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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Eck, M.J."

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Search Summary

This query matches 213 Structures.

Refinements

Structure Determination Methodology

experimental (213)

Scientific Name of Source Organism

	Homo sapiens (169)
	Gallus gallus (16)
	Saccharomyces cerevisiae (14)
	Mus musculus (10)
	Spodoptera exigua (5)
	Escherichia coli H489 (2)
	Escherichia coli O157:H7 (2)
	Oryctolagus cuniculus (2)
	Drosophila melanogaster (1)
	Hamster polyomavirus (1)

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Taxonomy

	Eukaryota (209)
	Eukaryota (eukaryotes) (8)
	Bacteria (5)
	Archaea (1)
	Monodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (200)
	SOLUTION NMR (7)
	ELECTRON MICROSCOPY (6)

Polymer Entity Type

Protein (213)

Refinement Resolution (Å)

	1.0 - 1.5 (4)
	1.5 - 2.0 (28)
	2.0 - 2.5 (63)
	2.5 - 3.0 (59)
	3.0 - 3.5 (40)
	3.5 - 4.0 (6)
	4.0 - 4.5 (3)
	> 4.5 (3)

Release Date

	1990 - 1994 (2)
	1995 - 1999 (19)
	2000 - 2004 (22)
	2005 - 2009 (41)
	2010 - 2014 (29)
	2015 - 2019 (34)
	2020 - 2024 (66)

Enzyme Classification Name

	Transferases (164)
	Hydrolases (12)
	Lyases (1)

Membrane Protein Annotation

OPM (2)

Symmetry Type

	Asymmetric (160)
	Cyclic (61)
	Dihedral (1)
	Helical (1)

SCOP Classification

	Alpha and beta proteins (a+b) (97)
	All beta proteins (30)
	All alpha proteins (13)
	Artifacts (14)
	Small proteins (5)
	Peptides (6)
	Alpha and beta proteins (a/b) (4)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 213 Structures

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1B47 \| pdb_00001b47	Download File View File

STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70

Meng, W., Sawasdikosol, S., Burakoff, S.J., Eck, M.J.

(1999) Nature 398: 84-90

Released	1999-04-27
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	CBL (protein)
Unique Ligands	CA

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1D1Z \| pdb_00001d1z	Download File View File

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP

Poy, F., Yaffe, M.B., Sayos, J., Saxena, K., Eck, M.J.

(1999) Mol Cell 4: 555-561

Released	1999-10-13
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	SAP SH2 DOMAIN (protein)
Unique Ligands	SO4

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1D4T \| pdb_00001d4t	Download File View File

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH A SLAM PEPTIDE

Poy, F., Yaffe, M.B., Sayos, J., Saxena, K., Eck, M.J.

(1999) Mol Cell 4: 555-561

Released	1999-10-14
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Homo sapiens
Macromolecule	SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE (protein) T CELL SIGNAL TRANSDUCTION MOLECULE SAP (protein)

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1D4W \| pdb_00001d4w	Download File View File

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

Poy, F., Yaffe, M.B., Sayos, J., Saxena, K., Eck, M.J.

(1999) Mol Cell 4: 555-561

Released	1999-10-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE (protein) T CELL SIGNAL TRANSDUCTION MOLECULE SAP (protein)

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1EG3 \| pdb_00001eg3	Download File View File

STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE

Huang, X., Poy, F., Zhang, R., Joachimiak, A., Sudol, M., Eck, M.J.

(2000) Nat Struct Biol 7: 634-638

Released	2000-08-23
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	DYSTROPHIN (protein)

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1EG4 \| pdb_00001eg4	Download File View File

STRUCTURE OF A DYSTROPHIN WW DOMAIN FRAGMENT IN COMPLEX WITH A BETA-DYSTROGLYCAN PEPTIDE

Huang, X., Poy, F., Zhang, R., Joachimiak, A., Sudol, M., Eck, M.J.

(2000) Nat Struct Biol 7: 634-638

Released	2000-08-23
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	BETA-DYSTROGLYCAN (protein) DYSTROPHIN (protein)

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1EXT \| pdb_00001ext	Download File View File

EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.

Naismith, J.H., Sprang, S.R.

