RCSB PDB: Search

2NXY \| pdb_00002nxy	Download File View File

HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	HEZ, NAG, TRS

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2NXZ \| pdb_00002nxz	Download File View File

HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.04 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	EDO, HEZ, IPA, NAG
Unique branched monosaccharides	FRU, GLC

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2NY0 \| pdb_00002ny0	Download File View File

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	HEZ, NAG

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2NY1 \| pdb_00002ny1	Download File View File

HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	FRU, GLC

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2NY2 \| pdb_00002ny2	Download File View File

HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	EDO, HEZ, NAG
Unique branched monosaccharides	FRU, GLC

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2NY3 \| pdb_00002ny3	Download File View File

HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	FRU, GLC

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2NY4 \| pdb_00002ny4	Download File View File

HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	HEZ, NAG
Unique branched monosaccharides	FRU, GLC

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2NY5 \| pdb_00002ny5	Download File View File

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	FRU, GLC

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2NY6 \| pdb_00002ny6	Download File View File

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY 17B, HEAVY CHAIN (protein) ANTIBODY 17B, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein) T-cell surface glycoprotein CD4 (protein)
Unique Ligands	NAG
Unique branched monosaccharides	FRU, GLC

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2NY7 \| pdb_00002ny7	Download File View File

HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12

Zhou, T., Xu, L., Dey, B., Hessell, A.J., Van Ryk, D., Xiang, S.H., Yang, X., Zhang, M.Y., Zwick, M.B., Arthos, J., Burton, D.R., Dimitrov, D.S., Sodroski, J., Wyatt, R., Nabel, G.J., Kwong, P.D.

(2007) Nature 445: 732-737

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	ANTIBODY b12, HEAVY CHAIN (protein) ANTIBODY b12, LIGHT CHAIN (protein) ENVELOPE GLYCOPROTEIN GP120 (protein)
Unique Ligands	NAG

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3HI1 \| pdb_00003hi1	Download File View File

Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105

Kwon, Y.D., Chen, L., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z., Zhang, M.-Y., Arthos, J., Burton, D.R., Dimitrov, D., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.

(2009) Science 326: 1123-1127

Released	2009-11-17
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens Human immunodeficiency virus type 1 (isolate YU2)
Macromolecule	F105 Heavy Chain (protein) F105 Light Chain (protein) Glycoprotein 120 (protein)
Unique Ligands	NAG

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3IDX \| pdb_00003idx	Download File View File

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222

Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.

(2009) Science 326: 1123-1127

Released	2009-11-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Fab b13 heavy chain (protein) Fab b13 light chain (protein) HIV-1 HxBc2 gp120 core (protein)
Unique Ligands	EPE, GOL, NAG, SO4

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3IDY \| pdb_00003idy	Download File View File

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221

Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D.

(2009) Science 326: 1123-1127

Released	2009-11-17
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens Human immunodeficiency virus 1
Macromolecule	Fab b13 heavy chain (protein) Fab b13 light chain (protein) HIV-1 HxBc2 gp120 core (protein)
Unique Ligands	NAG, SO4

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4I3R \| pdb_00004i3r	Download File View File

Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221

Joyce, M.G., Biertumpfel, C., Nabel, G.J., Kwong, P.D.

(2013) J Virol 87: 2294-2306

Released	2013-01-09
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens Human immunodeficiency virus
Macromolecule	Heavy chain of VRC-PG04 Fab (protein) Light chain of VRC-PG04 Fab (protein) Outer domain of HIV-1 gp120 (KER2018 OD4.2.2) (protein)
Unique Ligands	NAG

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4I3S \| pdb_00004i3s	Download File View File

Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21

Joyce, M.G., Biertumpfel, C., Nabel, G.J., Kwong, P.D.

(2013) J Virol 87: 2294-2306

Released	2013-01-09
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Homo sapiens Human immunodeficiency virus
Macromolecule	Heavy chain of VRC-PG04 Fab (protein) Light chain of VRC-PG04 Fab (protein) Outer domain of HIV-1 gp120 (KER2018 OD4.2.2) (protein)
Unique Ligands	CA

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4Q6I \| pdb_00004q6i	Download File View File

Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4

Boyington, J.C., Nabel, G.J., Mascola, J.R.

