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235,183 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Chen, H."

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Search Summary

This query matches 195 Structures.

Refinements

Structure Determination Methodology

experimental (195)

Scientific Name of Source Organism

	Homo sapiens (110)
	Mus musculus (8)
	Penaeus japonicus (6)
	Pseudomonas putida (6)
	Escherichia coli (5)
	Gallus gallus (5)
	synthetic construct (5)
	Alongshan virus (4)
	Bos taurus (3)
	Escherichia coli K-12 (3)

More...

Taxonomy

	Eukaryota (145)
	Bacteria (32)
	Riboviria (11)
	Duplodnaviria (8)
	other sequences (5)
	Eukaryota (eukaryotes) (2)
	Archaea (1)
	Varidnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (164)
	ELECTRON MICROSCOPY (23)
	SOLUTION NMR (8)

Polymer Entity Type

	Protein (187)
	DNA (15)
	RNA (12)

Refinement Resolution (Å)

	1.0 - 1.5 (4)
	1.5 - 2.0 (38)
	2.0 - 2.5 (63)
	2.5 - 3.0 (45)
	3.0 - 3.5 (25)
	3.5 - 4.0 (6)
	4.0 - 4.5 (4)
	> 4.5 (2)

Release Date

	1995 - 1999 (6)
	2000 - 2004 (13)
	2005 - 2009 (17)
	2010 - 2014 (29)
	2015 - 2019 (62)
	2020 - 2024 (67)
	2025 - 2029 (1)

Enzyme Classification Name

	Transferases (66)
	Oxidoreductases (23)
	Hydrolases (13)
	Isomerases (3)
	Ligases (1)
	Lyases (1)
	Translocases (1)

Membrane Protein Annotation

	OPM (15)
	PDBTM (17)
	mpstruc (14)
	MemProtMD (14)

Symmetry Type

	Asymmetric (108)
	Cyclic (67)
	Octahedral (15)
	Dihedral (3)

SCOP Classification

	All alpha proteins (43)
	Alpha and beta proteins (a+b) (57)
	Alpha and beta proteins (a/b) (9)
	Artifacts (12)
	All beta proteins (4)
	Small proteins (4)
	Coiled coil proteins (1)

AllSelected

1 to 25 of 195 Structures

Page 1 of 8

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193D \| pdb_0000193d	Download File View File

SOLUTION STRUCTURE OF A QUINOMYCIN BISINTERCALATOR-DNA COMPLEX

Chen, H., Patel, D.J.

(1995) J Mol Biology 246: 164

Released	1995-02-27
Method	SOLUTION NMR
Macromolecule	QUINOMYCIN (protein) DNA (5'-D(APCPAPCPGPTPGPT)-3') (nucleic acid)
Unique Ligands	HQU

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1CDW \| pdb_00001cdw	Download File View File

HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA

Nikolov, D.B., Chen, H., Halay, E.D., Hoffmann, A., Roeder, R.G., Burley, S.K.

(1996) Proc Natl Acad Sci U S A 93: 4862-4867

Released	1996-12-23
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TATA BINDING PROTEIN (TBP)) (protein) DNA (5'-D(CPAPGPCPCPTPTPTPTPAPTPAPGPCPAPG)-3') (nucleic acid) DNA (5'-D(CPTPGPCPTPAPTPAPAPAPAPGPGPCPTPG)-3') (nucleic acid)

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1DP7 \| pdb_00001dp7	Download File View File

COCRYSTAL STRUCTURE OF RFX-DBD IN COMPLEX WITH ITS COGNATE X-BOX BINDING SITE

Gajiwala, K.S., Chen, H., Cornille, F., Roques, B.P., Reith, W., Mach, B., Burley, S.K.

