Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysine acetate
Lysine
Lysine acid
Lysina
Lysinum
Lysine monohydrate
L-Lysine
(S)-2,6-diaminohexanoic acid
L-Lysin
Lysine dihydrate
6-ammonio-L-norleucine
(S)-α,ε-diaminocaproic acid
L-2,6-Diaminocaproic acid
Lysine hydrochloride
(S)-lysine
L-lys
LYS
Brand Names
Smofkabiven Peripheral
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
8.5% Freamine III
Aminosyn RF Injection
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II
Olimel 3.3% E
Aminosyn II with Electrolytes in Dextrose with Calcium
Vamin N
Aminosyn 8.5% Injection With Electrolytes
Clinimix
Aminosyn
Nutrineal Pd4
Imubolic
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn II 7% With 50% Dextrose
Primene 10%
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Travasol Amino Acid Inj 8.5%
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Smofkabiven Electrolyte Free
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Olimel 7.6%
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
HepatAmine
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II 8.5% With 50% Dextrose
Aminosyn II and Dextrose
Plenamine
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Perikabiven
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn HF
Aminosyn II In Dextrose Injection
Aminosyn 3.5% M
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn II 8.5% Injection
Primene 10%-liq IV
Lysakare
Xyzmune
Clinimix E
Clinisol
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
RenAmin
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Olimel 5.7%
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 7.6% E
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Travasol E
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Vamin 18 Electrolyte-free
NephrAmine
Aminosyn-PF
Olimel 5.7% E
Premasol - sulfite-free (Amino Acid)
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Aminosyn 10% W Electrolytes
Aminosyn Sulfite Free
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn RF
Aminosyn-PF 10%
Aminosyn II in Dextrose
Primene
Novamine
Effervescent Potassium Chloride
Aminosyn 5%
Aminosyn 8.5%
Periolimel 2.5% E
Travasol Inj Without Electrolytes 8.5%
Travasol Inj Without Electrolytes 5.5%
Nephramine Liq IV
Travasol Amino Acid Inj 5.5%
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Travasol
Renamin (amino Acids) Injection
Smofkabiven
Synthamin
Olimel 4.4%
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
ProSol
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Hepatasol
Aminosyn-PF 7%
ProcalAmine
TrophAmine
Aminosyn II 7% With 10% Dextrose
Smofkabiven Extra Nitrogen Electrolyte Free
FreAmine HBC
Aminosyn II 5% Inj
FreAmine III
Aminosyn II 10% With Electrolytes
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Smofkabiven Extra Nitrogen
20% Prosol
Aminosyn II with Electrolytes
Essepna
Olimel 4.4% E
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn II 7% Injection
Aminosyn 7%
Kabiven
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
