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234,785 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Zhao, K."

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Search Summary

This query matches 59 Structures.

Refinements

Structure Determination Methodology

experimental (59)

Scientific Name of Source Organism

	Homo sapiens (34)
	Saccharomyces cerevisiae (9)
	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (5)
	Mus musculus (4)
	Archaeoglobus fulgidus (2)
	Drosophila melanogaster (2)
	Escherichia coli (2)
	Pseudomonas aeruginosa (2)
	Gloydius halys (1)
	Human papillomavirus type 1a (1)

More...

Taxonomy

	Eukaryota (50)
	Eukaryota (eukaryotes) (5)
	Bacteria (4)
	Archaea (2)
	Monodnaviria (1)
	Riboviria (1)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (44)
	ELECTRON MICROSCOPY (15)

Polymer Entity Type

	Protein (59)
	RNA (2)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (15)
	2.0 - 2.5 (18)
	2.5 - 3.0 (14)
	3.0 - 3.5 (6)
	3.5 - 4.0 (2)
	4.0 - 4.5 (1)
	> 4.5 (1)

Release Date

	1995 - 1999 (1)
	2000 - 2004 (9)
	2005 - 2009 (9)
	2010 - 2014 (6)
	2015 - 2019 (11)
	2020 - 2024 (23)

Enzyme Classification Name

	Transferases (26)
	Hydrolases (7)
	Oxidoreductases (4)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (41)
	Cyclic (18)
	Helical (3)
	Dihedral (1)

SCOP Classification

	Alpha and beta proteins (a/b) (9)
	Artifacts (8)
	All beta proteins (5)
	Alpha and beta proteins (a+b) (5)
	All alpha proteins (2)
	Small proteins (1)

AllSelected

1 to 25 of 59 Structures

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1HU8 \| pdb_00001hu8	Download File View File

CRYSTAL STRUCTURE OF THE MOUSE P53 CORE DNA-BINDING DOMAIN AT 2.7A RESOLUTION

Zhao, K., Chai, X., Johnston, K., Clements, A., Marmorstein, R.

(2001) J Biological Chem 276: 12120-12127

Released	2001-07-04
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Mus musculus
Macromolecule	CELLULAR TUMOR ANTIGEN P53 (protein)
Unique Ligands	ZN

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1JIA \| pdb_00001jia	Download File View File

STRUCTURE OF A BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS AT 2.13A RESOLUTION

Zhao, K., Lin, Z.

(1998) Acta Crystallogr D Biol Crystallogr 54: 510-521

Released	1998-06-10
Method	X-RAY DIFFRACTION 2.13 Å
Organisms	Gloydius halys
Macromolecule	PHOSPHOLIPASE A2 (protein)
Unique Ligands	CA

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1NFH \| pdb_00001nfh	Download File View File

Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding

Zhao, K., Chai, X., Marmorstein, R.

(2003) J Biological Chem 278: 26071-26077

Released	2003-08-05
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Archaeoglobus fulgidus
Macromolecule	conserved hypothetical protein AF1956 (protein)

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1NFJ \| pdb_00001nfj	Download File View File

Structure of a Sir2 substrate, alba, reveals a mechanism for deactylation-induced enhancement of DNA-binding

Zhao, K., Chai, X., Marmorstein, R.

(2003) J Biological Chem 278: 26071-26077

Released	2003-08-05
Method	X-RAY DIFFRACTION 2 Å
Organisms	Archaeoglobus fulgidus
Macromolecule	conserved hypothetical protein AF1956 (protein)

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1Q14 \| pdb_00001q14	Download File View File

Structure and autoregulation of the yeast Hst2 homolog of Sir2

Zhao, K., Chai, X., Clements, A., Marmorstein, R.

(2003) Nat Struct Biol 10: 864-871

Released	2003-09-30
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	HST2 protein (protein)
Unique Ligands	CL, ZN

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1Q17 \| pdb_00001q17	Download File View File

Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide

Zhao, K., Chai, X., Marmorstein, R.