(2000) Nature 403: 916-921

Released	2000-03-06
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Homo sapiens
Macromolecule	MHC CLASS II TRANSCRIPTION FACTOR HRFX1 (protein) DNA (5'-D(CPGP(BRU)PTPAPCPCPAP(BRU)PGPGPTPAPAPCPG)-3') (nucleic acid)
Unique Ligands	EDO, PEG

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1DT4 \| pdb_00001dt4	Download File View File

CRYSTAL STRUCTURE OF NOVA-1 KH3 K-HOMOLOGY RNA-BINDING DOMAIN

Lewis, H.A., Chen, H., Edo, C., Buckanovich, R.J., Yang, Y.Y.L.

(1999) Structure 7: 191-203

Released	2000-02-11
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	NEURO-ONCOLOGICAL VENTRAL ANTIGEN 1 (protein)

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1DTJ \| pdb_00001dtj	Download File View File

CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN

Lewis, H.A., Chen, H., Edo, C., Buckanovich, R.J., Yang, Y.Y.L., Musunuru, K., Zhong, R., Darnell, R.B., Burley, S.K.

(1999) Structure 7: 191-203

Released	2000-02-18
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	RNA-BINDING NEUROONCOLOGICAL VENTRAL ANTIGEN 2 (protein)

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1EC6 \| pdb_00001ec6	Download File View File

CRYSTAL STRUCTURE OF NOVA-2 KH3 K-HOMOLOGY RNA-BINDING DOMAIN BOUND TO 20-MER RNA HAIRPIN

Lewis, H.A., Musunuru, K., Jensen, K.B., Edo, C., Chen, H.

(2000) Cell 100: 323-332

Released	2000-02-21
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	RNA-BINDING PROTEIN NOVA-2 (protein) 20-MER RNA HAIRPIN (nucleic acid)

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1EDU \| pdb_00001edu	Download File View File

CRYSTAL STRUCTURE OF THE ENTH DOMAIN OF RAT EPSIN 1

Hyman, J.H., Chen, H., Decamilli, P., Brunger, A.T.

(2000) J Cell Biol 149: 537-546

Released	2000-05-10
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Rattus norvegicus
Macromolecule	EH domain binding protein EPSIN (protein)
Unique Ligands	EDO

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1FJA \| pdb_00001fja	Download File View File

NMR STUDY OF DEOXYRIBONUCLEIC ACID COMPLEXED WITH ACTINOMYCIN D

Chen, H., Liu, X., Patel, D.J.

(1996) J Mol Biology 258: 457

Released	1996-06-10
Method	SOLUTION NMR
Organisms	Streptomyces antibioticus
Macromolecule	ACTINOMYCIN D (protein) DNA (5'-D(APAPGPCPGPCPTPT)-3') (nucleic acid)

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1FJB \| pdb_00001fjb	Download File View File

NMR Study of an 11-Mer DNA Duplex Containing 7,8-Dihydro-8-Oxoadenine (AOXO) Opposite Thymine

Chen, H., Johnson, F., Grollman, A.P., Patel, D.J.

(1996) Magn Reson Chem 34: 23

Released	1996-06-10
Method	SOLUTION NMR
Macromolecule	DNA (5'-D(CPGPTPAPCP(A38)PCPAPTPGPC)-3') (nucleic acid) DNA (5'-D(GPCPAPTPGPTPGPTPAPCPG)-3') (nucleic acid)

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1JFI \| pdb_00001jfi	Download File View File

Crystal Structure of the NC2-TBP-DNA Ternary Complex

Kamada, K., Shu, F., Chen, H., Malik, S., Stelzer, G., Roeder, R.G., Meisterernst, M., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2001) Cell 106: 71-81

Released	2001-07-11
Method	X-RAY DIFFRACTION 2.62 Å
Organisms	Homo sapiens
Macromolecule	TATA-BOX-BINDING PROTEIN (TBP) (protein) Transcription Regulator NC2 alpha chain (protein) Transcription Regulator NC2 beta chain (protein) 5'-D(GGPAPGPCPCPCPTPTPTPTPAPTPAPGPCPCPAPA)-3' (nucleic acid) 5'-D(TPTPGPGPCPTPAPTPAPAPAPAPGPGPGPCPTPCPC)-3' (nucleic acid)

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1KBH \| pdb_00001kbh	Download File View File

Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR

Demarest, S.J., Martinez-Yamout, M., Chung, J., Chen, H., Xu, W., Dyson, H.J., Evans, R.M., Wright, P.E.

