TRO

2-HYDROXY-TRYPTOPHAN

Created: 1999-07-08
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count28
Chiral Atom Count1
Bond Count29
Aromatic Bond Count10
2D diagram of TRO
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Chemical Component Summary

Name2-HYDROXY-TRYPTOPHAN
Systematic Name (OpenEye OEToolkits)(2S)-2-amino-3-(2-hydroxy-1H-indol-3-yl)propanoic acid
FormulaC11 H12 N2 O3
Molecular Weight220.225
TypeL-PEPTIDE LINKING

Chemical Descriptors

TypeProgram Version Descriptor
SMILESACDLabs10.04O=C(O)C(N)Cc2c1ccccc1nc2O
SMILESCACTVS3.341N[CH](Cc1c(O)[nH]c2ccccc12)C(O)=O
SMILESOpenEye OEToolkits1.5.0c1ccc2c(c1)c(c([nH]2)O)CC(C(=O)O)N
Canonical SMILESCACTVS3.341 N[C@@H](Cc1c(O)[nH]c2ccccc12)C(O)=O
Canonical SMILESOpenEye OEToolkits1.5.0 c1ccc2c(c1)c(c([nH]2)O)C[C@@H](C(=O)O)N
InChIInChI1.03 InChI=1S/C11H12N2O3/c12-8(11(15)16)5-7-6-3-1-2-4-9(6)13-10(7)14/h1-4,8,13-14H,5,12H2,(H,15,16)/t8-/m0/s1
InChIKeyInChI1.03 VAUYGGXCASQWHK-QMMMGPOBSA-N

Drug Info: DrugBank

DrugBank IDDB03679 
Name2-Hydroxy-Tryptophan
Groups experimental
Synonyms2-Hydroxy-Tryptophan

Drug Targets

NameTarget SequencePharmacological ActionActions
Quinohemoprotein ethanol dehydrogenase type-1MERLIDNSHGWPGRMVWLLAACLGSAAAFAQTGPAAQAAAAVQRVDGDFI...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 17754204
ChEBI CHEBI:74690