(2003) Structure 11: 1403-1411

Released	2003-11-18
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	HST2 protein (protein)
Unique Ligands	APR, CL, ZN

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1Q1A \| pdb_00001q1a	Download File View File

Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide

Zhao, K., Chai, X., Marmorstein, R.

(2003) Structure 11: 1403-1411

Released	2003-11-18
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Saccharomyces cerevisiae Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	HST2 protein (protein) Histone H4 (protein)
Unique Ligands	OAD, ZN

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1S5P \| pdb_00001s5p	Download File View File

Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Eschericia coli.

Zhao, K., Chai, X., Marmorstein, R.

(2004) J Mol Biology 337: 731-741

Released	2004-03-23
Method	X-RAY DIFFRACTION 1.96 Å
Organisms	Escherichia coli
Macromolecule	HISTONE H4 (RESIDUES 12-19) (protein) NAD-dependent deacetylase (protein)
Unique Ligands	ZN

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1SZC \| pdb_00001szc	Download File View File

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases

Zhao, K., Harshaw, R., Chai, X., Marmorstein, R.

(2004) Proc Natl Acad Sci U S A 101: 8563-8568

Released	2004-06-15
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Saccharomyces cerevisiae Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	Histone H4 peptide (protein) NAD-dependent deacetylase HST2 (protein)
Unique Ligands	CL, CNA, GOL, ZN

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1SZD \| pdb_00001szd	Download File View File

Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases

Zhao, K., Harshaw, R., Chai, X., Marmorstein, R.

(2004) Proc Natl Acad Sci U S A 101: 8563-8568

Released	2004-06-15
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Saccharomyces cerevisiae Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	Histone H4 peptide (protein) NAD-dependent deacetylase HST2 (protein)
Unique Ligands	APR, CL, GOL, ZN

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1ZX2 \| pdb_00001zx2	Download File View File

Crystal Structure of Yeast UBP3-associated Protein BRE5

Li, K., Zhao, K., Ossareh-Nazari, B., Da, G., Dargemont, C., Marmorstein, R.

(2005) J Biological Chem 280: 29176-29185

Released	2005-06-21
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	UBP3-associated protein BRE5 (protein)

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2B9D \| pdb_00002b9d	Download File View File

Crystal Structure of HPV E7 CR3 domain

Liu, X., Clements, A., Zhao, K., Marmorstein, R.

(2006) J Biological Chem 281: 578-586

Released	2005-10-25
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Human papillomavirus type 1a
Macromolecule	E7 protein (protein)
Unique Ligands	ZN

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2FQ3 \| pdb_00002fq3	Download File View File

Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes

Da, G., Lenkart, J., Zhao, K., Shiekhattar, R., Cairns, B.R., Marmorstein, R.

(2006) Proc Natl Acad Sci U S A 103: 2057-2062

Released	2006-02-07
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Transcription regulatory protein SWI3 (protein)

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2IOI \| pdb_00002ioi	Download File View File

Crystal structure of the mouse p53 core domain at 1.55 A

Ho, W.C., Luo, C., Zhao, K., Chai, X., Fitzgerald, M.X., Marmorstein, R.

(2006) Acta Crystallogr D Biol Crystallogr 62: 1484-1493

Released	2006-12-05
Method	X-RAY DIFFRACTION 1.55 Å
Organisms	Mus musculus
Macromolecule	Cellular tumor antigen p53 (protein)
Unique Ligands	TRS, ZN

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2IOM \| pdb_00002iom	Download File View File

Mouse p53 core domain soaked with 2-propanol

Ho, W.C., Luo, C., Zhao, K., Chai, X., Fitzgerald, M.X., Marmorstein, R.