(1996) Structure 4: 1251-1262

Released	1997-01-11
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	TUMOR NECROSIS FACTOR RECEPTOR (protein)
Unique Ligands	MG, SO4

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1F3M \| pdb_00001f3m	Download File View File

CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE PAK1

Lei, M., Lu, W., Meng, W., Parrini, M.-C., Eck, M.J., Mayer, B.J., Harrison, S.C.

(2000) Cell 102: 387-397

Released	2000-06-29
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN KINASE PAK-ALPHA (protein)
Unique Ligands	IOD

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1FMK \| pdb_00001fmk	Download File View File

CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC

Xu, W., Harrison, S.C., Eck, M.J.

(1997) Nature 385: 595-602

Released	1997-08-20
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	TYROSINE-PROTEIN KINASE SRC (protein)

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1HCS \| pdb_00001hcs	Download File View File

NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX

Gampe Junior, R.T., Xu, R.X.

(1995) Biochemistry 34: 2107-2121

Released	1995-09-15
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	ACETYL-PYEEIE-OH (protein) HUMAN SRC (protein)

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1HCT \| pdb_00001hct	Download File View File

NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX

Gampe Junior, R.T., Xu, R.X.

(1995) Biochemistry 34: 2107-2121

Released	1995-09-15
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	ACETYL-PYEEIE-OH (protein) HUMAN SRC (protein)

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1I1Q \| pdb_00001i1q	Download File View File

STRUCTURE OF THE COOPERATIVE ALLOSTERIC ANTHRANILATE SYNTHASE FROM SALMONELLA TYPHIMURIUM

Morollo, A.A., Eck, M.J.

(2001) Nat Struct Biol 8: 243-247

Released	2001-04-18
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium
Macromolecule	ANTHRANILATE SYNTHASE COMPONENT I (protein) ANTHRANILATE SYNTHASE COMPONENT II (protein)
Unique Ligands	TRP

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1I3Z \| pdb_00001i3z	Download File View File

MURINE EAT2 SH2 DOMAIN IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

Lu, J., Poy, F., Morra, M., Terhorst, C., Eck, M.J.

(2001) Eur J Biochem 20: 5840-5852

Released	2003-04-08
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	EWS/FLI1 ACTIVATED TRANSCRIPT 2 (protein) SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE (protein)

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1IJQ \| pdb_00001ijq	Download File View File

Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair

Jeon, H., Meng, W., Takagi, J., Eck, M.J., Springer, T.A., Blacklow, S.C.

(2001) Nat Struct Biol 8: 499-504

Released	2001-05-23
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	LOW-DENSITY LIPOPROTEIN RECEPTOR (protein)

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1JPW \| pdb_00001jpw	Download File View File

Crystal Structure of a Human Tcf-4 / beta-Catenin Complex

Poy, F., Lepourcelet, M., Shivdasani, R.A., Eck, M.J.

(2001) Nat Struct Biol 8: 1053-1057

Released	2001-12-05
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	BETA-CATENIN (protein) transcription factor 7-like 2 (protein)

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1KSW \| pdb_00001ksw	Download File View File

Structure of Human c-Src Tyrosine Kinase (Thr338Gly Mutant) in Complex with N6-benzyl ADP

Witucki, L.A., Huang, X., Shah, K., Liu, Y., Kyin, S., Eck, M.J., Shokat, K.M.

(2002) Chem Biol 9: 25-33

Released	2002-02-27
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (protein)
Unique Ligands	NBS

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1L0Q \| pdb_00001l0q	Download File View File

Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein

Jing, H., Takagi, J., Liu, J.-H., Lindgren, S., Zhang, R.-G., Joachimiak, A., Wang, J.-H., Springer, T.A.

(2002) Structure 10: 1453-1464

Released	2002-11-06
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Methanosarcina mazei S-6
Macromolecule	Surface layer protein (protein)

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1L3E \| pdb_00001l3e	Download File View File

NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex

Freedman, S.J., Sun, Z.J., Poy, F., Kung, A.L., Livingston, D.M., Wagner, G., Eck, M.J.

(2002) Proc Natl Acad Sci U S A 99: 5367-5372

Released	2002-04-24
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	hypoxia inducible factor-1 alpha subunit (protein) p300 protein (protein)
Unique Ligands	ZN

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1LCJ \| pdb_00001lcj	Download File View File

SH2 (SRC HOMOLOGY-2) DOMAIN OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 11 RESIDUE PHOSPHOTYROSYL PEPTIDE EPQPYEEIPIYL

Eck, M., Harrison, S.

