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1DJN \| pdb_00001djn	Download File View File

STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT WILD TYPE TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1)

Trickey, P., Basran, J., Lian, L.-Y., Chen, Z.-W., Barton, J.D., Sutcliffe, M.J., Scrutton, N.S., Mathews, F.S.

(2000) Biochemistry 39: 7678-7688

Released	1999-12-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methylophilus methylotrophus W3A1
Macromolecule	TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, FMN, SF4

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1DJQ \| pdb_00001djq	Download File View File

STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT C30A MUTANT OF TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1)

Trickey, P., Basran, J., Lian, L.-Y., Chen, Z.-W., Barton, J.D., Sutcliffe, M.J., Scrutton, N.S., Mathews, F.S.

(2000) Biochemistry 39: 7678-7688

Released	1999-12-22
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methylophilus methylotrophus W3A1
Macromolecule	TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, FMN, SF4

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1O94 \| pdb_00001o94	Download File View File

Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein

Leys, D., Basran, J., Talfournier, F., Sutcliffe, M.J., Scrutton, N.S.

(2003) Nat Struct Biol 10: 219

Released	2003-02-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Methylophilus methylotrophus
Macromolecule	ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT (protein) ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT (protein) TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, AMP, FMN, SF4

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1O95 \| pdb_00001o95	Download File View File

Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein

Leys, D., Basran, J., Talfournier, F., Sutcliffe, M.J., Scrutton, N.S.

(2003) Nat Struct Biol 10: 219

Released	2003-02-06
Method	X-RAY DIFFRACTION 3.7 Å
Organisms	Methylophilus methylotrophus
Macromolecule	ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT (protein) ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT (protein) TRIMETHYLAMINE DEHYDROGENASE (protein)
Unique Ligands	ADP, AMP, FMN, SF4

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1O96 \| pdb_00001o96	Download File View File

Structure of electron transferring flavoprotein for Methylophilus methylotrophus.

Leys, D., Basran, J., Talfournier, F., Sutcliffe, M.J., Scrutton, N.S.

(2003) Nat Struct Biol 10: 219

Released	2003-02-06
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Methylophilus methylotrophus
Macromolecule	ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT (protein) ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT (protein)
Unique Ligands	AMP, FAD

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1O97 \| pdb_00001o97	Download File View File

Structure of electron transferring flavoprotein from Methylophilus methylotrophus, recognition loop removed by limited proteolysis

Leys, D., Basran, J., Talfournier, F., Sutcliffe, M.J., Scrutton, N.S.

(2003) Nat Struct Biol 10: 219

Released	2003-02-06
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Methylophilus methylotrophus
Macromolecule	ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT (protein) ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT (protein)
Unique Ligands	AMP, FAD

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1PJ5 \| pdb_00001pj5	Download File View File

Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate

Leys, D., Basran, J., Scrutton, N.S.

(2003) EMBO J 22: 4038-4048

Released	2003-10-07
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Arthrobacter globiformis
Macromolecule	N,N-dimethylglycine oxidase (protein)
Unique Ligands	ACT, FAD, NA

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1PJ6 \| pdb_00001pj6	Download File View File

Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folic acid

Leys, D., Basran, J., Scrutton, N.S.

(2003) EMBO J 22: 4038-4048

Released	2003-10-07
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Arthrobacter globiformis
Macromolecule	N,N-dimethylglycine oxidase (protein)
Unique Ligands	FAD, FOL, NA

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1PJ7 \| pdb_00001pj7	Download File View File

Structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folinic acid

Leys, D., Basran, J., Scrutton, N.S.

(2003) EMBO J 22: 4038-4048

Released	2003-10-07
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Arthrobacter globiformis
Macromolecule	N,N-dimethylglycine oxidase (protein)
Unique Ligands	FAD, FFO, NA

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1S24 \| pdb_00001s24	Download File View File

Rubredoxin domain II from Pseudomonas oleovorans

Perry, A., Tambyrajah, W., Grossmann, J.G., Lian, L.Y., Scrutton, N.S.

(2004) Biochemistry 43: 3167-3182

Released	2004-05-04
Method	SOLUTION NMR
Organisms	Ectopseudomonas oleovorans
Macromolecule	Rubredoxin 2 (protein)
Unique Ligands	CD

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1T9G \| pdb_00001t9g	Download File View File

Structure of the human MCAD:ETF complex

Toogood, H.S., van Thiel, A., Basran, J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2004) J Biological Chem 279: 32904-32912

Released	2004-06-08
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial (protein) Electron transfer flavoprotein alpha-subunit, mitochondrial (protein) Electron transfer flavoprotein beta-subunit (protein)
Unique Ligands	AMP, FAD

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2A1T \| pdb_00002a1t	Download File View File

Structure of the human MCAD:ETF E165betaA complex

Toogood, H.S., Van Thiel, A., Scrutton, N.S., Leys, D.

(2005) J Biological Chem 280: 30361-30366

Released	2005-07-05
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Acyl-CoA dehydrogenase, medium-chain specific, mitochondrial precursor (protein) Electron transfer flavoprotein alpha-subunit, mitochondrial precursor (protein) Electron transfer flavoprotein beta-subunit (protein)
Unique Ligands	AMP, FAD

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2A1U \| pdb_00002a1u	Download File View File

Crystal structure of the human ETF E165betaA mutant

Toogood, H.S., Van Thiel, A., Scrutton, N.S., Leys, D.

