RCSB PDB: Search

2M8M \| pdb_00002m8m	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Serrano, S., Huarte, N., Nieva, J.L., Jimenez, M.

(2014) J Biological Chem 289: 6565-6580

Released	2014-01-22
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus type 1 (SC ISOLATE)
Macromolecule	Transmembrane protein gp41 (protein)

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2M8O \| pdb_00002m8o	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in DPC

Serrano, S., Huarte, N., Nieva, J.L., Jimenez, M.

(2014) J Biological Chem 289: 6565-6580

Released	2014-01-22
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus type 1 (SC ISOLATE)
Macromolecule	Transmembrane protein gp41 (protein)

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2MG1 \| pdb_00002mg1	Download File View File

NMR assignment and structure of a peptide derived from the trans-membrane region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Serrano, S., Apellaniz, B., Huarte, N.L., Nieva, J.L., Jimenez, M.A.

(2015) J Biological Chem 290: 12999-13015

Released	2015-03-25
Method	SOLUTION NMR
Organisms	HIV-1 M:B_HXB2R
Macromolecule	Transmembrane protein gp41 (protein)

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2MG2 \| pdb_00002mg2	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Serrano, S., Apellaniz, B., Huarte, N.L., Nieva, J.L., Jimenez, M.A.

(2015) J Biological Chem 290: 12999-13015

Released	2015-03-25
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	Transmembrane protein gp41 (protein)

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2MG3 \| pdb_00002mg3	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of dodecylphosphocholine micelles

Serrano, S., Apellaniz, B., Huarte, N., Nieva, J.L., Jimenez, M.A.

(2015) J Biological Chem 290: 12999-13015

Released	2015-03-25
Method	SOLUTION NMR
Organisms	HIV-1 M:B_HXB2R
Macromolecule	Envelope glycoprotein gp41 (protein)

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2NCS \| pdb_00002ncs	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of dodecylphosphocholine micelles

Jimenez, M., Nieva, J.L., Rujas, E., Partida-Hanon, A., Bruix, M.

(2016) Sci Rep 6: 38177-38177

Released	2017-02-22
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	Envelope glycoprotein gp41 (protein)

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2NCT \| pdb_00002nct	Download File View File

NMR assignment and structure of a peptide derived from the membrane proximal external region of HIV-1 gp41 in the presence of hexafluoroisopropanol

Jimenez, M., Nieva, J.L., Rujas, E., Partida-Hanon, A., Bruix, M.

(2016) Sci Rep 6: 38177-38177

Released	2017-02-22
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	Envelope glycoprotein gp41 (protein)

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4WY7 \| pdb_00004wy7	Download File View File

Crystal structure of recombinant 4E10 expressed in Escherichia coli with epitope bound

Rujas, E., Morante, K., Tsumoto, K., Nieva, J.L., Caaveiro, J.M.M.

(2015) J Biological Chem 290: 12999-13015

Released	2015-03-25
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens Human immunodeficiency virus type 1 (WMJ2 ISOLATE)
Macromolecule	Envelope glycoprotein gp160 (protein) Fab 4E10 Heavy chain (protein) Fab 4E10Light chain (protein)
Unique Ligands	GOL

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5CIL \| pdb_00005cil	Download File View File

Crystal Structure of non-neutralizing version of 4E10 (WDWD) with epitope bound

Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K.

(2015) J Virol 89: 11975-11989

Released	2015-09-23
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	FAB 4E10 HEAVY CHAIN (protein) FAB 4E10 LIGHT CHAIN (protein) Peptide from the MPER region of the ENV protein of HIV-1 (protein)
Unique Ligands	ACT, CL, GOL

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5CIN \| pdb_00005cin	Download File View File

Crystal Structure of non-neutralizing version of 4E10 (DeltaLoop) with epitope bound

Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K.

(2015) J Virol 89: 11975-11989

Released	2015-09-23
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	FAB 4E10 HEAVY CHAIN (protein) FAB 4E10 LIGHT CHAIN (protein) Peptide from MPER region of HIV-1 ENV (protein)
Unique Ligands	CL, GOL

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5CIP \| pdb_00005cip	Download File View File

Crystal Structure of Unbound 4E10

Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K.

(2015) J Virol 89: 11975-11989

Released	2015-09-23
Method	X-RAY DIFFRACTION 2.48 Å
Organisms	Homo sapiens
Macromolecule	FAB 4E10 HEAVY CHAIN (protein) FAB 4E10 LIGHT CHAIN (protein)

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5GHW \| pdb_00005ghw	Download File View File

Crystal structure of broad neutralizing antibody 10E8 with long epitope bound

Caaveiro, J.M.M., Rujas, E., Morante, K., Nieva, J.L., Tsumoto, K.

(2016) Sci Rep 6: 38177-38177

Released	2016-11-23
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Endogenous retrovirus group K member 8 Env polyprotein (protein) FAB 10E8 HEAVY CHAIN (protein) FAB 10E8 LIGHT CHAIN (protein)
Unique Ligands	PO4

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5NVP \| pdb_00005nvp	Download File View File

NMR assignment and structure of a peptide derived from the fusion peptide of HIV-1 gp41 in the presence of dodecylphosphocholine micelles

Jimenez, M.A., Serrano, S., Nieva, J.L., Huarte, N.

