UQ1

UBIQUINONE-1

Created:	1999-07-08
Last modified:	2024-09-27

Find Related PDB Entry
53 entries where UQ1 is found as a standalone ligand1 entries where UQ1 is covalently linked to polymer or other heterogen groups

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	36
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	0

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	UBIQUINONE-1
Systematic Name (OpenEye OEToolkits)	2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione
Formula	C₁₄ H₁₈ O₄
Molecular Weight	250.29
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1C(=C(C(=O)C(OC)=C1OC)C)C\C=C(/C)C
SMILES	CACTVS	3.341	COC1=C(OC)C(=O)C(=C(C)C1=O)CC=C(C)C
SMILES	OpenEye OEToolkits	1.5.0	CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)C
Canonical SMILES	CACTVS	3.341	COC1=C(OC)C(=O)C(=C(C)C1=O)CC=C(C)C
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)C
InChI	InChI	1.03	InChI=1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3
InChIKey	InChI	1.03	SOECUQMRSRVZQQ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB08689
Name	Ubiquinone Q1
Groups	experimental
Synonyms	Ubiquinone-1 Coenzyme Q5 Ubiquinone 5 Ubiquinone Q1 CoQ1 Coenzyme Q1
Categories	Benzoquinones Coenzymes Enzymes and Coenzymes Quinones
CAS number	727-81-1

Drug Targets

Name	Target Sequence	Pharmacological Action
Photosynthetic reaction center cytochrome c subunit	MKQLIVNSVATVALASLVAGCFEPPPATTTQTGFRGLSMGEVLHPATVKA...	unknown
Reaction center protein H chain	MYHGALAQHLDIAQLVWYAQWLVIWTVVLLYLRREDRREGYPLVEPLGLV...	unknown
Reaction center protein L chain	MALLSFERKYRVRGGTLIGGDLFDFWVGPYFVGFFGVSAIFFIFLGVSLI...	unknown
Reaction center protein M chain	MADYQTIYTQIQARGPHITVSGEWGDNDRVGKPFYSYWLGKIGDAQIGPI...	unknown
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDS...	unknown
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial	MAAVVALSLRRRLPATTLGGACLQASRGAQTAAATAPRIKKFAIYRWDPD...	unknown
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial	MAVLWRLSAVCGALGGRALLLRTPVVRPAHISAFLQDRPIPEWCGVQHIH...	unknown
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	MAALLLRHVGRHCLRAHFSPQLCIRNAVPLGTTAKEEMERFWNKNIGSNR...	unknown
Thiol:disulfide interchange protein DsbA	MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCP...	unknown
Disulfide bond formation protein B	MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCA...	unknown
NrfC protein	MPRYAMAIDLSLCVGCAACAVACKMENEVPPGVFNLWIREREVGEYPNLV...	unknown
Thiosulfate reductase	MQRREFLKLSALGVGAMALRGSGPAKALKAPWYAQEVKSVYQICEGCFWR...	unknown
Hypothetical membrane spanning protein	MAEFYGLPNAQEFWHWTNALHFVLVGLAGGVALLAALLHLKGDAEARRYT...	unknown
View More

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682