RCSB PDB: Search

1T2A \| pdb_00001t2a	Download File View File

Crystal structure of human GDP-D-mannose 4,6-dehydratase

Walker, J.R., Vedadi, M., Sharma, S., Houston, S., Wasney, G., Loppnau, P., Sundstrom, M., Arrowsmith, C., Edwards, A., Oppermann, U.

To be published

Released	2004-05-10
Method	X-RAY DIFFRACTION 1.84 Å
Organisms	Homo sapiens
Macromolecule	GDP-mannose 4,6 dehydratase (protein)
Unique Ligands	GDP, NDP

Explore in 3D

1XG5 \| pdb_00001xg5	Download File View File

Structure of human putative dehydrogenase MGC4172 in complex with NADP

Kavanagh, K., Ng, S., Sharma, S., Vedadi, M., von Delft, F., Walker, J.R., dhe Paganon, S., Bray, J., Oppermann, U., Edwards, A., Arrowsmith, C., Sundstrom, M., Structural Genomics Consortium (SGC)

To be published

Released	2004-10-05
Method	X-RAY DIFFRACTION 1.53 Å
Organisms	Homo sapiens
Macromolecule	ARPG836 (protein)
Unique Ligands	ACY, NAP

Explore in 3D

1XSE \| pdb_00001xse	Download File View File

Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1

Ogg, D., Elleby, B., Norstrom, C., Stefansson, K., Abrahmsen, L., Oppermann, U., Svensson, S.

(2005) J Biological Chem 280: 3789-3794

Released	2004-11-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Cavia porcellus
Macromolecule	11beta-hydroxysteroid dehydrogenase type 1 (protein)
Unique Ligands	NDP

Explore in 3D

1YB1 \| pdb_00001yb1	Download File View File

Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI

Lukacik, P., Bunkoczi, G., Kavanagh, K., Ng, S., von Delft, F., Bray, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2004-12-28
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	17-beta-hydroxysteroid dehydrogenase type XI (protein)
Unique Ligands	AOI, CL, GOL, SO4

Explore in 3D

1YB5 \| pdb_00001yb5	Download File View File

Crystal structure of human Zeta-Crystallin with bound NADP

Debreczeni, J., Berridge, G., Kavanagh, K., Colbrook, S., Bray, J., Williams, L., Oppermann, U., Sundstrom, M., Arrowsmith, C., Edwards, A., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)

To be published

Released	2004-12-28
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	Quinone oxidoreductase (protein)
Unique Ligands	ACT, CL, GOL, NAP

Explore in 3D

1YDE \| pdb_00001yde	Download File View File

Crystal Structure of Human Retinal Short-Chain Dehydrogenase/Reductase 3

Lukacik, P., Bunkozci, G., Kavanagh, K., Sundstrom, M., Arrowsmith, C., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

(2007) Biochem J 402: 419-427

Released	2005-01-18
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Retinal dehydrogenase/reductase 3 (protein)

Explore in 3D

1YQ7 \| pdb_00001yq7	Download File View File

Human farnesyl diphosphate synthase complexed with risedronate

Kavanagh, K.L., Guo, K., Von delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-02-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Farnesyl pyrophosphate synthetase (protein)
Unique Ligands	MG, PO4, RIS

Explore in 3D

1YV5 \| pdb_00001yv5	Download File View File

Human farnesyl diphosphate synthase complexed with Mg and risedronate

Kavanagh, K.L., Guo, K., Von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)

(2006) Proc Natl Acad Sci U S A 103: 7829-7834

Released	2005-03-01
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	Farnesyl pyrophosphate synthetase (protein)
Unique Ligands	MG, PO4, RIS

Explore in 3D

1YXM \| pdb_00001yxm	Download File View File

Crystal structure of peroxisomal trans 2-enoyl CoA reductase

Jansson, A., Ng, S., Arrowsmith, C., Sharma, S., Edwards, A.M., Von Delft, F., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-03-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	peroxisomal trans 2-enoyl CoA reductase (protein)
Unique Ligands	ADE, PO4, SO4

Explore in 3D

1Z6Z \| pdb_00001z6z	Download File View File

Crystal Structure of Human Sepiapterin Reductase in complex with NADP+

Ugochukwu, E., Kavanagh, K., Ng, S., Arrowsmith, C., Edwards, A., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-04-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Sepiapterin reductase (protein)
Unique Ligands	CL, NAP, SO4

Explore in 3D

1ZBQ \| pdb_00001zbq	Download File View File

Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD

Lukacik, P., Shafqat, N., Kavanagh, K., Bray, J., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-04-26
Method	X-RAY DIFFRACTION 2.19 Å
Organisms	Homo sapiens
Macromolecule	17-beta-hydroxysteroid dehydrogenase 4 (protein)
Unique Ligands	NAD

