RCSB PDB: Search

2J8A \| pdb_00002j8a	Download File View File

X-ray structure of the N-terminus RRM domain of Set1

Tresaugues, L., Dehe, P.M., Guerois, R., Rodriguez-Gil, A., Varlet, I., Salah, P., Pamblanco, M., Luciano, P., Quevillon-Cheruel, S., Sollier, J., Leulliot, N., Couprie, J., Tordera, V., Zinn-Justin, S., Chavez, S., Van Tilbeurgh, H., Geli, V.

To be published

Released	2007-03-20
Method	X-RAY DIFFRACTION 3 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC (protein)

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2JIS \| pdb_00002jis	Download File View File

Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.

Collins, R., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

To be published

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	CYSTEINE SULFINIC ACID DECARBOXYLASE (protein)
Unique Ligands	NO3, PLP

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2QK4 \| pdb_00002qk4	Download File View File

Human glycinamide ribonucleotide synthetase

Lehtio, L., Welin, M., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

(2010) Nucleic Acids Res 38: 7308-7319

Released	2007-07-24
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Homo sapiens
Macromolecule	Trifunctional purine biosynthetic protein adenosine-3 (protein)
Unique Ligands	ATP, CL, GOL, SO4

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2QQ2 \| pdb_00002qq2	Download File View File

Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7

Busam, R., Lehtio, L., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

To be published

Released	2007-08-14
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Cytosolic acyl coenzyme A thioester hydrolase (protein)

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2R55 \| pdb_00002r55	Download File View File

Human StAR-related lipid transfer protein 5

Lehtio, L., Busam, R.D., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e19521-e19521

Released	2007-09-18
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	StAR-related lipid transfer protein 5 (protein)

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2RF5 \| pdb_00002rf5	Download File View File

Crystal structure of human tankyrase 1- catalytic PARP domain

Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)

(2008) J Mol Biology 379: 136-145

Released	2007-10-09
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Tankyrase-1 (protein)
Unique Ligands	GOL, ZN

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2V40 \| pdb_00002v40	Download File View File

Human Adenylosuccinate synthetase isozyme 2 in complex with GDP

Welin, M., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-07-10
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 (protein)
Unique Ligands	GDP

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2V4M \| pdb_00002v4m	Download File View File

The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with fructose 6-phosphate

Moche, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, S., Schueler, H., Thorsell, A.G., Tresaugues, L., Uppenberg, J., Van Den Berg, S., Welin, M., Wisniewska, M., Weigelt, J., Nordlund, P., Wikstrom, M.

To be published

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Homo sapiens
Macromolecule	GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 (protein)
Unique Ligands	CL, F6R

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2V4U \| pdb_00002v4u	Download File View File

Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L- NORLEUCINE

Welin, M., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wisniewska, M., Weigelt, J., Wikstrom, M., Nordlund, P.

To be published

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	CTP SYNTHASE 2 (protein)

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2V9Y \| pdb_00002v9y	Download File View File

Human aminoimidazole ribonucleotide synthetase

Welin, M., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

(2010) Nucleic Acids Res 38: 7308

Released	2007-09-11
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (protein)
Unique Ligands	SO4

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2VD6 \| pdb_00002vd6	Download File View File

Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate.

Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-10-23
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	ADENYLOSUCCINATE LYASE (protein)
Unique Ligands	2SA, AMP, CL, FUM, GOL

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2VKQ \| pdb_00002vkq	Download File View File

Crystal structure of human cytosolic 5'-nucleotidase III (cN-III, NT5C3) in complex with beryllium trifluoride

Wallden, K., Moche, M., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2008-01-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	CYTOSOLIC 5'-NUCLEOTIDASE III (protein)
Unique Ligands	BEF, MG

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2VKT \| pdb_00002vkt	Download File View File

HUMAN CTP SYNTHETASE 2 - GLUTAMINASE DOMAIN

Welin, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2008-01-15
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	CTP SYNTHASE 2 (protein)

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2VM5 \| pdb_00002vm5	Download File View File

HUMAN BIR2 DOMAIN OF BACULOVIRAL INHIBITOR OF APOPTOSIS REPEAT- CONTAINING 1 (BIRC1)

Herman, M.D., Welin, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

(2009) Acta Crystallogr Sect F Struct Biol Cryst Commun 65: 1091

Released	2008-01-29
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 1 (protein)
Unique Ligands	GOL, ZN

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2VM6 \| pdb_00002vm6	Download File View File

Human Bcl2-A1 in complex with Bim-BH3 peptide

Herman, M.D., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

(2008) FEBS Lett 582: 3590

Released	2008-02-05
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	BCL-2-LIKE PROTEIN 11 (protein) BCL-2-RELATED PROTEIN A1 (protein)
Unique Ligands	SO4

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2VPI \| pdb_00002vpi	Download File View File

Human GMP synthetase - glutaminase domain

Welin, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Van Der Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2008-03-11
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	GMP SYNTHASE (protein)

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2VR2 \| pdb_00002vr2	Download File View File

Human Dihydropyrimidinase

Welin, M., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2008-04-01
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	DIHYDROPYRIMIDINASE (protein)
Unique Ligands	CL, ZN

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2VUX \| pdb_00002vux	Download File View File

Human ribonucleotide reductase, subunit M2 B

Welin, M., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Svensson, L., Thorsell, A.G., Tresaugues, L., van Den Berg, S., Weigelt, J., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2008-07-15
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B (protein)
Unique Ligands	FE

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2VXO \| pdb_00002vxo	Download File View File

Human GMP synthetase in complex with XMP

Welin, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wisniewska, M., Wikstrom, M., Nordlund, P.

(2013) J Mol Biology 425: 4323

Released	2008-08-12
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	GMP SYNTHASE [GLUTAMINE-HYDROLYZING] (protein)
Unique Ligands	SO4, XMP

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2W4L \| pdb_00002w4l	Download File View File

Human dCMP deaminase

Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schuler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P.

To be published

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	DEOXYCYTIDYLATE DEAMINASE (protein)
Unique Ligands	CL, ZN

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2W7T \| pdb_00002w7t	Download File View File

Trypanosoma brucei CTPS - glutaminase domain with bound acivicin

Welin, M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2009-01-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Trypanosoma brucei
Macromolecule	PUTATIVE CYTIDINE TRIPHOSPHATE SYNTHASE (protein)
Unique Ligands	CL

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2WEF \| pdb_00002wef	Download File View File

Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, PO4 and Magnesium

Moche, M., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Der Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2009-04-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	3'(2')\, 5'-BISPHOSPHATE NUCLEOTIDASE 1 (protein)
Unique Ligands	AMP, MG, PO4

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2WGH \| pdb_00002wgh	Download File View File

Human Ribonucleotide reductase R1 subunit (RRM1) in complex with dATP and Mg.

Welin, R.M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kragh-Nielsen, T., Kotzsch, A., Kotenyova, T., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Schutz, P., Siponen, M.I., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wisniewska, M., Nordlund, P.

(2011) Nat Struct Mol Biol 18: 316

Released	2009-05-05
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT (protein)
Unique Ligands	DTP, GOL, MG