(2005) J Biological Chem 280: 30361-30366

Released	2005-07-05
Method	X-RAY DIFFRACTION 2.11 Å
Organisms	Homo sapiens
Macromolecule	Electron transfer flavoprotein alpha-subunit, mitochondrial precursor (protein) Electron transfer flavoprotein beta-subunit (protein)
Unique Ligands	AMP, FAD

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2ABA \| pdb_00002aba	Download File View File

Structure of reduced PETN reductase in complex with progesterone

Khan, H., Barna, T., Bruce, N.C., Munro, A.W., Leys, D., Scrutton, N.S.

(2005) FEBS J 272: 4660-4671

Released	2005-10-11
Method	X-RAY DIFFRACTION 1.05 Å
Organisms	Enterobacter cloacae
Macromolecule	pentaerythritol tetranitrate reductase (protein)
Unique Ligands	FMN, IPA, STR

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2ABB \| pdb_00002abb	Download File View File

Structure of PETN reductase Y186F in complex with cyanide

Khan, H., Barna, T., Bruce, N.C., Munro, A.W., Leys, D., Scrutton, N.S.

(2005) FEBS J 272: 4660-4671

Released	2005-10-11
Method	X-RAY DIFFRACTION 1 Å
Organisms	Enterobacter cloacae
Macromolecule	pentaerythritol tetranitrate reductase (protein)
Unique Ligands	FMN, IPA, SCN

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2AGL \| pdb_00002agl	Download File View File

Crystal structure of the phenylhydrazine adduct of aromatic amine dehydrogenase from Alcaligenes faecalis

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	PHZ

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2AGW \| pdb_00002agw	Download File View File

Crystal structure of tryptamine-reduced aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis in complex with tryptamine

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	TSS

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2AGX \| pdb_00002agx	Download File View File

Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. P212121 form

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	TSH

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2AGY \| pdb_00002agy	Download File View File

Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	TSH

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2AGZ \| pdb_00002agz	Download File View File

Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. F222 form

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	TSC, ZN

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2AH0 \| pdb_00002ah0	Download File View File

Crystal structure of the carbinolamine intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. Monoclinic form

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.45 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)
Unique Ligands	TSC, TSH

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2AH1 \| pdb_00002ah1	Download File View File

Crystal structure of aromatic amine dehydrogenase (AADH) from Alcaligenes faecalis

Masgrau, L., Roujeinikova, A., Johannissen, L.O., Hothi, P., Basran, J., Ranaghan, K.E., Mulholland, A.J., Sutcliffe, M.J., Scrutton, N.S., Leys, D.

(2006) Science 312: 237-241

Released	2006-04-25
Method	X-RAY DIFFRACTION 1.2 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic amine dehydrogenase (protein)

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2H3X \| pdb_00002h3x	Download File View File

Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes Faecalis (Form 3)

Sukumar, N., Chen, Z., Leys, D., Scrutton, N.S., Ferrati, D., Merli, A., Rossi, G.L., Bellamy, H.D., Chistoserdov, A., Davidson, V.L., Mathews, F.S.

(2006) Biochemistry 45: 13500-13510

Released	2006-11-21
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic Amine Dehydrogenase (protein) Azurin (protein)
Unique Ligands	CU

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2H47 \| pdb_00002h47	Download File View File

Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 1)

Sukumar, N., Chen, Z., Leys, D., Scrutton, N.S., Ferrati, D., Merli, A., Rossi, G.L., Bellamy, H.D., Chistoserdov, A., Davidson, V.L., Mathews, F.S.

(2006) Biochemistry 45: 13500-13510

Released	2006-11-21
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic Amine Dehydrogenase (protein) Azurin (protein)
Unique Ligands	CU

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2IAA \| pdb_00002iaa	Download File View File

Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 2)

Sukumar, N., Chen, Z., Leys, D., Scrutton, N.S., Ferrati, D., Merli, A., Rossi, G.L., Bellamy, H.D., Chistoserdov, A., Davidson, V.L., Mathews, F.S.

(2006) Biochemistry 45: 13500-13510

Released	2006-11-21
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Alcaligenes faecalis
Macromolecule	Aromatic Amine Dehydrogenase (protein) Azurin (protein)
Unique Ligands	CU

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1DJN | pdb_00001djn

1DJQ | pdb_00001djq

1O94 | pdb_00001o94

1O95 | pdb_00001o95

1O96 | pdb_00001o96

1O97 | pdb_00001o97

1PJ5 | pdb_00001pj5

1PJ6 | pdb_00001pj6

1PJ7 | pdb_00001pj7

1S24 | pdb_00001s24

1T9G | pdb_00001t9g

2A1T | pdb_00002a1t

2A1U | pdb_00002a1u

2ABA | pdb_00002aba

2ABB | pdb_00002abb

2AGL | pdb_00002agl

2AGW | pdb_00002agw

2AGX | pdb_00002agx

2AGY | pdb_00002agy

2AGZ | pdb_00002agz

2AH0 | pdb_00002ah0

2AH1 | pdb_00002ah1

2H3X | pdb_00002h3x

2H47 | pdb_00002h47

2IAA | pdb_00002iaa