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234,136 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Dessen, A."

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Search Summary

This query matches 118 Structures.

Refinements

Structure Determination Methodology

experimental (118)

Scientific Name of Source Organism

	Streptococcus pneumoniae R6 (29)
	Escherichia coli (12)
	Streptococcus pneumoniae (9)
	Pseudomonas aeruginosa PAO1 (6)
	Escherichia coli K-12 (5)
	Glycine max (5)
	Saccharomyces cerevisiae (5)
	Streptococcus pneumoniae TIGR4 (5)
	Pseudomonas aeruginosa (4)
	Ebola virus sp. (3)

More...

Taxonomy

	Bacteria (104)
	Eukaryota (13)
	Riboviria (5)

Experimental Method

	X-RAY DIFFRACTION (114)
	ELECTRON MICROSCOPY (3)
	SOLUTION NMR (1)

Polymer Entity Type

	Protein (118)
	RNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (10)
	1.5 - 2.0 (34)
	2.0 - 2.5 (31)
	2.5 - 3.0 (28)
	3.0 - 3.5 (12)
	3.5 - 4.0 (2)

Release Date

	1995 - 1999 (11)
	2000 - 2004 (10)
	2005 - 2009 (23)
	2010 - 2014 (45)
	2015 - 2019 (14)
	2020 - 2024 (10)
	2025 - 2029 (5)

Enzyme Classification Name

	Transferases (28)
	Hydrolases (15)
	Ligases (24)
	Oxidoreductases (3)
	Lyases (1)

Membrane Protein Annotation

	OPM (5)
	PDBTM (1)

Symmetry Type

	Asymmetric (76)
	Cyclic (34)
	Dihedral (10)

SCOP Classification

	Alpha and beta proteins (a/b) (18)
	Alpha and beta proteins (a+b) (6)
	All beta proteins (11)
	Multi-domain proteins (alpha and beta) (9)
	Artifacts (13)
	Coiled coil proteins (2)

AllSelected

1 to 25 of 118 Structures

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1CJY \| pdb_00001cjy	Download File View File

HUMAN CYTOSOLIC PHOSPHOLIPASE A2

Dessen, A., Tang, J., Schmidt, H., Stahl, M., Clark, J.D., Seehra, J., Somers, W.S.

(1999) Cell 97: 349-360

Released	2000-04-20
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (CYTOSOLIC PHOSPHOLIPASE A2) (protein)
Unique Ligands	CA, MES

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1DB3 \| pdb_00001db3	Download File View File

E.COLI GDP-MANNOSE 4,6-DEHYDRATASE

Somoza, J.R., Menon, S., Somers, W.S., Sullivan, F.X.

(2000) Structure 8: 123-135

Released	1999-11-24
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	GDP-MANNOSE 4,6-DEHYDRATASE (protein)

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1ENV \| pdb_00001env	Download File View File

ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41

Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J., Wiley, D.C.

(1997) Nature 387: 426-430

Released	1997-11-19
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Human immunodeficiency virus 1 Saccharomyces cerevisiae
Macromolecule	HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41 (protein)

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1ENY \| pdb_00001eny	Download File View File

CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS

Dessen, A., Quemard, A., Blanchard, J.S., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(1995) Science 267: 1638-1641

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE (protein)
Unique Ligands	NAD

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1ENZ \| pdb_00001enz	Download File View File

CRYSTAL STRUCTURE AND FUNCTION OF THE ISONIAZID TARGET OF MYCOBACTERIUM TUBERCULOSIS

Dessen, A., Quemard, A., Blanchard, J.S., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(1995) Science 267: 1638-1641

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE (protein)
Unique Ligands	NAD

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1ES6 \| pdb_00001es6	Download File View File

CRYSTAL STRUCTURE OF THE MATRIX PROTEIN OF EBOLA VIRUS

Dessen, A., Volchkov, V., Dolnik, O., Klenk, H.-D., Weissenhorn, W.

(2000) EMBO J 19: 4228-4236

Released	2000-08-30
Method	X-RAY DIFFRACTION 2 Å
Organisms	Ebola virus sp.
Macromolecule	MATRIX PROTEIN VP40 (protein)

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1G9F \| pdb_00001g9f	Download File View File

CRYSTAL STRUCTURE OF THE SOYBEAN AGGLUTININ IN A COMPLEX WITH A BIANTENNARY BLOOD GROUP ANTIGEN ANALOG

Buts, L., Hamelryck, T.W., Dao-Thi, M.-H., Loris, R., Wyns, L., Etzler, M.E.

(2001) J Mol Biology 309: 193-201

Released	2001-06-13
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Glycine max
Macromolecule	LECTIN (protein)
Unique Ligands	CA, MN
Unique branched monosaccharides	GAL, NAG

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1H2C \| pdb_00001h2c	Download File View File

Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (High-resolution VP40[55-194] variant).

