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234,440 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Wu, H."

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Search Summary

This query matches 488 Structures.

Refinements

Structure Determination Methodology

experimental (488)

Scientific Name of Source Organism

	Homo sapiens (318)
	Rattus norvegicus (23)
	Mus musculus (21)
	synthetic construct (17)
	Saccharomyces cerevisiae S288C (16)
	Escherichia coli K-12 (15)
	Danio rerio (14)
	Xenopus laevis (12)
	Escherichia coli (10)
	Olivierus martensii (10)

More...

Taxonomy

	Eukaryota (414)
	Bacteria (80)
	other sequences (17)
	Eukaryota (eukaryotes) (10)
	Duplodnaviria (8)
	Riboviria (5)
	Archaea (4)
	Monodnaviria (3)
	Varidnaviria (2)
	Viruses incertae sedis (2)

Experimental Method

	X-RAY DIFFRACTION (313)
	ELECTRON MICROSCOPY (113)
	SOLUTION NMR (60)
	SOLID-STATE NMR (2)

Polymer Entity Type

	Protein (481)
	DNA (33)
	RNA (9)

Refinement Resolution (Å)

	1.0 - 1.5 (12)
	1.5 - 2.0 (115)
	2.0 - 2.5 (108)
	2.5 - 3.0 (63)
	3.0 - 3.5 (55)
	3.5 - 4.0 (29)
	4.0 - 4.5 (20)
	> 4.5 (24)

Release Date

	1990 - 1994 (2)
	1995 - 1999 (9)
	2000 - 2004 (40)
	2005 - 2009 (102)
	2010 - 2014 (105)
	2015 - 2019 (132)
	2020 - 2024 (97)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (202)
	Hydrolases (86)
	Oxidoreductases (13)
	Ligases (11)
	Lyases (9)
	Translocases (4)
	Isomerases (3)

Membrane Protein Annotation

	PDBTM (46)
	mpstruc (31)
	OPM (35)
	MemProtMD (27)

Symmetry Type

	Asymmetric (291)
	Cyclic (168)
	Dihedral (26)
	Helical (17)
	Icosahedral (3)

SCOP Classification

	All beta proteins (70)
	Alpha and beta proteins (a/b) (61)
	Alpha and beta proteins (a+b) (64)
	Coiled coil proteins (26)
	Artifacts (26)
	All alpha proteins (10)
	Small proteins (13)
	Membrane and cell surface proteins and peptides (9)
	Peptides (2)

AllSelected

1 to 25 of 488 Structures

Page 1 of 20

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1CA4 \| pdb_00001ca4	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2)

Park, Y.C., Burkitt, V., Villa, A.R., Tong, L., Wu, H.

(1999) Nature 398: 533-538

Released	1999-04-12
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2) (protein)

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1CA9 \| pdb_00001ca9	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2

Park, Y.C., Burkitt, V., Villa, A.R., Tong, L., Wu, H.

(1999) Nature 398: 533-538

Released	1999-04-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2) (protein) PROTEIN (TNF-R2) (protein)

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1CDJ \| pdb_00001cdj	Download File View File

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4

Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.

(1996) Proc Natl Acad Sci U S A 93: 15030-15035

Released	1997-04-01
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	T-CELL SURFACE GLYCOPROTEIN CD4 (protein)

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1CDU \| pdb_00001cdu	Download File View File

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH PHE 43 REPLACED BY VAL

Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.

(1996) Proc Natl Acad Sci U S A 93: 15030-15035

Released	1997-04-01
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	T-CELL SURFACE GLYCOPROTEIN CD4 (protein)

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1CDY \| pdb_00001cdy	Download File View File

STRUCTURE OF T-CELL SURFACE GLYCOPROTEIN CD4 MUTANT WITH GLY 47 REPLACED BY SER

Wu, H., Myszka, D., Tendian, S.W., Brouillette, C.G., Sweet, R.W., Chaiken, I.M., Hendrickson, W.A.

(1996) Proc Natl Acad Sci U S A 93: 15030-15035

Released	1997-04-01
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	T-CELL SURFACE GLYCOPROTEIN CD4 (protein)

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1CZY \| pdb_00001czy	Download File View File

CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE TRAF DOMAIN OF HUMAN TRAF2 AND AN LMP1 BINDING PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Epstein-Barr virus (strain B95-8) Homo sapiens
Macromolecule	LATENT MEMBRANE PROTEIN 1 (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1CZZ \| pdb_00001czz	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 17-RESIDUE CD40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	CD 40 PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D00 \| pdb_00001d00	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 5-RESIDUE CD40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-29
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	B-CELL SURFACE ANTIGEN CD40 (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D01 \| pdb_00001d01	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A HUMAN CD30 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2003-12-02
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	CD30 PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2 (protein)

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1D0A \| pdb_00001d0a	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2) IN COMPLEX WITH A HUMAN OX40 PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	OX40L RECEPTOR PEPTIDE (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1D0J \| pdb_00001d0j	Download File View File

STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A M4-1BB PEPTIDE

Ye, H., Park, Y.C., Kreishman, M., Kieff, E., Wu, H.

