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6EVR \| pdb_00006evr	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 4-(4 acetyl-3-benzylpiperazine-1 carbonyl)benzene-1-sulfonamide inhibitor

Ferraroni, M., Supuran, C.T., Chiapponi, D., Chiaramonte, N.

(2018) Eur J Med Chem 151: 363-375

Released	2018-06-06
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	ACT, BZW, GOL, ZN

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6EX1 \| pdb_00006ex1	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 4-[(3S)-3 benzyl-4-(4-sulfamoylbenzoyl)piperazine -1-carbonyl]benzene-1-sulfonamide inhibitor

Ferraroni, M., Supuran, C.T., Chiapponi, D., Chiaramonte, N.

(2018) Eur J Med Chem 151: 363-375

Released	2018-10-10
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	ACT, GOL, N19, ZN

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6F3B \| pdb_00006f3b	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-[(4-methylphenyl)methyl]urea inhibitor

Ferraroni, M., Supuran, C.T., Chiapponi, D., Bozdag, M.

(2018) J Med Chem 61: 6328-6338

Released	2018-10-10
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	ACT, CJK, GOL, ZN

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6FAF \| pdb_00006faf	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 3-(2,5-dimethylphenyl)-1-(2-hydroxy-5-sulfamoylphenyl)urea inhibitor

Ferraroni, M., Supuran, C.T., Bozdag, M., Chiapponi, D.

(2018) J Med Chem 61: 6328-6338

Released	2018-10-10
Method	X-RAY DIFFRACTION 1.99 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	D3B, GOL, ZN

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6FAG \| pdb_00006fag	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-(2-methoxyphenyl)urea inhibitor

Ferraroni, M., Supuran, C.T., Bozdag, M., Chiapponi, D.

(2018) J Med Chem 61: 6328-6338

Released	2018-10-10
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	EON, GOL, ZN

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6I0J \| pdb_00006i0j	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor

Ferraroni, M., Supuran, C.T., Bozdag, M., Chiapponi, D.

(2019) Eur J Med Chem 182: 111600-111600

Released	2019-11-20
Method	X-RAY DIFFRACTION 1.35 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	ACT, GOL, GZE, ZN

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6I0L \| pdb_00006i0l	Download File View File

Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor

Ferraroni, M., Supuran, C.T., Bozdag, M., Chiapponi, D.

(2019) Eur J Med Chem 182: 111600-111600

Released	2019-11-20
Method	X-RAY DIFFRACTION 1.4 Å
Organisms	Homo sapiens
Macromolecule	Carbonic anhydrase 1 (protein)
Unique Ligands	ACT, GOL, GZH, ZN

6EVR | pdb_00006evr

Crystal structure of human carbonic anhydrase I in complex with the 4-(4 acetyl-3-benzylpiperazine-1 carbonyl)benzene-1-sulfonamide inhibitor

6EX1 | pdb_00006ex1

Crystal structure of human carbonic anhydrase I in complex with the 4-[(3S)-3 benzyl-4-(4-sulfamoylbenzoyl)piperazine -1-carbonyl]benzene-1-sulfonamide inhibitor

6F3B | pdb_00006f3b

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-[(4-methylphenyl)methyl]urea inhibitor

6FAF | pdb_00006faf

Crystal structure of human carbonic anhydrase I in complex with the 3-(2,5-dimethylphenyl)-1-(2-hydroxy-5-sulfamoylphenyl)urea inhibitor

6FAG | pdb_00006fag

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-(2-methoxyphenyl)urea inhibitor

6I0J | pdb_00006i0j

Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor

6I0L | pdb_00006i0l

Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor

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6EVR | pdb_00006evr

Crystal structure of human carbonic anhydrase I in complex with the 4-(4 acetyl-3-benzylpiperazine-1 carbonyl)benzene-1-sulfonamide inhibitor

6EX1 | pdb_00006ex1

Crystal structure of human carbonic anhydrase I in complex with the 4-[(3S)-3 benzyl-4-(4-sulfamoylbenzoyl)piperazine -1-carbonyl]benzene-1-sulfonamide inhibitor

6F3B | pdb_00006f3b

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-[(4-methylphenyl)methyl]urea inhibitor

6FAF | pdb_00006faf

Crystal structure of human carbonic anhydrase I in complex with the 3-(2,5-dimethylphenyl)-1-(2-hydroxy-5-sulfamoylphenyl)urea inhibitor

6FAG | pdb_00006fag

Crystal structure of human carbonic anhydrase I in complex with the 1-(2-hydroxy-5-sulfamoylphenyl)-3-(2-methoxyphenyl)urea inhibitor

6I0J | pdb_00006i0j

Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor

6I0L | pdb_00006i0l

Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4-sulfamoylphenyl)ethyl]urea inhibitor