(2017) Biochemistry 56: 5503-5511

Released	2017-12-06
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	Envelope glycoprotein,Gp41 (protein)

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5NWU \| pdb_00005nwu	Download File View File

NMR assignment and structure of a peptide derived from the fusion peptide of HIV-1 gp41 in the presence of hexafluoroisopropanol

Jimenez, M.A., Serrano, S., Nieva, J.L., Huarte, N.

(2017) Biochemistry 56: 5503-5511

Released	2017-12-06
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	wtFP-tag,Gp41 (protein)

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5NWV \| pdb_00005nwv	Download File View File

NMR assignment and structure of a peptide derived from the fusion peptide of HIV-1 gp41 in the presence of dodecylphosphocholine micelles

Jimenez, M.A., Serrano, S., Nieva, J.L., Huarte, N.

(2017) Biochemistry 56: 5503-5511

Released	2017-12-06
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	scrFP-tag,Gp41 (protein)

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5NWW \| pdb_00005nww	Download File View File

NMR assignment and structure of a peptide derived from the fusion peptide of HIV-1 gp41 in the presence of dodecylphosphocholine micelles

Jimenez, M.A., Serrano, S., Nieva, J.L., Huarte, N.

(2017) Biochemistry 56: 5503-5511

Released	2017-12-06
Method	SOLUTION NMR
Organisms	Human immunodeficiency virus 1
Macromolecule	scrFP-tag,Gp41 (protein)

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5X08 \| pdb_00005x08	Download File View File

Crystal structure of broadly neutralizing anti-HIV-1 antibody 4E10, mutant Npro, with peptide bound

Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K.

(2017) J Mol Biology 429: 1213-1226

Released	2017-04-05
Method	X-RAY DIFFRACTION 1.49 Å
Organisms	Homo sapiens Human immunodeficiency virus type 1 (MAL ISOLATE)
Macromolecule	Envelope glycoprotein gp160 (protein) Fab 4E10 Heavy chain (protein) Fab 4E10 Light chain (protein)
Unique Ligands	ACT, CL, GOL, P6G, PGE

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6X4G \| pdb_00006x4g	Download File View File

Crystal structure of ICOS in complex with ICOS-L and an anti ICOS-L VNAR domain

Rujas, E., Sicard, T., Julien, J.P.

(2020) Nat Commun 11: 5066-5066

Released	2020-10-14
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens Orectolobus maculatus
Macromolecule	ICOS ligand (protein) Inducible T-cell costimulator (protein) anti ICOS-L VHH domain VNAR (protein)
Unique Ligands	GOL, NAG
Unique branched monosaccharides	BMA, MAN, NAG

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6X4T \| pdb_00006x4t	Download File View File

Crystal structure of ICOS-L in complex with Prezalumab and VNAR domain

Rujas, E., Sicard, T., Julien, J.P.

(2020) Nat Commun 11: 5066-5066

Released	2020-10-14
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Homo sapiens Orectolobus maculatus
Macromolecule	ICOS ligand (protein) Prezalumab Fab Heavy chain (protein) Prezalumab Fab Light chain (protein) VNAR (protein)
Unique Ligands	GOL, NAG
Unique branched monosaccharides	NAG

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7EKB \| pdb_00007ekb	Download File View File

Crystal structure of 4E10 modified with pyrene acetamide

Caaveiro, J.M.M., Rujas, E., Nieva, J.L.

(2021) iScience 24: 102987-102987

Released	2021-08-11
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10 (protein) Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10 (protein) MPER region of the HIV-1 envelope glycoprotein protein gp41 (protein)
Unique Ligands	ACT, GOL

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7EKK \| pdb_00007ekk	Download File View File

Anti-HIV-1 broadly neutralizing antibody delta-loop 4E10 modified with pyrene acetamide

Caaveiro, J.M.M., Rujas, E., Nieva, J.L.

(2021) iScience 24: 102987-102987

Released	2021-08-11
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Heavy chain of the Fab region of Delta-loop variant of anti-HIV-1 broadly neutralizing antibody 4E10 modified with pyrene acetamide (protein) Light chain of the Fab region of Delta-loop variant of anti-HIV-1 broadly neutralizing antibody 4E10 modified with pyrene acetamide (protein) MPER region of the envelope glycoprotein gp41 from HIV-1 (protein)
Unique Ligands	CL, GOL, NH4, SO4

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7JOO \| pdb_00007joo	Download File View File

Crystal structure of ICOS in complex with antibody STIM003 and anti-kappa VHH domain

Rujas, E., Sicard, T., Julien, J.P.

(2020) Nat Commun 11: 5066-5066

Released	2020-10-14
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens Lama glama
Macromolecule	Inducible T-cell costimulator (protein) STIM003 Fab Heavy chain (protein) STIM003 Fab Light chain (protein) anti-kappa VHH (protein)
Unique Ligands	GOL, NAG

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7K9Z \| pdb_00007k9z	Download File View File

Crystal structure of SARS-CoV-2 receptor binding domain in complex with the Fab fragments of neutralizing antibodies 298 and 52

Newton, J.C., Kucharska, I., Rujas, E., Cui, H., Julien, J.P.

(2021) Nat Commun 12: 3661-3661

Released	2020-10-28
Method	X-RAY DIFFRACTION 2.95 Å
Organisms	Homo sapiens Severe acute respiratory syndrome coronavirus 2
Macromolecule	298 Fab Heavy Chain (protein) 298 Fab Light Chain (protein) 52 Fab Heavy Chain (protein) 52 Fab Light Chain (protein) Spike protein S1 (protein)
Unique Ligands	NAG