RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Citation Author = "Westaway, S.M."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 20 Structures.

Refinements

Structure Determination Methodology

experimental (20)

Scientific Name of Source Organism

Homo sapiens (20)

Taxonomy

Eukaryota (20)

Experimental Method

X-RAY DIFFRACTION (20)

Polymer Entity Type

Protein (20)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (4)
	2.0 - 2.5 (11)
	2.5 - 3.0 (4)

Release Date

2015 - 2019 (20)

Enzyme Classification Name

Oxidoreductases (20)

Symmetry Type

	Asymmetric (18)
	Cyclic (2)

SCOP Classification

	All beta proteins (19)
	Artifacts (1)
	Small proteins (1)

AllSelected

1 to 20 of 20 Structures

Page 1 of 1

Sort by

Explore in 3D

5F2S \| pdb_00005f2s	Download File View File

Crystal structure of human KDM4A in complex with compound 15

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.08 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5TZ, CL, DMS, EDO, ZN

Explore in 3D

5F2W \| pdb_00005f2w	Download File View File

Crystal structure of human KDM4A in complex with compound 16

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5UP, DMS, EDO, ZN

Explore in 3D

5F32 \| pdb_00005f32	Download File View File

Crystal structure of human KDM4A in complex with compound 40

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5V7, DMS, EDO, GOL, ZN

Explore in 3D

5F37 \| pdb_00005f37	Download File View File

Crystal structure of human KDM4A in complex with compound 58

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.22 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	DMS, EDO, N5J, ZN

Explore in 3D

5F39 \| pdb_00005f39	Download File View File

Crystal structure of human KDM4A in complex with compound 37

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5UB, DMS, ZN

Explore in 3D

5F3C \| pdb_00005f3c	Download File View File

Crystal structure of human KDM4A in complex with compound 52d

Le Bihan, Y.-V., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.06 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5U8, CL, DMS, GOL, ZN

Explore in 3D

5F3E \| pdb_00005f3e	Download File View File

Crystal structure of human KDM4A in complex with compound 54a

Le Bihan, Y.-V., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.16 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5UO, DMS, GOL, ZN

Explore in 3D

5F3G \| pdb_00005f3g	Download File View File

Crystal structure of human KDM4A in complex with compound 53a

Le Bihan, Y.-V., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5UL, CL, DMS, ZN

Explore in 3D

5F3I \| pdb_00005f3i	Download File View File

Crystal structure of human KDM4A in complex with compound 54j

Le Bihan, Y.-V., Dempster, S., Westwood, I.M., van Montfort, R.L.M.

(2016) J Med Chem 59: 1388-1409

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.24 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5UJ, CL, DMS, GOL, ZN

Explore in 3D

5F5A \| pdb_00005f5a	Download File View File

Crystal Structure of human JMJD2D complexed with KDOAM16

Krojer, T., Vollmar, M., Crawley, L., Bradley, A.R., Szykowska, A., Ruda, G.F., Yang, H., Burgess-Brown, N., Brennan, P., Bountra, C., Arrowsmith, C.H., Edwards, A., Oppermann, U., von Delft, F., Structural Genomics Consortium (SGC)

(2016) J Med Chem 59: 1388-1409

Released	2015-12-16
Method	X-RAY DIFFRACTION 1.41 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4D (protein)
Unique Ligands	5V0, EDO, NI, SO4, ZN

Explore in 3D

5F5C \| pdb_00005f5c	Download File View File

Crystal Structure of human JMJD2D complexed with KDOPP7

(2016) J Med Chem 59: 1388-1409

Released	2015-12-30
Method	X-RAY DIFFRACTION 1.88 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4D (protein)
Unique Ligands	5V3, EDO, NI, SO4, ZN

Explore in 3D

5F5I \| pdb_00005f5i	Download File View File

Crystal Structure of human JMJD2A complexed with KDOOA011340

Krojer, T., Vollmar, M., Crawley, L., Szykowska, A., Gileadi, C., Johansson, C., England, K., Yang, H., Burgess-Brown, N., Brennan, P., Bountra, C., Arrowsmith, C.H., Edwards, A., Oppermann, U., von Delft, F., Structural Genomics Consortium (SGC)

(2016) J Med Chem 59: 1388-1409

Released	2015-12-30
Method	X-RAY DIFFRACTION 2.63 Å
Organisms	Homo sapiens
Macromolecule	Lysine-specific demethylase 4A (protein)
Unique Ligands	5V1, NI, SO4, ZN

Explore in 3D

5FP3 \| pdb_00005fp3	Download File View File

Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	HUMAN LYSINE-SPECIFIC DEMETHYLASE 6B, JMJD3 (protein)
Unique Ligands	BCN, CO, MG, YC8, ZN

Explore in 3D

5FP4 \| pdb_00005fp4	Download File View File

Crystal structure of human KDM4D in complex with 3-(4- phenylbutanamido)pyridine-4-carboxylic acid

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 4D (protein)
Unique Ligands	FE2, GOL, SO4, YC8, ZN

Explore in 3D

5FP7 \| pdb_00005fp7	Download File View File

Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- yl methylaminopyridine-4-carboxylic acid

Chung, C.

