SAN

SULFANILAMIDE

Created:	1999-07-08
Last modified:	2011-06-04

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6 entries where SAN is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	19
Chiral Atom Count	0
Bond Count	19
Aromatic Bond Count	6

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Chemical Component Summary
Name	SULFANILAMIDE
Systematic Name (OpenEye OEToolkits)	4-aminobenzenesulfonamide
Formula	C₆ H₈ N₂ O₂ S
Molecular Weight	172.205
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=S(=O)(c1ccc(N)cc1)N
SMILES	CACTVS	3.341	Nc1ccc(cc1)[S](N)(=O)=O
SMILES	OpenEye OEToolkits	1.5.0	c1cc(ccc1N)S(=O)(=O)N
Canonical SMILES	CACTVS	3.341	Nc1ccc(cc1)[S](N)(=O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1cc(ccc1N)S(=O)(=O)N
InChI	InChI	1.03	InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKey	InChI	1.03	FDDDEECHVMSUSB-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00259
Name	Sulfanilamide
Groups	approved
Description	Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Synonyms	Streptocide 4-azanylbenzenesulfonamide p-aminobenzenesulfonamide Prontosil album SA p-aminobenzenesulfamide Sulfanilamide Sulfamine para-aminobenzenesulfonamide 4-aminobenzene sulfonic acid amide Sulphanilamide Sulfanilamida Sulfanilamidum
Brand Names	Avc Cream - 15% AVC Vaginal Avc
Indication	For the treatment of vulvovaginitis caused by <i>Candida albicans</i>.
Categories	Amides Amines Aniline Compounds Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Benzene Derivatives Benzenesulfonamides Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 Enzyme Inhibitors Dermatologicals Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Methemoglobinemia Associated Agents Short-Acting Antibacterial Sulfonamides Sulfanilamides Sulfonamide Antibacterial Sulfonamides Sulfonamides and trimethoprim Sulfones Sulfur Compounds
ATC-Code	G01AE10 J01EB06 D06BA05
CAS number	63-74-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Dihydropteroate synthase	MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINA...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL21
PubChem	5333, 129828936
ChEMBL	CHEMBL21
ChEBI	CHEBI:45373
CCDC/CSD	SULAMD07, HUWHEO, SULAMD08, SULAMD10, BEYZEM, YORREC, SULAMD12, VOHKAG, SULAMD11, XIFNAC01, SANAPY, JEMVIG, SULAMD03, NUMHIO, STHSAM01, SULAMD06, ZILNEP, VIJYES, SULAMD04, UVATOD, SULAMD14, SULAMD13, QAJGIV
COD	4516494, 1519191, 1519208, 1519207, 1519216, 1519228, 2016567, 1542815