(2002) Nature 415: 549-553

Released	2002-02-06
Method	SOLUTION NMR
Organisms	Homo sapiens Mus musculus
Macromolecule	CREB-BINDING PROTEIN (protein) nuclear receptor coactivator (protein)

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1KU9 \| pdb_00001ku9	Download File View File

X-ray Structure of a Methanococcus jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphylococcus aureus

Ray, S.S., Bonanno, J.B., Chen, H., de Lencastre, H., Wu, S., Tomasz, A., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)

(2002) Proteins 50: 170-173

Released	2002-12-25
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Methanocaldococcus jannaschii
Macromolecule	hypothetical protein MJ223 (protein)

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1MV5 \| pdb_00001mv5	Download File View File

Crystal structure of LmrA ATP-binding domain

Yuan, Y., Chen, H., Patel, D.

To be published

Released	2003-12-02
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Lactococcus lactis
Macromolecule	Multidrug resistance ABC transporter ATP-binding and permease protein (protein)
Unique Ligands	ADP, ATP, MG

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1OMY \| pdb_00001omy	Download File View File

Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch

Huang, Y., Huang, Q., Chen, H., Tang, Y., Miyake, H., Kusunoki, M.

(2003) Acta Crystallogr D Biol Crystallogr 59: 1635-1636

Released	2003-09-09
Method	X-RAY DIFFRACTION 2 Å
Organisms	Olivierus martensii
Macromolecule	Alpha-neurotoxin TX12 (protein)
Unique Ligands	ACY, CL

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1S9I \| pdb_00001s9i	Download File View File

X-ray structure of the human mitogen-activated protein kinase kinase 2 (MEK2)in a complex with ligand and MgATP

Ohren, J.F., Chen, H., Pavlovsky, A., Whitehead, C., Yan, C., McConnell, P., Delaney, A., Dudley, D.T., Sebolt-Leopold, J., Hasemann, C.A.

(2004) Nat Struct Mol Biol 11: 1192-1197

Released	2004-11-23
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 2 (protein)
Unique Ligands	5EA, ATP, MG

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1S9J \| pdb_00001s9j	Download File View File

X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a complex with ligand and MgATP

Ohren, J.F., Chen, H., Pavlovsky, A., Whitehead, C., Yan, C., McConnell, P., Delaney, A., Dudley, D.T., Sebolt-Leopold, J., Hasemann, C.A.

(2004) Nat Struct Mol Biol 11: 1192-1197

Released	2004-11-23
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Dual specificity mitogen-activated protein kinase kinase 1 (protein)
Unique Ligands	ATP, BBM, MG

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1T3J \| pdb_00001t3j	Download File View File

Mitofusin domain HR2 V686M/I708M mutant

Koshiba, T., Detmer, S.A., Kaiser, J.T., Chen, H., McCaffery, J.M., Chan, D.C.

(2004) Science 305: 858-862

Released	2004-08-17
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Mus musculus
Macromolecule	mitofusin 1 (protein)

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1VOL \| pdb_00001vol	Download File View File

TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX

Nikolov, D.B., Chen, H., Halay, E.D., Usheva, A.U., Hisatake, K., Lee, D.K., Roeder, R.G., Burley, S.K.

(1995) Nature 377: 119-128

Released	1996-11-08
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Arabidopsis thaliana Homo sapiens
Macromolecule	PROTEIN (TATA BINDING PROTEIN (TBP)) (protein) PROTEIN (TRANSCRIPTION FACTOR IIB (TFIIB)) (protein) DNA (5'-D(CPAPGPCPCPCPTPTPTPTPAPTPAPGPCPC)-3') (nucleic acid) DNA (5'-D(GPGPCPTPAPTPAPAPAPAPGPGPGPCPTPG)-3') (nucleic acid)