VAL

VALINE



Chemical Component Summary

NameVALINE
Identifiers(2S)-2-amino-3-methyl-butanoic acid
FormulaC5 H11 N O2
Molecular Weight117.146
TypeL-PEPTIDE LINKING
Isomeric SMILESCC(C)[C@@H](C(=O)O)N
InChIInChI=1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
InChIKeyKZSNJWFQEVHDMF-BYPYZUCNSA-N

Chemical Details

Formal Charge0
Atom Count19
Chiral Atom Count1
Bond Count18
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB00161 
NameValine
Groups
  • nutraceutical
  • approved
DescriptionValine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Synonyms
  • 2-Amino-3-methylbutyric acid
  • L-valin
  • L-valine
  • Valine
  • L-(+)-alpha-Aminoisovaleric acid
Brand Names
  • 2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
  • Aminosyn II with Electrolytes
  • 2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
  • 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
  • 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
IndicationPromotes mental vigor, muscle coordination, and calm emotions. May also be of use in a minority of patients with hepatic encephalopathy and in some with phenylketonuria.
Categories
  • Amino Acids
  • Amino Acids, Branched-Chain
  • Amino Acids, Essential
  • Amino Acids, Peptides, and Proteins
  • Dietary Supplements
CAS number72-18-4

Drug Targets

NameTarget SequencePharmacological ActionActions
Propionyl-CoA carboxylase beta chain, mitochondrialMAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGG...unknown
Branched-chain-amino-acid aminotransferase, cytosolicMKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFG...unknown
Valine--tRNA ligaseMSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRT...unknown
Valine--tRNA ligaseMSTLYVSPHPDAFPSLRALIAARYGEAGEGPGWGGAHPRICLQPPPTSRT...unknownsubstrate
Propionyl-CoA carboxylase beta chain, mitochondrialMAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGG...unknownsubstrate
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 88733505, 6287, 6971018
ChEMBL CHEMBL43068
ChEBI CHEBI:57762, CHEBI:16414
CCDC/CSD FIYWIW, VALHCL12, ROKBOI02, LUDHAT, HOSMAE, WIHQUA, VALEHC11, OXEMEL, AHEJEC01, AHEJEC03, FACXUD, SONCED, VALHCL11, BANPOW, AHEJEC, BERPET, HOTXIY, VALIDL05, AHEJEC02, ABEHOF, NUZMIG, OPEFUL, UHEPIG, TUZJIJ, QURSUR, FITMEA, EWOZIZ, RUXWIQ, VALNIT01, HAGYEU, PAHCIL, GUQJUZ, DLVALC, ROKBOI, VALEHC10, OCOLID, MAZBOI, MAZBIC
COD 2203771, 2202036