Gomis-Ruth, F.X., Dessen, A., Bracher, A., Klenk, H.D., Weissenhorn, W.

(2003) Structure 11: 423

Released	2003-04-10
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Ebola virus sp. Escherichia coli
Macromolecule	MATRIX PROTEIN VP40 (protein) 5'-R(UPGP*AP)-3' (nucleic acid)

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1H2D \| pdb_00001h2d	Download File View File

Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (Low-resolution VP40[31-212] variant).

Gomis-Ruth, F.X., Dessen, A., Bracher, A., Klenk, H.D., Weissenhorn, W.

(2003) Structure 11: 423

Released	2003-04-10
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Ebola virus sp. Escherichia coli
Macromolecule	MATRIX PROTEIN VP40 (protein) 5'-R(UPGP*AP)-3' (nucleic acid)
Unique Ligands	CL

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1K25 \| pdb_00001k25	Download File View File

PBP2x from a Highly Penicillin-resistant Streptococcus pneumoniae Clinical Isolate

Dessen, A., Mouz, N., Hopkins, J., Dideberg, O.

(2001) J Biological Chem 276: 45106-45112

Released	2001-10-31
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Streptococcus pneumoniae
Macromolecule	low-affinity PENICILLIN-BINDING PROTEIN 2X (protein)

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1PYY \| pdb_00001pyy	Download File View File

Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution

Chesnel, L., Pernot, L., Lemaire, D., Champelovier, D., Croize, J., Dideberg, O., Vernet, T., Zapun, A.

(2003) J Biological Chem 278: 44448-44456

Released	2003-09-30
Method	X-RAY DIFFRACTION 2.42 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	Penicillin-binding protein 2X (protein)
Unique Ligands	MPD, SO4
Unique branched monosaccharides	GLC, TRV

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1RP5 \| pdb_00001rp5	Download File View File

PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics

Pernot, L., Chesnel, L., Legouellec, A., Croize, J., Vernet, T., Dideberg, O., Dessen, A.

(2004) J Biological Chem 279: 16463-16470

Released	2004-02-03
Method	X-RAY DIFFRACTION 3 Å
Organisms	Streptococcus pneumoniae
Macromolecule	penicillin-binding protein 2x (protein)
Unique Ligands	SO4

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1SBD \| pdb_00001sbd	Download File View File

SOYBEAN AGGLUTININ COMPLEXED WITH 2,4-PENTASACCHARIDE

Dessen, A., Olsen, L.R., Gupta, D., Sabesan, S., Brewer, C.F., Sacchettini, J.C.

(1997) Biochemistry 36: 15073-15080

Released	1998-04-22
Method	X-RAY DIFFRACTION 2.52 Å
Organisms	Glycine max
Macromolecule	SOYBEAN AGGLUTININ (protein)
Unique Ligands	CA, MN
Unique branched monosaccharides	GAL, NAG

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1SBE \| pdb_00001sbe	Download File View File

SOYBEAN AGGLUTININ FROM GLYCINE MAX

Dessen, A., Olsen, L.R., Gupta, D., Sabesan, S., Sacchettini, J.C., Brewer, C.F.

(1997) Biochemistry 36: 15073-15080

Released	1998-04-22
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Glycine max
Macromolecule	SOYBEAN AGGLUTININ (protein)
Unique Ligands	CA, MN, NAG
Unique branched monosaccharides	GAL, NAG

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1SBF \| pdb_00001sbf	Download File View File

SOYBEAN AGGLUTININ

Olsen, L.R., Dessen, A., Gupta, D., Sabesan, S., Brewer, C.F., Sacchettini, J.C.

(1997) Biochemistry 36: 15073-15080

Released	1998-04-22
Method	X-RAY DIFFRACTION 2.43 Å
Organisms	Glycine max
Macromolecule	SOYBEAN AGGLUTININ (protein)
Unique Ligands	CA, MN
Unique branched monosaccharides	GAL, NAG

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1SZT \| pdb_00001szt	Download File View File

ATOMIC STRUCTURE OF A THERMOSTABLE SUBDOMAIN OF HIV-1 GP41

Tan, K., Lu, M., Wang, J.-H.

(1997) Proc Natl Acad Sci U S A 94: 12303-12308

Released	1997-12-24
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Human immunodeficiency virus 1
Macromolecule	HIV-1 ENVELOPE GLYCOPROTEIN GP41 (protein)

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1TFF \| pdb_00001tff	Download File View File

Structure of Otubain-2

Nanao, M.H., Tcherniuk, S.O., Chroboczek, J., Dideberg, O., Dessen, A., Balakirev, M.Y.

