DrugBank ID DB00878 Name Chlorhexidine Groups approved withdrawn vet_approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Chlorhexidinum Chlorhexidin Chlorhexidine gluconate Cloresidina
Chlorhexidine Chlorhexidine acetate Clorhexidina Chlorhexidine hydrochloride 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) more Brand Names Steri-stat Tincture (tinted) Antis Prep Gel Ic-gel Pre and Post Sx Pouch Calgon Vestal 2% Chg Antimicrob.skin Cleans. Soluprep AQ Swab
PS1 Aciurgy Pack Scrub, Scrub-Stat Baxedin Pre-OP Ultrastat Chlorhexidine 4% Antiseptic Hand Wash Dexidin 2 Detergent Cardinal Health Antiseptic Skin Cleanser Aplicare Antiseptic Chlorhexidine Gluconate Avagard Chg Gum Paroex Bactoshield CHG Chlorhexidine Gluconate Solution 3M SoluPrep S Purell Antimicrobial Foam Handwash 2% Chg Eyewash Station Additive Concentrate Hibiclens Loris I.V. Pro - Sponge Stat Touch 2 Antimicrobial Skin Cleanser Soft Care 2% Chg Antimicrobial Skin Cleanser Foaming Chlorhexidine Gluconate Septi-san Rougier Vap-chlorhexidine Gluconate 2% W/V Sunberry Rinse free Hand Sanitizer Dermsafe Pc Soft Care Antiseptic Hand Soap Loris 2% Chg Solution Chlorhexidine 2% Antiseptic Hand Wash Purell CS Foam Handwash 2% CHG Euro-chlorhexidine Jisberry Hand Sanitizer Ostar Antimicrobial Hand Soap 2% - Liquid Anti Mucedine Feminine Wash Hands-free skin sanitizer Stanhexidine 4% With Isopropyl Alcohol 4% Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Cardinal Health Prevantics Maxi Swabstick Serdaen Germi-stat Prep Gel Chlorhexidine Gluconate 0.12% Oral Rinse Dyna-hex 2 Antiseptic Foam Handwash Stanhexidine 2% With Isopropyl Alcohol 4% Rougier Clean Derm Antiseptic Skin Cleanser Stanhexidine Red Tincture 0.5% DermacinRx Clorhexacin Major Oral Rinse Hygienipak 4% Chg Foaming Skin Cleanser KIMVENT ORAL CARE Q4 Kit WITH CHG Perichlor Soluprep AQ Applicator Cida-stat Liq Instillagel Soluprep Antiseptic Skin Cleanser Preoperative Kit Bactigras DEQGEL Advanced Hand Sanitizer (Fruli) Quick-Dry Disposable Hand Sanitizer Savlon Hospital Concentrate Sterigel Plus Chlorhexidine Gluconante Motherwort Herb Feminine Antibacterial Gels Germi Stat Gel 2% Periogard Antiseptic Body Cleanser Chlorhexseptic-liq 0.5mg/ml Soluprep AQ Sponge Baxedin Hibiclens Antiseptic/antimicrobial Skin Cleanser Scrub Care Exidine -4 CHG Soluprep Qd Wipe QCare Rx Petite Oral Cleansing and Suctioning System Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Foam Care Chg Surgical Hand Scrub Antiseptic Solution Chlorhexidine and Isopropyl Alcohol Prep Pads Hygienium Loris - I.V. Freeman Packing Alcohol Wipe Prevora Stage 1 Soluprep Qd Solution Akilspray Hand Sanitizer Peridex Bactoshield Chg 4% Loris I.V. Pro - Prefilled Applicator With Solution Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Chlorhexidine Gluconate Solution 0.75% Antiseptic Hand Sanitizer Gel Biokaab Antibacterial Protective Hand Spectro Tar Antiseptic Shampoo Liquivida Hydration E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Chlorhexidine Liq 0.05% Chloraprep Swabsticks Chlorhexidine gluconate Dexidin Liq 4% Alcohol Antibacterial Wipes Spray On Plastic Bandage Non-aerosol Kimvent Oral Care Q2 Kit with CHG Liszt Hand sanitizer without washing Hibitane Skin Cleanser Chlorhexidine Solution E-Z Scrub 107 Microban Medical Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Laura Line Chlorhexidine Antiseptic Soap Scrub Care Exidine-2 CHG SAITENM Health Wet wipes Chlorhexidine Surgical Continuum System 3M SoluPrep PhysiciansCare Eyewash Station Additive Concentrate Chinese Herb Essence Bacteriostatic Feminine Wash Bacti-stat Chg Dermawerx Surgical Plus Pak Solunet C Brosse 4% Peridex Oral Rinse Soluprep Swab PerioChip Hexirex Antiseptic Skin Cleanser Germi-stat 0.5% Antiseptic Prep Gel Purell Antimicrobial Foam Scrub Stat 4 Foam Liq Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Hand wipes Dexidin 0.5 Solution Steri-stat Liq 4.0% Salvesept Crm Ezy-TM Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Scrub-stat IV 4% Oral Cleansing and Suctioning System, q4 Spectro Gram 2 Skin Cleanser NUPRO Chlorhexidine Gluconate Sanital Antibacterial Hand Soap Baxedin 2% - 70% Periogard Alcohol Free Quick-drying rinse-free hand skin disinfectant Prevantics Swabstick Scrub B-good Hand and Skin Disinfecting Agent Rouhex G 20% Yu Ding Antibacterial Sprays 10mL Hibitane Skin Cleanser Liq 4% Chlorhexidine Gluconate Oral Rinse LARA MED Antibacterial Wet Wipes