Explore in 3D

1ZSV \| pdb_00001zsv	Download File View File

Crystal structure of human NADP-dependent leukotriene B4 12-hydroxydehydrogenase

Turnbull, A.P., Johansson, C., Savitsky, P., Guo, K., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-06-21
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	NADP-dependent leukotriene B4 12-hydroxydehydrogenase (protein)
Unique Ligands	CL

Explore in 3D

1ZSX \| pdb_00001zsx	Download File View File

Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)

Wennerstrand, P., Johannsson, I., Ugochukwu, E., Kavanagh, K., Edwards, A., Arrowsmith, C., Williams, L., Sundstrom, M., Guo, K., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-06-07
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	Voltage-gated potassium channel beta-2 subunit (protein)
Unique Ligands	CL, NAP

Explore in 3D

1ZSY \| pdb_00001zsy	Download File View File

The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63)

Lukacik, P., Shafqat, N., Kavanagh, K.L., Johansson, C., Smee, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-06-07
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Homo sapiens
Macromolecule	MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE (protein)
Unique Ligands	GOL, SO4

Explore in 3D

1ZW5 \| pdb_00001zw5	Download File View File

X-ray structure of Farnesyl diphosphate synthase protein

Kavanagh, K.L., Guo, K., Wu, X., von Delft, F., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)

(2006) Proc Natl Acad Sci U S A 103: 7829-7834

Released	2005-06-28
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	farnesyl diphosphate synthase (protein)
Unique Ligands	IPE, MG, ZOL

Explore in 3D

1ZX1 \| pdb_00001zx1	Download File View File

Human quinone oxidoreductase 2 (NQO2) in complex with the cytostatic prodrug CB1954

Jansson, A., Wu, X., Kavanagh, K., Kerr, D., Knox, R., Walton, R., Gunther, U., Ludwig, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-06-14
Method	X-RAY DIFFRACTION 2.16 Å
Organisms	Homo sapiens
Macromolecule	NRH dehydrogenase [quinone] 2 (protein)
Unique Ligands	CB1, FAD, ZN

Explore in 3D

2A1X \| pdb_00002a1x	Download File View File

Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate

Kavanagh, K.L., McDonough, M.A., Searles, T., Butler, D., Bunkoczi, G., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Schofield, C.J., Oppermann, U., Structural Genomics Consortium (SGC)

(2005) J Biological Chem 280: 41101-41110

Released	2005-08-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Phytanoyl-CoA dioxygenase (protein)
Unique Ligands	AKG, FE2

Explore in 3D

2AG5 \| pdb_00002ag5	Download File View File

Crystal Structure of Human DHRS6

Kunde, G., Lukacik, P., Papagrigoriou, E., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

(2006) J Biological Chem 281: 10291-10297

Released	2005-08-09
Method	X-RAY DIFFRACTION 1.84 Å
Organisms	Homo sapiens
Macromolecule	dehydrogenase/reductase (SDR family) member 6 (protein)
Unique Ligands	NAD, SO4

Explore in 3D

2AW5 \| pdb_00002aw5	Download File View File

Crystal structure of a human malic enzyme

Papagrigoriou, E., Berridge, G., Smee, C., Bray, J., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Gileadi, O., von Delft, F., Structural Genomics Consortium (SGC)

To be published

Released	2005-09-20
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	NADP-dependent malic enzyme (protein)

Explore in 3D

2B69 \| pdb_00002b69	Download File View File

Crystal Structure of Human UDP-glucoronic acid decarboxylase

Ugochukwu, E., Dubinina, E., Kavanagh, K., Sundstrom, M., Weigelt, J., Edwards, A., Arrowsmith, C., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)

To be published

Released	2005-10-18
Method	X-RAY DIFFRACTION 1.21 Å
Organisms	Homo sapiens
Macromolecule	UDP-glucuronate decarboxylase 1 (protein)
Unique Ligands	NAD, UDP

Explore in 3D

2BEL \| pdb_00002bel	Download File View File

Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone

Kavanagh, K., Wu, X., Svensson, S., Elleby, B., von Delft, F., Debreczeni, J.E., Sharma, S., Bray, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Abrahmsen, L., Oppermann, U.

To be published

Released	2004-12-06
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1 (protein)
Unique Ligands	CBO, CL, NAP

Explore in 3D

2BLE \| pdb_00002ble	Download File View File

Structure of human guanosine monophosphate reductase GMPR1 in complex with GMP

Bunkoczi, G., Haroniti, A., Ng, S., von Delft, F., Oppermann, U., Arrowsmith, C., Sundstrom, M., Edwards, A., Gileadi, O.

To be published

Released	2005-03-09
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	GMP REDUCTASE I (protein)
Unique Ligands	5GP, NA

Explore in 3D

2BP1 \| pdb_00002bp1	Download File View File

Structure of the aflatoxin aldehyde reductase in complex with NADPH

Debreczeni, J.E., Lukacik, P., Kavanagh, K., Dubinina, E., Bray, J., Colebrook, S., Haroniti, A., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Gileadi, O., Oppermann, U.

To be published

Released	2005-05-11
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2 (protein)
Unique Ligands	FLC, NDP