(2004) EMBO Rep 5: 783-788

Released	2004-08-03
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin thiolesterase protein OTUB2 (protein)

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1XP4 \| pdb_00001xp4	Download File View File

Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae

Morlot, C., Pernot, L., Le Gouellec, A., Di Guilmi, A.M., Vernet, T., Dideberg, O., Dessen, A.

(2005) J Biological Chem 280: 15984-15991

Released	2004-11-09
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	D-alanyl-D-alanine carboxypeptidase (protein)
Unique Ligands	IOD, SO4

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1ZID \| pdb_00001zid	Download File View File

LONG FATTY ACID CHAIN ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH AN ISONICOTINIC-ACYL-NADH INHIBITOR

Rozwarski, D.A., Jacobs Jr., W.R., Sacchettini, J.C., TB Structural Genomics Consortium (TBSGC)

(1998) Science 279: 98-102

Released	1998-03-25
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mycobacterium tuberculosis
Macromolecule	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE (protein)
Unique Ligands	ZID

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2BG1 \| pdb_00002bg1	Download File View File

Active site restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs)

Macheboeuf, P., Di Guilmi, A.M., Job, V., Vernet, T., Dideberg, O., Dessen, A.

(2005) Proc Natl Acad Sci U S A 102: 577

Released	2005-03-11
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	PENICILLIN-BINDING PROTEIN 1B (protein)
Unique Ligands	CL, SO4

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2C5W \| pdb_00002c5w	Download File View File

PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE

Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.

(2006) J Mol Biology 355: 684

Released	2005-12-07
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	PENICILLIN-BINDING PROTEIN 1A (protein)
Unique Ligands	CEF, CL, EDO, ZN

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2C6W \| pdb_00002c6w	Download File View File

PENICILLIN-BINDING PROTEIN 1A (PBP-1A) FROM STREPTOCOCCUS PNEUMONIAE

Contreras-Martel, C., Job, V., Di Guilmi, A.-M., Vernet, T., Dideberg, O., Dessen, A.

(2006) J Mol Biology 355: 684

Released	2005-12-07
Method	X-RAY DIFFRACTION 2.61 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	PENICILLIN-BINDING PROTEIN 1A (protein)
Unique Ligands	CL, ZN

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2JCH \| pdb_00002jch	Download File View File

Structural and mechanistic basis of penicillin binding protein inhibition by lactivicins

Macheboeuf, P., Fisher, D.S., Brown, T.J., Zervosen, A., Luxen, A., Joris, B., Dessen, A., Schofield, C.J.

(2007) Nat Chem Biol 3: 565

Released	2007-08-14
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	PENICILLIN-BINDING PROTEIN 1B (protein)
Unique Ligands	CL, EDO, PL7, SO4

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2JE5 \| pdb_00002je5	Download File View File

STRUCTURAL AND MECHANISTIC BASIS OF PENICILLIN BINDING PROTEIN INHIBITION BY LACTIVICINS

Macheboeuf, P., Fisher, D.S., Brown, T.J., Zervosen, A., Luxen, A., Joris, B., Dessen, A., Schofield, C.J.

(2007) Nat Chem Biol 3: 565

Released	2007-08-14
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Streptococcus pneumoniae R6
Macromolecule	PENICILLIN-BINDING PROTEIN 1B (protein)
Unique Ligands	CL, L4C, SO4

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2JFF \| pdb_00002jff	Download File View File

Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor

Kotnik, M., Humljan, J., Contreras-Martel, C., Oblak, M., Kristan, K., Herve, M., Blanot, D., Urleb, U., Gobec, S., Dessen, A., Solmajer, T.

(2007) J Mol Biology 370: 107

Released	2007-05-15
Method	X-RAY DIFFRACTION 1.89 Å
Organisms	Escherichia coli
Macromolecule	UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE (protein)
Unique Ligands	LK2, SO4

1 to 25 of 118 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1CJY | pdb_00001cjy

1DB3 | pdb_00001db3

1ENV | pdb_00001env

1ENY | pdb_00001eny

1ENZ | pdb_00001enz

1ES6 | pdb_00001es6

1G9F | pdb_00001g9f

1H2C | pdb_00001h2c

1H2D | pdb_00001h2d

1K25 | pdb_00001k25

1PYY | pdb_00001pyy

1RP5 | pdb_00001rp5

1SBD | pdb_00001sbd

1SBE | pdb_00001sbe

1SBF | pdb_00001sbf

1SZT | pdb_00001szt

1TFF | pdb_00001tff

1XP4 | pdb_00001xp4

1ZID | pdb_00001zid

2BG1 | pdb_00002bg1

2C5W | pdb_00002c5w

2C6W | pdb_00002c6w

2JCH | pdb_00002jch

2JE5 | pdb_00002je5

2JFF | pdb_00002jff