(2006) Acta Crystallogr D Biol Crystallogr 62: 1484-1493

Released	2006-12-05
Method	X-RAY DIFFRACTION 2 Å
Organisms	Mus musculus
Macromolecule	Cellular tumor antigen p53 (protein)
Unique Ligands	IPA, TRS, ZN

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2IOO \| pdb_00002ioo	Download File View File

Crystal structure of the mouse p53 core domain

Ho, W.C., Luo, C., Zhao, K., Chai, X., Fitzgerald, M.X., Marmorstein, R.

(2006) Acta Crystallogr D Biol Crystallogr 62: 1484-1493

Released	2006-12-05
Method	X-RAY DIFFRACTION 2.02 Å
Organisms	Mus musculus
Macromolecule	Cellular tumor antigen p53 (protein)
Unique Ligands	ZN

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2QQF \| pdb_00002qqf	Download File View File

Hst2 bound to ADP-HPD and Acetylated histone H4

Marmorstein, R., Sanders, B.D., Zhao, K., Slama, J.

(2007) Mol Cell 25: 463-472

Released	2007-10-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Saccharomyces cerevisiae Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	Histone H4 (protein) NAD-dependent deacetylase HST2 (protein)
Unique Ligands	A1R, ZN

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2QQG \| pdb_00002qqg	Download File View File

Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide

Marmorstein, R., Sanders, B., Zhao, K., Slama, J.

(2007) Mol Cell 25: 463-472

Released	2007-10-09
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Saccharomyces cerevisiae Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Macromolecule	Histone H4 (protein) NAD-dependent deacetylase HST2 (protein)
Unique Ligands	A1R, NCA, ZN

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2YB8 \| pdb_00002yb8	Download File View File

Crystal structure of Nurf55 in complex with Su(z)12

Schmitges, F.W., Prusty, A.B., Faty, M., Stutzer, A., Lingaraju, G.M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R.D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., Thoma, N.H.

(2011) Mol Cell 42: 330

Released	2011-05-18
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Drosophila melanogaster
Macromolecule	POLYCOMB PROTEIN SU(Z)12 (protein) PROBABLE HISTONE-BINDING PROTEIN CAF1 (protein)
Unique Ligands	SO4

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2YBA \| pdb_00002yba	Download File View File

Crystal structure of Nurf55 in complex with histone H3

(2011) Mol Cell 42: 330

Released	2011-05-11
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Drosophila melanogaster
Macromolecule	HISTONE H3 (protein) PROBABLE HISTONE-BINDING PROTEIN CAF1 (protein)

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3BIY \| pdb_00003biy	Download File View File

Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA

Liu, X., Wang, L., Zhao, K., Thompson, P.R., Hwang, Y., Marmorstein, R., Cole, P.A.

(2008) Nature 451: 846-850

Released	2008-02-12
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	Histone acetyltransferase p300 (protein)
Unique Ligands	01K, BR

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3TG4 \| pdb_00003tg4	Download File View File

Structure of SMYD2 in complex with SAM

Zhao, K., Wang, L.

(2011) J Biological Chem

Released	2011-08-31
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	N-lysine methyltransferase SMYD2 (protein)
Unique Ligands	GOL, SAM, ZN

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3TG5 \| pdb_00003tg5	Download File View File

Structure of SMYD2 in complex with p53 and SAH

Zhao, K., Wang, L.

(2011) J Biological Chem

Released	2011-08-31
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Cellular tumor antigen p53 (protein) N-lysine methyltransferase SMYD2 (protein)
Unique Ligands	GOL, SAH, ZN

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4MZ7 \| pdb_00004mz7	Download File View File

Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase

Zhu, C., Gao, W., Zhao, K., Qin, X., Zhang, Y., Peng, X., Zhang, L., Dong, Y., Zhang, W., Li, P., Wei, W., Gong, Y., Yu, X.F.

(2013) Nat Commun 4: 2722-2722

Released	2013-11-20
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (protein)
Unique Ligands	DGT, DTP, MG, ZN