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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Machner, M.P."

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Search Summary

This query matches 16 Structures.

Refinements

Structure Determination Methodology

experimental (16)

Scientific Name of Source Organism

	Homo sapiens (7)
	Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (7)
	Legionella pneumophila (4)
	Listeria monocytogenes EGD-e (3)
	Legionella pneumophila subsp. pneumophila ATCC 43290 (2)

Taxonomy

	Bacteria (16)
	Eukaryota (7)

Experimental Method

X-RAY DIFFRACTION (16)

Polymer Entity Type

Protein (16)

Refinement Resolution (Å)

	1.5 - 2.0 (8)
	2.5 - 3.0 (4)
	3.0 - 3.5 (2)
	3.5 - 4.0 (1)
	4.0 - 4.5 (1)

Release Date

	2000 - 2004 (3)
	2010 - 2014 (5)
	2015 - 2019 (6)
	2020 - 2024 (2)

Enzyme Classification Name

	Hydrolases (6)
	Transferases (4)
	Ligases (1)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (14)
	Cyclic (2)

SCOP Classification

	Alpha and beta proteins (a/b) (5)
	Artifacts (5)
	All beta proteins (3)
	All alpha proteins (2)
	Alpha and beta proteins (a+b) (1)

AllSelected

1 to 16 of 16 Structures

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1O6S \| pdb_00001o6s	Download File View File

Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex

Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M.P., Domann, E., Wehland, J., Chakraborty, T., Heinz, D.W.

(2002) Cell 111: 825

Released	2002-12-13
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Listeria monocytogenes EGD-e
Macromolecule	E-CADHERIN (protein) INTERNALIN A (protein)
Unique Ligands	CA, CL

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1O6T \| pdb_00001o6t	Download File View File

Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed

Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M.P., Domann, E., Wehland, J., Chakraborty, T., Heinz, D.W.

(2002) Cell 111: 825

Released	2002-12-23
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Listeria monocytogenes EGD-e
Macromolecule	INTERNALIN A (protein)
Unique Ligands	CA, CL, MES, MG, SO4

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1O6V \| pdb_00001o6v	Download File View File

Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed

Schubert, W.-D., Urbanke, C., Ziehm, T., Beier, V., Machner, M.P., Domann, E., Wehland, J., Chakraborty, T., Heinz, D.W.

(2002) Cell 111: 825

Released	2002-12-23
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Listeria monocytogenes EGD-e
Macromolecule	INTERNALIN A (protein)
Unique Ligands	CA

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3JZ9 \| pdb_00003jz9	Download File View File

Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila

Schoebel, S., Oesterlin, L.K., Blankenfeldt, W., Goody, R.S., Itzen, A.

(2009) Mol Cell 36: 1060-1072

Released	2010-01-19
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	Uncharacterized protein DrrA (protein)

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3JZA \| pdb_00003jza	Download File View File

Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila

Schoebel, S., Oesterlin, L.K., Blankenfeldt, W., Goody, R.S., Itzen, A.

(2009) Mol Cell 36: 1060-1072

Released	2010-01-19
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	Ras-related protein Rab-1B (protein) Uncharacterized protein DrrA (protein)
Unique Ligands	PO4

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4IIK \| pdb_00004iik	Download File View File

Legionella pneumophila effector

Tascon, I., Chen, Y., Neunuebel, M.R., Rojas, A.L., Machner, M.P., Hierro, A.

(2013) PLoS Pathog 9: e1003382-e1003382

Released	2013-06-19
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	Adenosine monophosphate-protein hydrolase SidD (protein)
Unique Ligands	CL, GOL, MG

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4IIP \| pdb_00004iip	Download File View File

Legionella pneumophila effector

Tascon, I., Chen, Y., Neunuebel, M.R., Rojas, A.L., Machner, M.P., Hierro, A.

(2013) PLoS Pathog 9: e1003382-e1003382

Released	2013-06-19
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	Adenosine monophosphate-protein hydrolase SidD (protein)
Unique Ligands	CL, GOL

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4KYI \| pdb_00004kyi	Download File View File

Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5

Lucas, M., Gaspar, A.H., Pallara, C., Rojas, A.L., Fernandez-Recio, J., Machner, M.P., Hierro, A.

(2014) Proc Natl Acad Sci U S A 111: E3514-E3523

Released	2014-08-13
Method	X-RAY DIFFRACTION 3.075 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	Ras-related protein Rab-5C (protein) VipD (protein)
Unique Ligands	EDO, GNP, GOL, MG

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5MIY \| pdb_00005miy	Download File View File

Crystal structure of the E3 ubiquitin ligase RavN from Legionella pneumophila

Lucas, M., Abascal-Palacios, G., Rojas, A.L., Hierro, A.

(2018) PLoS Pathog 14: e1006897-e1006897

Released	2018-05-23
Method	X-RAY DIFFRACTION 1.717 Å
Organisms	Legionella pneumophila
Macromolecule	E3 ubiquitin ligase RavN (protein)
Unique Ligands	EDO, NA, SO4

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5OSH \| pdb_00005osh	Download File View File

Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236)

Romano-Moreno, M., Rojas, A.L., Lucas, M., Isupov, M.N., Hierro, A.