QCare Rx Oral Cleansing and Suctioning System, Q2 Soluprep AQ Wipe Hygienipak 4% Chg Skin Cleanser Foam Safe NuSurgePak Surgical Prep/CarePak Smart San CHG Perioselect Antimicrobial Sol 0.12% (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Dyna-hex 4 Plant Herb Based Bacteriostatic Feminine Wash Bactoshield Chg 2% JIANLIANG Antibacterial Sprays 10mL Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes PS2 Aciurgy Pack Dr. Luke Wart Remover Calgon Vestal 4% Chg Antimicrob.skin Cleans. Dyna-Hex 2 X-pur Chlorhexidine Savlodil Soluprep AQ ReadyPrep CHG Laura Line Antibacterial Cream Soap 2% Steri-stat Liq 2.0% Quick-Drying Hand Sanitizer Rugby Antiseptic Skin Cleanser BD E-Z Scrub Oris Chx Chlorhexidine Alcohol Free Chloraprep Liq 0.5% Dr. Luke Molluscum Wart Remover Oro Clear Anti-bac Hand ICEKING Skin Expert Refreshing Body Roller Dyna-Hex 4 Bactoshield CHG Chlorhexidine Gluconate Dr. Dean Protective Hand WhyteDerm SurgiPak Foaming Hand Antiseptic With Chg 2% Endure 400 Scrub-Stat 4 Disinfectant Wet Tissues Chlora-cleanze Endure 420 Cida-Stat Purmist First Aid Antiseptic Skin Cleanser Rouhex G 4% Hand Wipes Disinfectant Fabric Wash Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Gelato Chlorohexidine Soluprep Chlorhexidine Gluconate Applicator Dermawerx Surgical PrePak E-Z Scrub 747 4% Oral Cleansing and Suctioning System, q2 Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Antiseptic Skin Cleanser Exidine-2 CHG Hygenipak 2% Chg Skin Cleanser Tai Yu Ling Antibacterial Sprays 10mL Hexicinide Provon Antimicrobial Foam Handwash Scrub-Stat Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Hand Sanitizer Chlorhexidine and Isopropyl Alcohol Swabsticks Noble 75% Alcohol Wipes Prevantics Swab Sky Oral Rinse Dr. Zheng s acteriostatic gel Pro-dentx Chlorhexidene Oral Rinse DASH Chlorhexidine Gluconate 0.12% Oral Rinse Henry Schein Antimicrobial Skin Cleanser Pre-Scrub II Surgical Hand Scrub Aplicare Chlorhexidine Gluconate 2% Solution Steri-stat Liq 20% CliniClean Loris 2% Chg Wipe/serviette ChloraPrep One-Step Hibiclens for Georgia Pacific Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Periogard (Chlorhexidine Gluconate) Soluprep Ld Sponge Smart Sense Antiseptic Skin Cleanser Loris I.V. Pro - Swabstick Chloraprep DermacinRx Surgical PharmaPak Hygenipak 2% Chg Foaming Skin Cleanser Chlorhexidine Gluconate Pre-moistened Towelette Surgical and healthcare personnel hand antiseptic with moisturizers Chlorhexidine-cetrimide Soltn Conc HandSoap Disinfectant Spray(Speedy effect type) Hexifoam-skin Disinfectant Aer 1% Hibitane Skin Cleanser 2% Foaming Hand Wash CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse SANIDEP Advanced Sanitizer with Organic Extracts Scrub, Scrub-Stat, Foam Safe, Micro-Guard Chlorhexidine Gluconate Solution 0.05% QCare Rx Oral Cleansing and Suctioning System, Q4 Sterixin 0.05% Seaqua X Bactoshield CHG Zedoary Oils Feminine Antibacterial Gels Spray On Plastic Bandage Aerosol Stanhexidine 20% Flamazine C Germi Stat Gel 4% Q2 Oral Care Kit with CHG Hibistat Germicidal Hand Rinse Dyna-Hex 75 Bioprep 3M Avagard Avidene Surgical Scrub Dexidin 2 Solution Chlorhexidine Gluconate 0.12% Oral Rinse, USP Perichlor Without Alcohol Antiseptic Lotion Soap 2% Soluprep Wipe Chlorhexidine Gluconate, 0.12% Oral Rinse Chlorhexidine 0.5% Liq Rouhex G Liq 2% 3m Soluprep Sponge Oronine H Ointment 1% Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Hand Sanitizer Biokaab Steri-clean QCare Rx Oral Cleansing and Suctioning System Selpak Antibacterial Wet Wipes Cida-stat Foam Scrub Care Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Wart Remover Ointment. Bactoshield KleerSight Skin antisepsis, oral cleansing, nasal antisepsis Dexidin 20 Wart Removal Pen Provon Antiseptic Lotion Soap With 2% Chg BD E-Z Scrub 107 Alcohol Disinfectant Wipes Antiseptic Cleanser Solution Soluprep Antiseptic Skin Cleanser Sponge Soluprep Qd Swab Hibitane Skin Cleanser 4% Betasept DermacinRx Surgical ComboPak Wart removal Hibidil Antiseptic First Aid Spray Peridex Oral Rinse 0.12% Akilgeld Hand Sanitizer Paroex Antimicrobial Skin Cleanser Foster and Thrive Hibistat Antiseptic Cleansing Wipes CLIP Liquid Sanitizer Oro-clense Baxedin Liq 20% Antimicrobial Foam Handwash Burn O Sol Spray Soluprep Applicator Chlorhexidine Gluconate Solution USP 20% Prevantics swabstick Germi-stat 2% Foaming Liquid Bioprep Liq more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