(2016) J Med Chem 59: 1370-1387

Released	2016-11-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 4D (protein)
Unique Ligands	FE2, GOL, SO4, YC8, ZN

Explore in 3D

5FP8 \| pdb_00005fp8	Download File View File

Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- ylmethylaminopyridine-4-carboxylic acid

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 1.98 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 4D (protein)
Unique Ligands	AUY, CO, SO4, ZN

Explore in 3D

5FP9 \| pdb_00005fp9	Download File View File

Crystal structure of human KDM4D in complex with 3-aminopyridine-4- carboxylic acid

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	HUMAN LYSINE-SPECIFIC DEMETHYLASE 4D JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3D, JUMONJI DOMAIN-CONTAINING PROTEIN 2D, JMJD2D (protein)
Unique Ligands	4SV, CO, GOL, SO4, ZN

Explore in 3D

5FPA \| pdb_00005fpa	Download File View File

Crystal structure of human KDM4D in complex with 3H,4H-pyrido-3,4-d- pyrimidin-4-one

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 1.96 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 4D (protein)
Unique Ligands	CO, N5J, SO4, ZN

Explore in 3D

5FPB \| pdb_00005fpb	Download File View File

Crystal structure of human KDM4D in complex with 2-1H-pyrazol-4-yloxy- 3H,4H-pyrido-3,4-d-pyrimidin-4-one

Chung, C.

(2016) J Med Chem 59: 1357

Released	2016-01-27
Method	X-RAY DIFFRACTION 1.91 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 4D (protein)
Unique Ligands	CO, HA6, SO4, ZN

Explore in 3D

5FPL \| pdb_00005fpl	Download File View File

Crystal structure of human JARID1B in complex with CCT363901

Srikannathasan, V., Yann-Vai, L.B., Nowak, R., Johansson, C., Gileadi, C., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Brennan, P., Huber, K., Oppermann, U.

(2016) J Med Chem 59: 1388

Released	2016-01-20
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	LYSINE-SPECIFIC DEMETHYLASE 5B, LYSINE-SPECIFIC DEMETHYLASE 5B (protein)
Unique Ligands	DMS, EDO, MN, QAY, ZN

1 to 20 of 20 Structures

Page 1 of 1

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

5F2S | pdb_00005f2s

Crystal structure of human KDM4A in complex with compound 15

5F2W | pdb_00005f2w

Crystal structure of human KDM4A in complex with compound 16

5F32 | pdb_00005f32

Crystal structure of human KDM4A in complex with compound 40

5F37 | pdb_00005f37

Crystal structure of human KDM4A in complex with compound 58

5F39 | pdb_00005f39

Crystal structure of human KDM4A in complex with compound 37

5F3C | pdb_00005f3c

Crystal structure of human KDM4A in complex with compound 52d

5F3E | pdb_00005f3e

Crystal structure of human KDM4A in complex with compound 54a

5F3G | pdb_00005f3g

Crystal structure of human KDM4A in complex with compound 53a

5F3I | pdb_00005f3i

Crystal structure of human KDM4A in complex with compound 54j

5F5A | pdb_00005f5a

Crystal Structure of human JMJD2D complexed with KDOAM16

5F5C | pdb_00005f5c

Crystal Structure of human JMJD2D complexed with KDOPP7

5F5I | pdb_00005f5i

Crystal Structure of human JMJD2A complexed with KDOOA011340

5FP3 | pdb_00005fp3

Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases

5FP4 | pdb_00005fp4

Crystal structure of human KDM4D in complex with 3-(4- phenylbutanamido)pyridine-4-carboxylic acid

5FP7 | pdb_00005fp7

Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- yl methylaminopyridine-4-carboxylic acid

5FP8 | pdb_00005fp8

Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- ylmethylaminopyridine-4-carboxylic acid

5FP9 | pdb_00005fp9

Crystal structure of human KDM4D in complex with 3-aminopyridine-4- carboxylic acid

5FPA | pdb_00005fpa

Crystal structure of human KDM4D in complex with 3H,4H-pyrido-3,4-d- pyrimidin-4-one

5FPB | pdb_00005fpb

Crystal structure of human KDM4D in complex with 2-1H-pyrazol-4-yloxy- 3H,4H-pyrido-3,4-d-pyrimidin-4-one

5FPL | pdb_00005fpl

Crystal structure of human JARID1B in complex with CCT363901

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

5F2S | pdb_00005f2s

5F2W | pdb_00005f2w

5F32 | pdb_00005f32

5F37 | pdb_00005f37

5F39 | pdb_00005f39

5F3C | pdb_00005f3c

5F3E | pdb_00005f3e

5F3G | pdb_00005f3g

5F3I | pdb_00005f3i

5F5A | pdb_00005f5a

5F5C | pdb_00005f5c

5F5I | pdb_00005f5i

5FP3 | pdb_00005fp3

5FP4 | pdb_00005fp4

5FP7 | pdb_00005fp7

5FP8 | pdb_00005fp8

5FP9 | pdb_00005fp9

5FPA | pdb_00005fpa

5FPB | pdb_00005fpb

5FPL | pdb_00005fpl