(2014) Sci Transl Med 6: 243ra88-243ra88

Released	2014-07-23
Method	X-RAY DIFFRACTION 3.65 Å
Organisms	Homo sapiens Mus musculus
Macromolecule	Heavy chain of murine 2D5 Fab (protein) Light chain of murine 2D5 Fab (protein) T-cell surface glycoprotein CD4 (protein)

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5C0R \| pdb_00005c0r	Download File View File

Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179

Boyington, J.C., kwong, P.D., Nabel, G.J., Mascola, J.R.

(2015) Nat Med 21: 1065-1070

Released	2015-09-02
Method	X-RAY DIFFRACTION 3.188 Å
Organisms	HIV-1 M:B_HXB2R Influenza A virus (A/New Caledonia/20/1999(H1N1)) Mus musculus Tequatrovirus T4
Macromolecule	C179 Fab heavy chain (protein) C179 Fab light chain (protein) Hemagglutinin, Envelope glycoprotein, Fibritin fusion protein (protein)
Unique Ligands	NAG
Unique branched monosaccharides	NAG

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5C0S \| pdb_00005c0s	Download File View File

Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261

Boyington, J.C., Kwong, P.D., Nabel, G.J., Mascola, J.R.

(2015) Nat Med 21: 1065-1070

Released	2015-09-02
Method	X-RAY DIFFRACTION 4.3 Å
Organisms	HIV-1 M:B_HXB2R Homo sapiens Influenza A virus (A/New Caledonia/20/1999(H1N1)) Tequatrovirus T4
Macromolecule	CR6261 antibody heavy chain (protein) CR6261 antibody light chain (protein) Hemagglutinin, Envelope glycoprotein, Fibritin fusion protein (protein)

2NXY | pdb_00002nxy

HIV-1 gp120 Envelope Glycoprotein(S334A) Complexed with CD4 and Antibody 17b

2NXZ | pdb_00002nxz

HIV-1 gp120 Envelope Glycoprotein (T257S, S334A, S375W) Complexed with CD4 and Antibody 17b

2NY0 | pdb_00002ny0

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, T257S, V275C, S334A, S375W, A433M) Complexed with CD4 and Antibody 17b

2NY1 | pdb_00002ny1

HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b

2NY2 | pdb_00002ny2

HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b

2NY3 | pdb_00002ny3

HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E267C, S334A, S375W) Complexed with CD4 and Antibody 17b

2NY4 | pdb_00002ny4

HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b

2NY5 | pdb_00002ny5

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T257S, V275C, S334A, S375W, Q428C, A433M) Complexed with CD4 and Antibody 17b

2NY6 | pdb_00002ny6

HIV-1 gp120 Envelope Glycoprotein (M95W, W96C, I109C, T123C, T257S, V275C,S334A, S375W, Q428C, G431C) Complexed with CD4 and Antibody 17b

2NY7 | pdb_00002ny7

HIV-1 gp120 Envelope Glycoprotein Complexed with the Broadly Neutralizing CD4-Binding-Site Antibody b12

3HI1 | pdb_00003hi1

Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105

3IDX | pdb_00003idx

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222

3IDY | pdb_00003idy

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221

4I3R | pdb_00004i3r

Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221

4I3S | pdb_00004i3s

Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21

4Q6I | pdb_00004q6i

Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4

5C0R | pdb_00005c0r

Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179

5C0S | pdb_00005c0s

Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261

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Scientific Name of Source Organism

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Symmetry Type

SCOP Classification

2NXY | pdb_00002nxy

2NXZ | pdb_00002nxz

2NY0 | pdb_00002ny0

2NY1 | pdb_00002ny1

2NY2 | pdb_00002ny2

2NY3 | pdb_00002ny3

2NY4 | pdb_00002ny4

2NY5 | pdb_00002ny5

2NY6 | pdb_00002ny6

2NY7 | pdb_00002ny7

3HI1 | pdb_00003hi1

3IDX | pdb_00003idx

3IDY | pdb_00003idy

4I3R | pdb_00004i3r

4I3S | pdb_00004i3s

4Q6I | pdb_00004q6i

5C0R | pdb_00005c0r

5C0S | pdb_00005c0s