(2017) Proc Natl Acad Sci U S A 114: E11151-E11160

Released	2017-12-13
Method	X-RAY DIFFRACTION 4.3 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila ATCC 43290
Macromolecule	Interaptin (protein) Vacuolar protein sorting-associated protein 29 (protein) Vacuolar protein sorting-associated protein 35 (protein)

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5OSI \| pdb_00005osi	Download File View File

Structure of retromer VPS29-VPS35C subunits complexed with RidL harpin loop (163-176)

Romano-Moreno, M., Rojas, A.L., Lucas, M., Isupov, M.N., Hierro, A.

(2017) Proc Natl Acad Sci U S A 114: E11151-E11160

Released	2017-12-13
Method	X-RAY DIFFRACTION 2.52 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila ATCC 43290
Macromolecule	Interaptin (protein) Vacuolar protein sorting-associated protein 29 (protein) Vacuolar protein sorting-associated protein 35 (protein)
Unique Ligands	EDO, NA

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5OT4 \| pdb_00005ot4	Download File View File

Structure of the Legionella pneumophila effector RidL (1-866)

Romano-Moreno, M., Rojas, A.L., Lucas, M., Isupov, M.N., Hierro, A.

(2017) Proc Natl Acad Sci U S A 114: E11151-E11160

Released	2017-12-13
Method	X-RAY DIFFRACTION 3 Å
Organisms	Legionella pneumophila
Macromolecule	Interaptin (protein)
Unique Ligands	GOL

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6MCP \| pdb_00006mcp	Download File View File

L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A

Beyrakhova, K.A., Xu, C., Boniecki, M.T., Cygler, M.

(2020) Proc Natl Acad Sci U S A 117: 14433-14443

Released	2019-09-04
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	LegK7 (protein) MOB kinase activator 1A (protein)
Unique Ligands	ANP, MN, P6G, PEG, PG4, ZN

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6MCQ \| pdb_00006mcq	Download File View File

L. pneumophila effector kinase LegK7 in complex with human MOB1A

Beyrakhova, K.A., Xu, C., Boniecki, M.T., Cygler, M.

(2020) Proc Natl Acad Sci U S A 117: 14433-14443

Released	2019-09-04
Method	X-RAY DIFFRACTION 2.57 Å
Organisms	Homo sapiens Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Macromolecule	LegK7 (protein) MOB kinase activator 1A (protein)
Unique Ligands	P6G, PEG, PG4, ZN

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6RP4 \| pdb_00006rp4	Download File View File

CDT of SidD, deAMPylase from Legionella pneumophila

Tascon, I., Lucas, M., Rojas, A.L., Hierro, A.

(2020) PLoS Pathog 16: e1008734-e1008734

Released	2020-10-07
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Legionella pneumophila
Macromolecule	Adenosine monophosphate-protein hydrolase SidD (protein)
Unique Ligands	GOL, MG, NA, ZN

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6RRE \| pdb_00006rre	Download File View File

SidD, deAMPylase from Legionella pneumophila

Tascon, I., Lucas, M., Rojas, A.L., Hierro, A.

(2020) PLoS Pathog 16: e1008734-e1008734

Released	2020-10-07
Method	X-RAY DIFFRACTION 3.586 Å
Organisms	Legionella pneumophila
Macromolecule	Adenosine monophosphate-protein hydrolase SidD (protein)
Unique Ligands	MG

1 to 16 of 16 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1O6S | pdb_00001o6s

Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex

1O6T | pdb_00001o6t

Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed

1O6V | pdb_00001o6v

Internalin (INLA, Listeria monocytogenes) - functional domain, uncomplexed

3JZ9 | pdb_00003jz9

Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila

3JZA | pdb_00003jza

Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila

4IIK | pdb_00004iik

Legionella pneumophila effector

4IIP | pdb_00004iip

Legionella pneumophila effector

4KYI | pdb_00004kyi

Crystal structure of the phospholipase VipD from Legionella pneumophila in complex with the human GTPase Rab5

5MIY | pdb_00005miy

Crystal structure of the E3 ubiquitin ligase RavN from Legionella pneumophila

5OSH | pdb_00005osh

Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236)

5OSI | pdb_00005osi

Structure of retromer VPS29-VPS35C subunits complexed with RidL harpin loop (163-176)

5OT4 | pdb_00005ot4

Structure of the Legionella pneumophila effector RidL (1-866)

6MCP | pdb_00006mcp

L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A

6MCQ | pdb_00006mcq

L. pneumophila effector kinase LegK7 in complex with human MOB1A

6RP4 | pdb_00006rp4

CDT of SidD, deAMPylase from Legionella pneumophila

6RRE | pdb_00006rre

SidD, deAMPylase from Legionella pneumophila

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1O6S | pdb_00001o6s

1O6T | pdb_00001o6t

1O6V | pdb_00001o6v

3JZ9 | pdb_00003jz9

3JZA | pdb_00003jza

4IIK | pdb_00004iik

4IIP | pdb_00004iip

4KYI | pdb_00004kyi

5MIY | pdb_00005miy

5OSH | pdb_00005osh

5OSI | pdb_00005osi

5OT4 | pdb_00005ot4

6MCP | pdb_00006mcp

6MCQ | pdb_00006mcq

6RP4 | pdb_00006rp4

6RRE | pdb_00006rre