(1999) Mol Cell 4: 321-330

Released	2000-03-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	4-1BB LIGAND RECEPTOR (protein) TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2 (protein)

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1DIA \| pdb_00001dia	Download File View File

HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY249543

Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.

(2000) Biochemistry 39: 6325-6335

Released	2000-07-05
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE (protein)
Unique Ligands	L24, NAP

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1DIB \| pdb_00001dib	Download File View File

HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899

Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.

(2000) Biochemistry 39: 6325-6335

Released	2000-07-05
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE (protein)
Unique Ligands	L34, NAP

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1DIG \| pdb_00001dig	Download File View File

HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY374571

Schmidt, A., Wu, H., MacKenzie, R.E., Chen, V.J., Bewly, J.R., Ray, J.E., Toth, J.E., Cygler, M.

(2000) Biochemistry 39: 6325-6335

Released	2000-07-05
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE (protein)
Unique Ligands	ACT, L37, NAP

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1F3V \| pdb_00001f3v	Download File View File

Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2

Park, Y.C., Ye, H., Hsia, C., Segal, D., Rich, R., Liou, H.-C., Myszka, D., Wu, H.

(2000) Cell 101: 777-787

Released	2000-09-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN (protein) TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEIN (protein)

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1FB9 \| pdb_00001fb9	Download File View File

EFFECTS OF S-SULFONATION ON THE SOLUTION STRUCTURE OF SALMON CALCITONIN

Wu, H., Mao, J., Wang, Y., Dou, H.

(2003) Biochem Biophys Res Commun 306: 582-589

Released	2003-07-01
Method	SOLUTION NMR
Organisms	Oncorhynchus gorbuscha
Macromolecule	CALCITONIN ANALOGUE (protein)

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1FLK \| pdb_00001flk	Download File View File

MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3

Ni, C.-Z., Welsh, K., Leo, E., Chiou, C.-K., Wu, H., Reed, J.C., Ely, K.R.

(2000) Proc Natl Acad Sci U S A 97: 10395-10399

Released	2000-10-18
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	TNF RECEPTOR ASSOCIATED FACTOR 3 (protein)

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1FLL \| pdb_00001fll	Download File View File

MOLECULAR BASIS FOR CD40 SIGNALING MEDIATED BY TRAF3

Ni, C.-Z., Welsh, K., Leo, E., Chiou, C.-K., Wu, H., Reed, J.C., Ely, K.R.

(2000) Proc Natl Acad Sci U S A 97: 10395-10399

Released	2000-10-18
Method	X-RAY DIFFRACTION 3.5 Å
Organisms	Homo sapiens
Macromolecule	B-CELL SURFACE ANTIGEN CD40 (protein) TNF RECEPTOR ASSOCIATED FACTOR 3 (protein)

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1FRY \| pdb_00001fry	Download File View File

THE SOLUTION STRUCTURE OF SHEEP MYELOID ANTIMICROBIAL PEPTIDE, RESIDUES 1-29 (SMAP29)

Tack, B.F., Sawai, M.V., Kearney, W.R., Robertson, A.D., Sherman, M.A., Wang, W., Hong, T., Boo, L.M., Wu, H., Waring, A.J., Lehrer, R.I.

(2002) Eur J Biochem 269: 1181-1189

Released	2002-03-08
Method	SOLUTION NMR
Organisms	Ovis aries
Macromolecule	MYELOID ANTIMICROBIAL PEPTIDE (protein)

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1HCN \| pdb_00001hcn	Download File View File

STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN

Wu, H., Lustbader, J.W., Liu, Y., Canfield, R.E., Hendrickson, W.A.

(1994) Structure 2: 545-558

Released	1994-09-30
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	HUMAN CHORIONIC GONADOTROPIN (protein)
Unique Ligands	NAG

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1I4E \| pdb_00001i4e	Download File View File

CRYSTAL STRUCTURE OF THE CASPASE-8/P35 COMPLEX

Xu, G., Cirilli, M., Huang, Y., Rich, R.L., Myszka, D.G., Wu, H.

(2001) Nature 410: 494-497

Released	2001-03-28
Method	X-RAY DIFFRACTION 3 Å
Organisms	Autographa californica nucleopolyhedrovirus Homo sapiens
Macromolecule	Caspase-8 (protein) Early 35 kDa protein (protein)

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1I4O \| pdb_00001i4o	Download File View File

CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX

Huang, Y., Park, Y.C., Rich, R.L., Segal, D., Myszka, D.G., Wu, H.

(2001) Cell 104: 781-790

Released	2001-03-21
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4 (protein) CASPASE-7 (protein)