y., Wu, H.

(2002) Nature 418: 443-447

Released	2002-07-31
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	TNF receptor-associated factor 6 (protein) receptor activator of nuclear factor-kappa B (protein)

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1LB6 \| pdb_00001lb6	Download File View File

TRAF6-CD40 Complex

Ye, H., Arron, J.R., Lamothe, B., Cirilli, M., Kobayashi, T., Shevde, N.K., Segal, D., Dzivenu, O., Vologodskaia, M., Yim, M., Du, K., Singh, S., Pike, J.W., Darnay, B.G., Choi, Y., Wu, H.

(2002) Nature 418: 443-447

Released	2002-07-31
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	CD40 antigen (protein) TNF receptor-associated factor 6 (protein)

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1M6I \| pdb_00001m6i	Download File View File

Crystal Structure of Apoptosis Inducing Factor (AIF)

Ye, H., Cande, C., Stephanou, N.C., Jiang, S., Gurbuxani, S., Larochette, N., Daugas, E., Garrido, C., Kroemer, G., Wu, H.

(2002) Nat Struct Biol 9: 680-684

Released	2002-08-28
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Programmed cell death protein 8 (protein)
Unique Ligands	FAD

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1PM3 \| pdb_00001pm3	Download File View File

MTH1859

Ye, H., Steegborn, C., Wu, H., Northeast Structural Genomics Consortium (NESG)

(2004) J Struct Biol 148: 251-256

Released	2003-08-12
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	MTH1895 (protein)

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1S6P \| pdb_00001s6p	Download File View File

CRYSTAL STRUCTURE OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R100943

Das, K., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	POL polyprotein [Contains: Reverse transcriptase] (protein)
Unique Ligands	IET, MG

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1S6Q \| pdb_00001s6q	Download File View File

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681

Das, K., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 3 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	POL polyprotein [Contains: Reverse transcriptase] (protein)
Unique Ligands	TPB

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1S9E \| pdb_00001s9e	Download File View File

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R129385

Das, K., Clark Jr., A.D., Ludovici, D.W., Kukla, M.J., Decorte, B., Lewi, P.J., Hughes, S.H., Janssen, P.A., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	POL polyprotein [Contains: Reverse transcriptase] (protein) POL polyprotein [Contains:Reverse transcriptase] (protein)
Unique Ligands	ADB

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1S9G \| pdb_00001s9g	Download File View File

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R120394.

Das, K., Clark Jr., A.D., Ludovici, D.W., Kukla, M.J., Decorte, B., Lewi, P.J., Hughes, S.H., Janssen, P.A., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	POL polyprotein [Contains: Reverse transcriptase] (protein)
Unique Ligands	ABZ

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1SUQ \| pdb_00001suq	Download File View File

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R185545

Das, K., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 3 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	REVERSE TRANSCRIPTASE (protein)
Unique Ligands	185, MG

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1SV5 \| pdb_00001sv5	Download File View File

CRYSTAL STRUCTURE OF K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R165335

Das, K., Arnold, E.

(2004) J Med Chem 47: 2550-2560

Released	2004-05-11
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	Reverse Transcriptase (protein)
Unique Ligands	65B

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2B5J \| pdb_00002b5j	Download File View File

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R165481

Himmel, D.H., Das, K., Clark Jr., A.D., Hughes, S.H., Benjahad, A., Oumouch, S., Guillemont, J., Coupa, S., Poncelet, A., Csoka, I., Meyer, C., Andries, K., Mguyen, C.H., Grierson, D.S., Arnold, E.

(2005) J Med Chem 48: 7582-7591

Released	2005-12-06
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	Reverse transcriptase P51 SUBUNIT (protein) Reverse transcriptase P66 SUBUNIT (protein)
Unique Ligands	3AC, MN

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2BAN \| pdb_00002ban	Download File View File

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R157208

Das, K., Arnold, E.

(2005) J Med Chem 48: 7582-7591

Released	2005-12-06
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	Reverse transcriptase P51 subunit (protein) Reverse transcriptase P66 subunit (protein)
Unique Ligands	357, MN

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2BE2 \| pdb_00002be2	Download File View File

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239

Himmel, D.M., Das, K., Clark Jr., A.D., Hughes, S.H., Benjahad, A., Oumouch, S., Guillemont, J., Coupa, S., Poncelet, A., Csoka, I., Meyer, C., Andries, K., Nguyen, C.H., Grierson, D.S., Arnold, E.

(2005) J Med Chem 48: 7582-7591

Released	2005-12-06
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	REVERSE TRANSCRIPTASE P51 SUBUNIT (protein) REVERSE TRANSCRIPTASE P66 SUBUNIT (protein)
Unique Ligands	GOL, MN, R22
Unique branched monosaccharides	FRU, GLC

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2I5J \| pdb_00002i5j	Download File View File

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor

Himmel, D.M., Sarafianos, S.G., Knight, J.L., Levy, R.M., Arnold, E.

(2006) ACS Chem Biol 1: 702-712

Released	2006-12-05
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	Reverse transcriptase/ribonuclease H P51 subunit (protein) Reverse transcriptase/ribonuclease H P66 subunit (protein)
Unique Ligands	GLC, K05, MG
Unique branched monosaccharides	FRU, GLC

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2IAJ \| pdb_00002iaj	Download File View File

Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with ATP

Das, K., Arnold, E.

(2007) J Mol Biology 365: 77-89

Released	2006-12-19
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Human immunodeficiency virus type 1 BH10
Macromolecule	Reverse transcriptase/ribonuclease H (p66 RT) (protein) Reverse transcriptase/ribonuclease H; p51 RT (protein)
Unique Ligands	ATP, GOL, MN, NA

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2IC3 \| pdb_00002ic3	Download File View File

Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with Nonnucleoside Inhibitor HBY 097

Das, K., Arnold, E.

(2007) J Mol Biology 365: 77-89

Released	2006-12-19
Method	X-RAY DIFFRACTION 3 Å
Organisms	Human immunodeficiency virus type 1 BH10
Macromolecule	Reverse transcriptase/ribonuclease H (p51 RT) (protein) Reverse transcriptase/ribonuclease H (p66 RT) (protein)
Unique Ligands	HBY, MN