(1993) Nature 362: 87-91

Released	1995-10-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Hamster polyomavirus Homo sapiens
Macromolecule	P56==LCK== TYROSINE KINASE (protein) PHOSPHOPEPTIDE EPQ(PHOSPHO)YEEIPIYL (protein)

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1LCK \| pdb_00001lck	Download File View File

SH3-SH2 DOMAIN FRAGMENT OF HUMAN P56-LCK TYROSINE KINASE COMPLEXED WITH THE 10 RESIDUE SYNTHETIC PHOSPHOTYROSYL PEPTIDE TEGQPYQPQPA

Eck, M., Harrison, S.

(1994) Nature 368: 764-769

Released	1995-10-15
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	P56==LCK== TYROSINE KINASE (protein) TAIL PHOSPHOPEPTIDE TEGQ(PHOSPHO)YQPQPA (protein)

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1M27 \| pdb_00001m27	Download File View File

Crystal structure of SAP/FynSH3/SLAM ternary complex

Chan, B., Griesbach, J., Song, H.K., Poy, F., Terhorst, C., Eck, M.J.

(2003) Nat Cell Biol 5: 155-160

Released	2003-05-06
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Proto-oncogene tyrosine-protein kinase FYN (protein) SH2 domain protein 1A (protein) Signaling lymphocytic activation molecule (protein)
Unique Ligands	FLC

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1NCF \| pdb_00001ncf	Download File View File

A NEW PARADIGM FOR TUMOR NECROSIS FACTOR SIGNALLING

Naismith, J.H., Sprang, S.R.

(1995) J Biological Chem 270: 13303-13307

Released	1995-12-07
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	TUMOR NECROSIS FACTOR RECEPTOR (protein)

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1NHL \| pdb_00001nhl	Download File View File

SNAP-23N Structure

Freedman, S.J., Song, H.K., Xu, Y., Eck, M.J.

(2003) J Biological Chem 278: 13462-13467

Released	2003-04-15
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Synaptosomal-associated protein 23 (protein)

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1NTV \| pdb_00001ntv	Download File View File

Crystal Structure of the Disabled-1 (Dab1) PTB domain-ApoER2 peptide complex

Stolt, P.C., Jeon, H., Song, H.K., Herz, J., Eck, M.J., Blacklow, S.C.

(2003) Structure 11: 569-579

Released	2003-04-15
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Mus musculus
Macromolecule	Apolipoprotein E Receptor-2 peptide (protein) Disabled homolog 1 (protein)
Unique Ligands	PO4

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1NU2 \| pdb_00001nu2	Download File View File

Crystal structure of the murine Disabled-1 (Dab1) PTB domain-ApoER2 peptide-PI-4,5P2 ternary complex

Stolt, P.C., Jeon, H., Song, H.K., Herz, J., Eck, M.J., Blacklow, S.C.

(2003) Structure 11: 569-579

Released	2003-04-15
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Mus musculus
Macromolecule	Disabled homolog 1 (protein) peptide derived from murine Apolipoprotein E Receptor-2 (protein)
Unique Ligands	I3P

1 to 25 of 213 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1B47 | pdb_00001b47

1D1Z | pdb_00001d1z

1D4T | pdb_00001d4t

1D4W | pdb_00001d4w

1EG3 | pdb_00001eg3

1EG4 | pdb_00001eg4

1EXT | pdb_00001ext

1F3M | pdb_00001f3m

1FMK | pdb_00001fmk

1HCS | pdb_00001hcs

1HCT | pdb_00001hct

1I1Q | pdb_00001i1q

1I3Z | pdb_00001i3z

1IJQ | pdb_00001ijq

1JPW | pdb_00001jpw

1KSW | pdb_00001ksw

1L0Q | pdb_00001l0q

1L3E | pdb_00001l3e

1LCJ | pdb_00001lcj

1LCK | pdb_00001lck

1M27 | pdb_00001m27

1NCF | pdb_00001ncf

1NHL | pdb_00001nhl

1NTV | pdb_00001ntv

1NU2 | pdb_00001nu2