RCSB PDB: Search

2JGY \| pdb_00002jgy	Download File View File

The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)

Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-03-06
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	UMP SYNTHASE (protein)

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2JI4 \| pdb_00002ji4	Download File View File

Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41)

Moche, M., Lehtio, L., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kotenyova, T., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

To be published

Released	2007-03-06
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 2 (protein)
Unique Ligands	CL

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2JIS \| pdb_00002jis	Download File View File

Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.

Collins, R., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

To be published

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	CYSTEINE SULFINIC ACID DECARBOXYLASE (protein)
Unique Ligands	NO3, PLP

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2OXC \| pdb_00002oxc	Download File View File

Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP

Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

To be published

Released	2007-02-27
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Homo sapiens
Macromolecule	Probable ATP-dependent RNA helicase DDX20 (protein)
Unique Ligands	ADP

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2P6N \| pdb_00002p6n	Download File View File

Human DEAD-box RNA helicase DDX41, helicase domain

Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-04-03
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent RNA helicase DDX41 (protein)

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2PL3 \| pdb_00002pl3	Download File View File

Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-05-01
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	Probable ATP-dependent RNA helicase DDX10 (protein)
Unique Ligands	ADP, EOH, MG

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2PQF \| pdb_00002pqf	Download File View File

Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hogbom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2015) J Biological Chem 290: 7336-7344

Released	2007-05-15
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Poly [ADP-ribose] polymerase 12 (protein)
Unique Ligands	CIT, GAB

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2PSO \| pdb_00002pso	Download File View File

Human StarD13 (DLC2) lipid transfer and protein localization domain

Lehtio, L., Busam, R., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Ogg, D., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e19521-e19521

Released	2007-05-15
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	StAR-related lipid transfer protein 13 (protein)

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2Q9P \| pdb_00002q9p	Download File View File

Human diphosphoinositol polyphosphate phosphohydrolase 1, Mg-F complex

Thorsell, A.G., Busam, R., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Ogg, D., Sagemark, J., Sundstrom, M., Van den Berg, S., Weigelt, J., Welin, M., Persson, C., Hallberg, B.M., Structural Genomics Consortium (SGC)

(2009) Proteins 77: 242-246

Released	2007-09-11
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Diphosphoinositol polyphosphate phosphohydrolase 1 (protein)
Unique Ligands	CL, F, IHP, MG

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2QC8 \| pdb_00002qc8	Download File View File

Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hogbom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2008) J Mol Biology 375: 217-228

Released	2007-07-03
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Glutamine synthetase (protein)
Unique Ligands	ADP, CL, MN, P3S

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2QK4 \| pdb_00002qk4	Download File View File

Human glycinamide ribonucleotide synthetase

Lehtio, L., Welin, M., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

(2010) Nucleic Acids Res 38: 7308-7319

Released	2007-07-24
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Homo sapiens
Macromolecule	Trifunctional purine biosynthetic protein adenosine-3 (protein)
Unique Ligands	ATP, CL, GOL, SO4

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2QQ2 \| pdb_00002qq2	Download File View File

Crystal structure of C-terminal domain of Human acyl-CoA thioesterase 7

Busam, R., Lehtio, L., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

To be published

Released	2007-08-14
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	Cytosolic acyl coenzyme A thioester hydrolase (protein)

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2QZ4 \| pdb_00002qz4	Download File View File

Human paraplegin, AAA domain in complex with ADP

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, J., Sagemark, C., Sundstrom, M., Thorsell, A.G., Tresauges, L., Van Den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2009) PLoS One 4: e6975-e6975

Released	2007-09-11
Method	X-RAY DIFFRACTION 2.22 Å
Organisms	Homo sapiens
Macromolecule	Paraplegin (protein)
Unique Ligands	ADP

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2R55 \| pdb_00002r55	Download File View File

Human StAR-related lipid transfer protein 5

Lehtio, L., Busam, R.D., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e19521-e19521

Released	2007-09-18
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	StAR-related lipid transfer protein 5 (protein)

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2RF5 \| pdb_00002rf5	Download File View File

Crystal structure of human tankyrase 1- catalytic PARP domain

Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)

(2008) J Mol Biology 379: 136-145

Released	2007-10-09
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	Tankyrase-1 (protein)
Unique Ligands	GOL, ZN

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2UVL \| pdb_00002uvl	Download File View File

Human BIR3 domain of Baculoviral Inhibitor of Apoptosis Repeat- Containing 3 (BIRC3)

Moche, M., Lehtio, L., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kotenyova, T., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Upsten, M., Van Den Berg, S., Weigelt, J., Nordlund, P.

(2009) Acta Crystallogr Sect F Struct Biol Cryst Commun 65: 1091

Released	2007-03-27
Method	X-RAY DIFFRACTION 1.91 Å
Organisms	Homo sapiens
Macromolecule	BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3 (protein)
Unique Ligands	GOL, ZN

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2UZ9 \| pdb_00002uz9	Download File View File

Human guanine deaminase (guaD) in complex with zinc and its product Xanthine.

Moche, M., Welin, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-05-08
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	GUANINE DEAMINASE (protein)
Unique Ligands	XAN, ZN

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2V30 \| pdb_00002v30	Download File View File

Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.

Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-07-24
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (protein)
Unique Ligands	U5P

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2V40 \| pdb_00002v40	Download File View File

Human Adenylosuccinate synthetase isozyme 2 in complex with GDP

Welin, M., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-07-10
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 (protein)
Unique Ligands	GDP

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2V4M \| pdb_00002v4m	Download File View File

The isomerase domain of human glutamine-fructose-6-phosphate transaminase 1 (GFPT1) in complex with fructose 6-phosphate

Moche, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, S., Schueler, H., Thorsell, A.G., Tresaugues, L., Uppenberg, J., Van Den Berg, S., Welin, M., Wisniewska, M., Weigelt, J., Nordlund, P., Wikstrom, M.

To be published

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.29 Å
Organisms	Homo sapiens
Macromolecule	GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1 (protein)
Unique Ligands	CL, F6R

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2V4U \| pdb_00002v4u	Download File View File

Human CTP synthetase 2 - glutaminase domain in complex with 5-OXO-L- NORLEUCINE

Welin, M., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wisniewska, M., Weigelt, J., Wikstrom, M., Nordlund, P.

To be published

Released	2008-10-07
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	CTP SYNTHASE 2 (protein)

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2V9Y \| pdb_00002v9y	Download File View File

Human aminoimidazole ribonucleotide synthetase

Welin, M., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

(2010) Nucleic Acids Res 38: 7308

Released	2007-09-11
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (protein)
Unique Ligands	SO4